Abstract: A reusable face mask with a foam face seal to protect against transmission of airborne pathogens. The face mask uses an easily interchangeable, readily available, non-proprietary, standard filter. It has a section specifically designed to mitigate the fogging of glasses, and has a user-interchangeable strap/harness system.

Abstract: A reusable face mask with a foam face seal to protect against transmission of airborne pathogens. The face mask uses an easily interchangeable, readily available, non-proprietary, standard filter. It has a section specifically designed to mitigate the fogging of glasses, and has a user-interchangeable strap/harness system.

Abstract: A system for reducing contaminants in body of water is shown and described. The system has a first land mass located within a body of water. A sediment trap, located on the floor of the body of water, is configured to collect sediment. Enclosed within the first land mass is a tussock mass area, surrounding a central area, and configured for collecting sediment and building a second land mass. The central area of the system is configured for removing contaminants from sediment. Sediment is moved from the sediment trap to the central area by a first ingress conduit and a pumping system. Filtered water migrates from the central area to outside the first land mass via an egress conduit; contaminated sediment is sequestered in the central area enclosed by the tussock mass area.

Abstract: Compounds of the formula (I): wherein A and B together represent an optionally substituted, fused aromatic ring; X can be NRX or CRXRY; if X=NRX then n is 1 or 2 and if X=CRXRY then n is 1; RX is selected from the group consisting of H, optionally substituted C1-20 alkyl, C5-20 aryl, C3-20 heterocyclyl, amido, thioamido, ester, acyl, and sulfonyl groups; RY is selected from H, hydroxy, amino; or RX and RY may together form a spiro-C3-7 cycloalkyl or heterocyclyl group; RC1 and RC2 are both hydrogen, or when X is CRXRY, RC1, RC2, RX and RY, together with the carbon atoms to which they are attached, may form an optionally substituted fused aromatic ring; and R1 is selected from H and halo.

Abstract: A method of manufacturing a tri-stage assembly is described herein. The method includes attaching a first microactuator and a second microactuator to a trace gimbal to a flexure during a PZT on flexure process (POF). The first microactuator is located at a distal end of the flexure and the second microactuator located at a proximal end of the flexure. The method also includes welding the trace gimbal to a baseplate, and a load beam to secure the trace gimbal including the first microactuator and the second microactuator.

Abstract: Compounds of the formula (I): wherein A and B together represent an optionally substituted, fused aromatic ring; X can be NRX or CRXRY; if X?NRX then n is 1 or 2 and if X?CRXRY then n is 1; RX is selected from the group consisting of H, optionally substituted C1-20 alkyl, C5-20 aryl, C3-20 heterocyclyl, amido, thioamido, ester, acyl, and sulfonyl groups; RY is selected from H, hydroxy, amino; or RX and RY may together form a spiro-C3-7 cycloalkyl or heterocyclyl group; RC1 and RC2 are both hydrogen, or when X is CRXRY, RC1, RC2, RX and RY, together with the carbon atoms to which they are attached, may form an optionally substituted fused aromatic ring; and R1 is selected from H and halo.

Abstract: A method of manufacturing a tri-stage assembly is provided. The method includes attaching a first microactuator and a second microactuator to a trace gimbal to a flexure during a PZT on flexure process (POF). The first microactuator is located at a distal end of the flexure and the second microactuator located at a proximal end of the flexure. The method also includes welding the trace gimbal to a baseplate, and a load beam to secure the trace gimbal including the first microactuator and the second microactuator.

Abstract: A system for reducing contaminants in body of water is shown and described. The system has a first land mass located within a body of water. A sediment trap, located on the floor of the body of water, is configured to collect sediment. Enclosed within the first land mass is a tussock mass area, surrounding a central area, and configured for collecting sediment and building a second land mass. The central area of the system is configured for removing contaminants from sediment. Sediment is moved from the sediment trap to the central area by a first ingress conduit and a pumping system. Filtered water migrates from the central area to outside the first land mass via an egress conduit; contaminated sediment is sequestered in the central area enclosed by the tussock mass area.

Abstract: The invention relates to novel compounds of formula I which are inhibitors of deubiquitylating enzymes (DUBs) and/or desumoylating enzymes. In particular, the invention relates to the inhibition of ubiquitin C-terminal hydrolase 7 or ubiquitin specific peptidase 7 (USP7). The invention further relates to methods for the preparation of these compounds and to their use in the treatment of cancer.

Abstract: Flexible control surfaces and related methods are disclosed. Example apparatus disclosed herein include an airfoil including a skin, the skin having perforations filled with an elastomer to increase a flexibility of the skin; and a flexible core adjacent the perforations of the skin to support the skin.

Abstract: Compounds of the formula (I): wherein A and B together represent an optionally substituted, fused aromatic ring; X can be NRX or CRXRY; if X?NRX then n is 1 or 2 and if X?CRXRY then n is 1; RX is selected from the group consisting of H, optionally substituted C1-20 alkyl, C5-20 aryl, C3-20 heterocyclyl, amido, thioamido, ester, acyl, and sulfonyl groups; RY is selected from H, hydroxy, amino; or RX and RY may together form a spiro-C3-7 cycloalkyl or heterocyclyl group; RC1 and RC2 are both hydrogen, or when X is CRXRY, RC1, RC2, RX and RY, together with the carbon atoms to which they are attached, may form an optionally substituted fused aromatic ring; and R1 is selected from H and halo.

Abstract: Compounds of the formula (I): wherein A and B together represent an optionally substituted, fused aromatic ring; X can be NRX or CRXRY; if X?NRX then n is 1 or 2 and if X?CRXRY then n is 1; RX is selected from the group consisting of H, optionally substituted C1-20 alkyl, C5-20 aryl, C3-20 heterocyclyl, amido, thioamido, ester, acyl, and sulfonyl groups; RY is selected from H, hydroxy, amino; or RX and RY may together form a spiro-C3-7 cycloalkyl or heterocyclyl group; RC1 and RC2 are both hydrogen, or when X is CRXRY, RC1, RC2, RX and RY, together with the carbon atoms to which they are attached, may form an optionally substituted fused aromatic ring; and R1 is selected from H and halo.

Abstract: An apparatus includes a superstructure including cylindrical vessel with a conical bottom section and an opening near the base of the cone; an air assisted puffer device near the base of the cone; an air blower attached near the base of the cone, wherein the air blower is configured to produce air velocities of at least about 40 ft/min; a gently sweeping elbow attached after the blower exit; and a hatch fitted to the top of the vessel that allows for a funnel to be connected to the tank thereby allowing bulk barite powder to be loaded into the top of the tank from bulk bags. A barite powder blend including: a blend of barite particles with a size of about 1 micron and barite particles with a size of at least about 325 mesh, wherein the D50 of the blend is not greater than about 325 mesh.

Abstract: The invention relates to novel compounds of formula I which are inhibitors of deubiquitylating enzymes (DUBs) and/or desumoylating enzymes. In particular, the invention relates to the inhibition of ubiquitin C-terminal hydrolase 7 or ubiquitin specific peptidase 7 (USP7). The invention further relates to methods for the preparation of these compounds and to their use in the treatment of cancer.

Abstract: Flexible control surfaces and related methods are disclosed. Example apparatus disclosed herein include an airfoil including a skin, the skin having perforations filled with an elastomer to increase a flexibility of the skin; and a flexible core adjacent the perforations of the skin to support the skin.

Abstract: Compounds of the formula (I): wherein A and B together represent an optionally substituted, fused aromatic ring; X can be NRX or CRXRY; if X?NRX then n is 1 or 2 and if X?CRXRY then n is 1; RX is selected from the group consisting of H, optionally substituted C1-20 alkyl, C5-20 aryl, C3-20 heterocyclyl, amido, thioamido, ester, acyl, and sulfonyl groups; RY is selected from H, hydroxy, amino; or RX and RY may together form a spiro-C3-7 cycloalkyl or heterocyclyl group; RC1 and RC2 are both hydrogen, or when X is CRXRY, RC1, RC2, RX and RY, together with the carbon atoms to which they are attached, may form an optionally substituted fused aromatic ring; and R1 is selected from H and halo.

Abstract: A system and device for controlling a display are disclosed. Data is examined, which correspond to an image to be shown with the display. Upon determining that said data comprise a critical item corresponding to an element of the image, the critical item is shown with an uncluttered view. Non-critical items corresponding to elements of the image are attempted to be shown as well, such that the critical item is not obscured and the image remains uncluttered.

Abstract: Compounds of the formula (I): wherein A and B together represent an optionally substituted, fused aromatic ring; X can be NRX or CRXRY; if X=NRX then n is 1 or 2 and if X=CRXRY then n is 1; RX is selected from the group consisting of H, optionally substituted C1-20 alkyl, C5-20 aryl, C3-20 heterocyclyl, amido, thioamido, ester, acyl, and sulfonyl groups; RY is selected from H, hydroxy, amino; or RX and RY may together form a spiro-C3-7 cycloalkyl or heterocyclyl group; RC1 and RC2 are both hydrogen, or when X is CRXRY, RC1, RC2, RX and RY, together with the carbon atoms to which they are attached, may form an optionally substituted fused aromatic ring; and R1 is selected from H and halo.

Abstract: An injection-molded plastic roofing membrane plate includes a body and multiple cleats. The cleats extend from a bottom surface of the body. Each of the cleats has a rounded terminal end with a rounded terminal surface. The rounded terminal surfaces make surface-to-surface abutment with an underlying membrane in installation. The rounded terminal surfaces reduce wear on the underlying membrane that may otherwise occur.

Abstract: An apparatus includes a superstructure including cylindrical vessel with a conical bottom section and an opening near the base of the cone; an air assisted puffer device near the base of the cone; an air blower attached near the base of the cone, wherein the air blower is configured to produce air velocities of at least about 40 ft/min; a gently sweeping elbow attached after the blower exit; and a hatch fitted to the top of the vessel that allows for a funnel to be connected to the tank thereby allowing bulk barite powder to be loaded into the top of the tank from bulk bags. A barite powder blend including: a blend of barite particles with a size of about 1 micron and barite particles with a size of at least about 325 mesh, wherein the D50 of the blend is not greater than about 325 mesh.