Patents by Inventor Keisuke Tazuru

Keisuke Tazuru has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION DRUG
    Publication number: 20250127813
    Abstract: The present invention discloses administering pharmaceutical compositions in combination, one of which is a pharmaceutical composition containing a tolinapant drug, and the other of which is a pharmaceutical composition containing an immune cell modified to express a chimeric antigen receptor or a recombinant T-cell receptor.
    Type: Application
    Filed: August 19, 2022
    Publication date: April 24, 2025
    Applicant: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Masayuki SONE, Hironori MATSUYAMA, Keisuke TAZURU, Yosuke KOGUE, Hiroki AKAMINE, Toshiki SUDO
  • Glycosylated polypeptide and pharmaceutical composition containing same
    Patent number: 10358470
    Abstract: The object of the present invention is to provide a glycosylated polypeptide having uniform sugar chain structure which has interferon ? activity. It was found that a glycosylated polypeptide having uniform sugar chain structure as well as having interferon ? activity can be prepared by a method comprising a step of synthesizing a glycosylated peptide fragment and at least two peptide fragments and a step of linking the glycosylated peptide fragment and the at least two peptide fragments.
    Type: Grant
    Filed: September 28, 2012
    Date of Patent: July 23, 2019
    Assignee: GLYTECH, INC.
    Inventors: Izumi Sakamoto, Kazuhiro Fukae, Katsunari Tezuka, Keisuke Tazuru, Masatoshi Maeda, Yasuhiro Kajihara, Takashi Tsuji
  • Sugar chain-polypeptide complex
    Patent number: 9981059
    Abstract: The object of the present invention is to provide a sugar chain-polypeptide complex that may form a transparent and homogeneous hydrogel in a broad pH. The present invention provides a sugar chain-polypeptide complex, characterized in that said polypeptide is a polypeptide comprising an amino acid sequence consisting of 8-34 amino acid residues in which polar and nonpolar amino acid residues are alternately arranged, and one or more sugar chains are bound to said polypeptide.
    Type: Grant
    Filed: March 21, 2014
    Date of Patent: May 29, 2018
    Assignee: GLYTECH, INC.
    Inventors: Hayato Saijo, Hirofumi Ochiai, Keisuke Tazuru, Taiji Shimoda
  • Glycosylated polypeptide and drug composition containing said polypeptide
    Patent number: 9937264
    Abstract: [Problem] To provide a glycosylated polypeptide having an affinity to somatostatin receptors, and, compared to somatostatins, having improved in-blood stability. [Solution] The glycosylated polypeptide is characterized by at least one amino acid in a somatostatin or an analog thereof being replaced with a glycosylated amino acid.
    Type: Grant
    Filed: July 8, 2016
    Date of Patent: April 10, 2018
    Assignee: GLYTECH, INC.
    Inventors: Hirofumi Ochiai, Taiji Shimoda, Kazuhiro Fukae, Masatoshi Maeda, Kazuyuki Ishii, Kenta Yoshida, Katsunari Tezuka, Keisuke Tazuru
  • Glycosylated polypeptide and drug composition containing said polypeptide
    Patent number: 9802996
    Abstract: [Problem] To provide a glycosylated polypeptide having affinity to somatostatin receptors and, compared to somatostatins, having improved in-blood stability. [Solution] The glycosylated polypeptide is characterized by at least two amino acids in a somatostatin or an analog thereof being replaced by glycosylated amino acids.
    Type: Grant
    Filed: July 19, 2016
    Date of Patent: October 31, 2017
    Assignee: Glytech, Inc.
    Inventors: Hirofumi Ochiai, Taiji Shimoda, Kazuhiro Fukae, Masatoshi Maeda, Keisuke Tazuru, Kenta Yoshida
  • Glycosylated Polypeptide and Drug Composition Containing said Polypeptide
    Publication number: 20170157260
    Abstract: [Problem] To provide a glycosylated polypeptide having an affinity to somatostatin receptors, and, compared to somatostatins, having improved in-blood stability. [Solution] The glycosylated polypeptide is characterized by at least one amino acid in a somatostatin or an analogue thereof being replaced with a glycosylated amino acid.
    Type: Application
    Filed: July 8, 2016
    Publication date: June 8, 2017
    Inventors: Hirofumi Ochiai, Taiji Shimoda, Kazuhiro Fukae, Masatoshi Maeda, Kazuyuki Ishii, Kenta Yoshida, Katsunari Tezuka, Keisuke Tazuru
  • Glycosylated Polypeptide and Drug Composition Containing said Polypeptide
    Publication number: 20160368961
    Abstract: [Problem] To provide a glycosylated polypeptide having affinity to somatostatin receptors and, compared to somatostatins, having improved in-blood stability. [Solution] The glycosylated polypeptide is characterized by at least two amino acids in a somatostatin or an analogue thereof being replaced by glycosylated amino acids.
    Type: Application
    Filed: July 19, 2016
    Publication date: December 22, 2016
    Inventors: Hirofumi Ochiai, Taiji Shimoda, Kazuhiro Fukae, Masatoshi Maeda, Keisuke Tazuru, Kenta Yoshida
  • Glycosylated polypeptide and drug composition containing said polypeptide
    Patent number: 9441024
    Abstract: [Problem] To provide a glycosylated polypeptide having affinity to somatostatin receptors and, compared to somatostatins, having improved in-blood stability. [Solution] The glycosylated polypeptide is characterized by at least two amino acids in a somatostatin or an analogue thereof being replaced by glycosylated amino acids.
    Type: Grant
    Filed: September 3, 2012
    Date of Patent: September 13, 2016
    Assignee: Glytech, Inc.
    Inventors: Hirofumi Ochiai, Taiji Shimoda, Kazuhiro Fukae, Masatoshi Maeda, Keisuke Tazuru, Kenta Yoshida
  • Glycosylated polypeptide and drug composition containing said polypeptide
    Patent number: 9422357
    Abstract: [Problem] To provide a glycosylated polypeptide having an affinity to somatostatin receptors, and, compared to somatostatins, having improved in-blood stability. [Solution] The glycosylated polypeptide is characterized by at least one amino acid in a somatostatin or an analog thereof being replaced with a glycosylated amino acid.
    Type: Grant
    Filed: September 3, 2012
    Date of Patent: August 23, 2016
    Assignee: Glytech, Inc.
    Inventors: Hirofumi Ochiai, Taiji Shimoda, Kazuhiro Fukae, Masatoshi Maeda, Kazuyuki Ishii, Kenta Yoshida, Katsunari Tezuka, Keisuke Tazuru
  • SUGAR CHAIN-POLYPEPTIDE COMPLEX
    Publication number: 20160129150
    Abstract: The object of the present invention is to provide a sugar chain-polypeptide complex that may form a transparent and homogeneous hydrogel in a broad pH. The present invention provides a sugar chain-polypeptide complex, characterized in that said polypeptide is a polypeptide comprising an amino acid sequence consisting of 8-34 amino acid residues in which polar and nonpolar amino acid residues are alternately arranged, and one or more sugar chains are bound to said polypeptide.
    Type: Application
    Filed: March 21, 2014
    Publication date: May 12, 2016
    Inventors: Hayato Saijo, Hirofumi Ochiai, Keisuke Tazuru, Taiji Shimoda
  • GLYCOSYLATED POLYPEPTIDE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME
    Publication number: 20140369964
    Abstract: The object of the present invention is to provide a glycosylated polypeptide having uniform sugar chain structure which has interferon ? activity. It was found that a glycosylated polypeptide having uniform sugar chain structure as well as having interferon ? activity can be prepared by a method comprising a step of synthesizing a glycosylated peptide fragment and at least two peptide fragments and a step of linking the glycosylated peptide fragment and the at least two peptide fragments.
    Type: Application
    Filed: September 28, 2012
    Publication date: December 18, 2014
    Inventors: Izumi Sakamoto, Kazuhiro Fukae, Katsunari Tezuka, Keisuke Tazuru, Masatoshi Maeda, Yasuhiro Kajihara, Takashi Tsuji
  • Glycosylated Polypeptide and Drug Composition Containing Said Polypeptide
    Publication number: 20140336116
    Abstract: [Problem] To provide a glycosylated polypeptide having an affinity to somatostatin receptors, and, compared to somatostatins, having improved in-blood stability. [Solution] The glycosylated polypeptide is characterized by at least one amino acid in a somatostatin or an analog thereof being replaced with a glycosylated amino acid.
    Type: Application
    Filed: September 3, 2012
    Publication date: November 13, 2014
    Applicant: Glytech, Inc.
    Inventors: Hirofumi Ochiai, Taiji Shimoda, Kazuhiro Fukae, Masatoshi Maeda, Kazuyuki Ishii, Kenta Yoshida, Katsunari Tezuka, Keisuke Tazuru
  • Glycosylated Polypeptide and Drug Composition Containing Said Polypeptide
    Publication number: 20140315800
    Abstract: [Problem] To provide a glycosylated polypeptide having affinity to somatostatin receptors and, compared to somatostatins, having improved in-blood stability. [Solution] The glycosylated polypeptide is characterized by at least two amino acids in a somatostatin or an analogue thereof being replaced by glycosylated amino acids.
    Type: Application
    Filed: September 3, 2012
    Publication date: October 23, 2014
    Applicant: Glytech, Inc.
    Inventors: Hirofumi Ochiai, Taiji Shimoda, Kazuhiro Fukae, Masatoshi Maeda, Keisuke Tazuru, Kenta Yoshida