Patents by Inventor Keith A. McFarland

Keith A. McFarland has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10689636
    Abstract: The present invention relates to methods of increasing the activity of a polypeptide having cellulolytic enhancing activity, comprising: adding a soluble activating divalent metal cation to a composition comprising the polypeptide having cellulolytic enhancing activity, wherein the presence of the soluble activating divalent metal cation and the polypeptide having cellulolytic enhancing activity increases degradation or conversion of a cellulose-containing material by a cellulolytic enzyme composition compared to the polypeptide having cellulolytic enhancing activity without the soluble activating divalent metal cation. The present invention also relates to compositions, methods for degrading or converting a cellulose-containing material, and methods for producing a fermentation product.
    Type: Grant
    Filed: February 21, 2018
    Date of Patent: June 23, 2020
    Assignee: Novozymes, Inc.
    Inventors: Keith McFarland, Paul Harris
  • Publication number: 20200148730
    Abstract: The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Application
    Filed: December 17, 2019
    Publication date: May 14, 2020
    Applicant: Novozymes, Inc.
    Inventors: Kimberly Brown, Paul Harris, Elizabeth Zaretsky, Edward Re, Elena Vlasenko, Keith McFarland, Alfredo Lopez de Leon
  • Patent number: 10544195
    Abstract: The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: October 10, 2018
    Date of Patent: January 28, 2020
    Assignee: Novozymes, Inc.
    Inventors: Kimberly Brown, Paul Harris, Elizabeth Zaretsky, Edward Re, Elena Vlasenko, Keith McFarland, Alfredo Lopez de Leon
  • Patent number: 10513721
    Abstract: The invention relates to processes of multi-stage hydrolysis where different enzyme compositions are added in at least two stages of hydrolysis. In a first stage, a first enzyme composition of one or more cellulolytic enzymes and at least one of an oxidoreductase and an AA9 polypeptide having cellulolytic enhancing activity is added, followed by a latter stage in which a second enzyme composition comprising one or more cellulases is added. Also provided are processes for obtaining hydrolysis products and fermentation products using processes of the invention.
    Type: Grant
    Filed: March 11, 2016
    Date of Patent: December 24, 2019
    Assignee: Novozymes A/S
    Inventors: Jiyin Liu, James Michael Broering, Keith McFarland, Xin Li
  • Patent number: 10280201
    Abstract: The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: August 29, 2017
    Date of Patent: May 7, 2019
    Assignee: Novozymes, Inc.
    Inventors: Kimberly Brown, Paul Harris, Elizabeth Zaretsky, Edward Re, Elena Vlasenko, Keith McFarland, Alfredo Lopez de Leon
  • Publication number: 20190023751
    Abstract: The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Application
    Filed: October 10, 2018
    Publication date: January 24, 2019
    Applicant: Novozymes, Inc.
    Inventors: Kimberly Brown, Paul Harris, Elizabeth Zaretsky, Edward Re, Elena Vlasenko, Keith McFarland, Alfredo Lopez de Leon
  • Publication number: 20180237759
    Abstract: The present invention relates to cellulolytic compositions for degrading or converting cellulose-containing material and methods of producing and using the compositions.
    Type: Application
    Filed: April 17, 2018
    Publication date: August 23, 2018
    Applicant: Novozymes, Inc.
    Inventors: Sandra Merino, Keith McFarland, Joel Cherry, Sarah Teter
  • Publication number: 20180202011
    Abstract: The present invention relates to methods of inhibiting AA9 lytic polysaccharide monooxygenase catalyzed inactivation of an enzyme composition or a component thereof, methods for increasing production of an enzyme composition, and methods for stabilizing an enzyme composition.
    Type: Application
    Filed: September 2, 2016
    Publication date: July 19, 2018
    Applicant: Novozymes A/S
    Inventors: Keith McFarland, Ani Tejirian, Derek Akerhielm
  • Publication number: 20180187178
    Abstract: The present invention relates to methods of increasing the activity of a polypeptide having cellulolytic enhancing activity, comprising: adding a soluble activating divalent metal cation to a composition comprising the polypeptide having cellulolytic enhancing activity, wherein the presence of the soluble activating divalent metal cation and the polypeptide having cellulolytic enhancing activity increases degradation or conversion of a cellulose-containing material by a cellulolytic enzyme composition compared to the polypeptide having cellulolytic enhancing activity without the soluble activating divalent metal cation. The present invention also relates to compositions, methods for degrading or converting a cellulose-containing material, and methods for producing a fermentation product.
    Type: Application
    Filed: February 21, 2018
    Publication date: July 5, 2018
    Applicant: Novozymes, Inc.
    Inventors: Keith McFarland, Paul Harris
  • Patent number: 9969993
    Abstract: The present invention relates to cellulolytic compositions for degrading or converting cellulose-containing material and methods of producing and using the compositions.
    Type: Grant
    Filed: May 30, 2008
    Date of Patent: May 15, 2018
    Assignee: Novozymes, Inc.
    Inventors: Sandra Merino, Keith McFarland, Joel Cherry, Sarah Teter
  • Patent number: 9938513
    Abstract: The present invention relates to methods of increasing the activity of a polypeptide having cellulolytic enhancing activity, comprising: adding a soluble activating divalent metal cation to a composition comprising the polypeptide having cellulolytic enhancing activity, wherein the presence of the soluble activating divalent metal cation and the polypeptide having cellulolytic enhancing activity increases degradation or conversion of a cellulose-containing material by a cellulolytic enzyme composition compared to the polypeptide having cellulolytic enhancing activity without the soluble activating divalent metal cation. The present invention also relates to compositions, methods for degrading or converting a cellulose-containing material, and methods for producing a fermentation product.
    Type: Grant
    Filed: August 30, 2016
    Date of Patent: April 10, 2018
    Assignee: Novozymes, Inc.
    Inventors: Keith McFarland, Paul Harris
  • Publication number: 20180072779
    Abstract: The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Application
    Filed: August 29, 2017
    Publication date: March 15, 2018
    Applicant: Novozymes, Inc.
    Inventors: Kimberly Brown, Paul Harris, Elizabeth Zaretsky, Edward Re, Elena Vlasenko, Keith McFarland, Alfredo Lopez de Leon
  • Patent number: 9914946
    Abstract: The present invention relates to methods for degrading or converting a cellulose-containing material, comprising: treating the cellulose-containing material with an effective amount of a cellulolytic enzyme composition comprising a polypeptide having cellulolytic enhancing activity, and one or more (several) components selected from the group consisting of a CEL7 polypeptide having endoglucanase activity, a CEL12 polypeptide having endoglucanase activity, a CEL45 polypeptide having endoglucanase activity, a CEL7 polypeptide having cellobiohydrolase activity with a cellulose binding domain, and a CEL7 polypeptide having cellobiohydrolase activity without a cellulose binding domain. The present invention also relates to such cellulolytic enzyme compositions.
    Type: Grant
    Filed: April 10, 2017
    Date of Patent: March 13, 2018
    Assignee: Novozymes, Inc.
    Inventor: Keith McFarland
  • Publication number: 20180044706
    Abstract: The invention relates to processes of multi-stage hydrolysis where different enzyme compositions are added in at least two stages of hydrolysis. In a first stage, a first enzyme composition of one or more cellulolytic enzymes and at least one of an oxidoreductase and an AA9 polypeptide having cellulolytic enhancing activity is added, followed by a latter stage in which a second enzyme composition comprising one or more cellulases is added. Also provided are processes for obtaining hydrolysis products and fermentation products using processes of the invention.
    Type: Application
    Filed: March 11, 2016
    Publication date: February 15, 2018
    Applicant: Novozymes A/S
    Inventors: Jiyin Liu, James Michael Broering, Keith McFarland, Xin Li
  • Patent number: 9751916
    Abstract: The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: June 21, 2016
    Date of Patent: September 5, 2017
    Assignee: Novozymes, Inc.
    Inventors: Kimberly Brown, Paul Harris, Elizabeth Zaretsky, Edward Re, Elena Vlasenko, Keith McFarland, Alfredo Lopez de Leon
  • Publication number: 20170218413
    Abstract: The present invention relates to methods for degrading or converting a cellulose-containing material, comprising: treating the cellulose-containing material with an effective amount of a cellulolytic enzyme composition comprising a polypeptide having cellulolytic enhancing activity, and one or more (several) components selected from the group consisting of a CEL7 polypeptide having endoglucanase activity, a CEL12 polypeptide having endoglucanase activity, a CEL45 polypeptide having endoglucanase activity, a CEL7 polypeptide having cellobiohydrolase activity with a cellulose binding domain, and a CEL7 polypeptide having cellobiohydrolase activity without a cellulose binding domain. The present invention also relates to such cellulolytic enzyme compositions.
    Type: Application
    Filed: April 10, 2017
    Publication date: August 3, 2017
    Inventor: Keith McFarland
  • Patent number: 9631213
    Abstract: The present invention relates to methods for degrading or converting a cellulose-containing material, comprising: treating the cellulose-containing material with an effective amount of a cellulolytic enzyme composition comprising a polypeptide having cellulolytic enhancing activity, and one or more (several) components selected from the group consisting of a CEL7 polypeptide having endoglucanase activity, a CEL12 polypeptide having endoglucanase activity, a CEL45 polypeptide having endoglucanase activity, a CEL7 polypeptide having cellobiohydrolase activity with a cellulose binding domain, and a CEL7 polypeptide having cellobiohydrolase activity without a cellulose binding domain. The present invention also relates to such cellulolytic enzyme compositions.
    Type: Grant
    Filed: March 27, 2015
    Date of Patent: April 25, 2017
    Assignee: Novozymes, Inc.
    Inventor: Keith McFarland
  • Patent number: 9544271
    Abstract: An anonymous communication module that provides full conversational anonymous messaging and voice/video communication between two or more parties interacting over a wireless/landline network. An anonymous messaging module accepts an anonymous initiation message to a public address to trigger the start of an anonymous voice/video conversation between a message originator and a message recipient. An anonymous communication module performs intercept and address substitution on a message and/or voice/video call transmitted between two or more parties via an anonymous communication service. The anonymous communication module substitutes a real address in the source field of an intercepted message and/or voice/video call, with an anonymous address mapped to that real address, and substitutes an anonymous address in the destination field of an intercepted message and/or voice/video call with a real address mapped to that anonymous address.
    Type: Grant
    Filed: September 11, 2012
    Date of Patent: January 10, 2017
    Assignee: Telecommunication Systems, Inc.
    Inventors: Keith McFarland, Vishal Jain
  • Publication number: 20160369253
    Abstract: The present invention relates to methods of increasing the activity of a polypeptide having cellulolytic enhancing activity, comprising: adding a soluble activating divalent metal cation to a composition comprising the polypeptide having cellulolytic enhancing activity, wherein the presence of the soluble activating divalent metal cation and the polypeptide having cellulolytic enhancing activity increases degradation or conversion of a cellulose-containing material by a cellulolytic enzyme composition compared to the polypeptide having cellulolytic enhancing activity without the soluble activating divalent metal cation. The present invention also relates to compositions, methods for degrading or converting a cellulose-containing material, and methods for producing a fermentation product.
    Type: Application
    Filed: August 30, 2016
    Publication date: December 22, 2016
    Inventors: Keith McFarland, Paul Harris
  • Patent number: 9479503
    Abstract: Authenticating cloud computing enabling secure services (ACCESS) offloads “client authentication” activity onto a third-party authenticating cloud computing enabling secure services (ACCESS) node. Instead of having a client device authenticate itself directly to a network server, the client device instead authenticates itself to a third-party authenticating cloud computing enabling secure services (ACCESS) node. The authenticating cloud computing enabling secure services (ACCESS) node then provides credentials that are used by the client device to communicate directly with the server (and utilize the service) without any further authentication being necessary.
    Type: Grant
    Filed: December 16, 2015
    Date of Patent: October 25, 2016
    Assignee: Telecommunications Systems, Inc.
    Inventors: John L. Griffin, Keith A. McFarland, William P. Wells