Patents by Inventor Keith A. Hruska

Keith A. Hruska has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for prostate epithelial cell differentiation
    Publication number: 20040253207
    Abstract: Methods and compositions for treating prostate cancer by promoting prostate epithelial cell differentiation are described. Treatment methods involve administration of an active form of prostate-derived factor (PDF), or of an inactive PDF precursor, or of a combination of a proprotein convertase (PC) with a PDF precursor, to increase the biological activity of PDF in the subject and promote prostate epithelial cell differentiation.
    Type: Application
    Filed: November 7, 2003
    Publication date: December 16, 2004
    Applicant: Barnes-Jewish Hospital
    Inventors: Keith A. Hruska, Lala R. Chaudhary
  • Voltage-gated calcium channel and antisense oligonucleotides thereto
    Patent number: 5824550
    Abstract: An antisense oligonucleotide of 10 to 35 nucleotides in length that can hybridize with a region of the .alpha..sub.1 subunit of the SA-Cat channel gene DNA or mRNA is provided, together with pharmaceutical compositions containing and methods utilizing such antisense oligonucleotide.
    Type: Grant
    Filed: October 28, 1994
    Date of Patent: October 20, 1998
    Assignee: Barnes-Jewish Hopital
    Inventors: Keith A. Hruska, Peter A. Friedman, Elizabeth L. R. Barry, Randall L. Duncan