Abstract: The present invention aims to provide a tissue regeneration substrate excellent in penetrability to cells as well as capable of effectively preventing cell leakage from the tissue regeneration substrate to accelerate tissue regeneration; and a method of producing the tissue regeneration substrate. The present invention relates to a tissue regeneration substrate including: a nonwoven fabric made of a bioabsorbable material, the tissue regeneration substrate having a laminated structure in which a layer containing a nonwoven fabric having an average pore size of 20 to 50 ?m and a layer containing a nonwoven fabric having an average pore size of 5 to 20 ?m are integrated.

Abstract: The present invention aims to provide a tissue regeneration substrate excellent in penetrability to cells as well as capable of effectively preventing cell leakage from the tissue regeneration substrate to accelerate tissue regeneration; and a method of producing the tissue regeneration substrate. The present invention relates to a tissue regeneration substrate including: a nonwoven fabric made of a bioabsorbable material, the tissue regeneration substrate having a laminated structure in which a layer containing a nonwoven fabric having an average pore size of 20 to 50 ?m and a layer containing a nonwoven fabric having an average pore size of 5 to 20 ?m are integrated.

Abstract: A belt reinforcing layer is disposed outwardly in the radial direction of a tire so as to reinforce the whole portion or the end portions of a tread portion. The belt reinforcing layer is formed by spirally winding a rubber-coated and narrow strip made of a fiber cord/cords around a tire. A pair of bead fillers are disposed directly above bead cores of a pair of bead portions. The cords of the belt reinforcing layer are made of organic fiber cords, and have a 2.7% or less elongation under load of 1.4g/d at the temperature of 50±5° C., and have a 1.5 to 6.0% elongation under load of 0.7g/d at the temperature of 170±5° C. The height L of each of the bead fillers corresponds to 20 to 60% of the cross sectional height T of a tire.

Abstract: A pneumatic radial tire comprises a radial carcass ply toroidally extending between a pair of bead cores, a stiffener disposed above each bead core between the carcass ply and its turnup portion, and a rubber chafer arranged outside the turnup portion, provided that a ratio of cross-sectional area of the stiffener to cross-sectional area of the rubber chafer is not more than 0.5. In this tire, a sidewall-reinforcing rubber layer having a JIS A hardness of not less than 80.degree. is arranged along the carcass ply in a region ranging from a crown portion of the carcass ply to the bead core.