Abstract: Disclosed herein are forms of L-ornithine phenyl acetate and methods of making the same. A crystalline form may, in some embodiments, be Forms I, II, III and V, or mixtures thereof. The crystalline forms may be formulated for treating subjects with liver disorders, such as hepatic encephalopathy. Accordingly, some embodiments include formulations and methods of administering L-ornithine phenyl acetate.

Abstract: Disclosed herein are methods of treating and/or preventing portal hypertension and/or restoring liver function using L-ornithine phenylacetate.

Abstract: Disclosed herein are crystalline forms of L-ornithine phenyl acetate and methods of making the same. The crystalline form may, in some embodiments, be Forms I, II, III and V, or mixtures thereof. The crystalline forms may be formulated for treating subjects with liver disorders, such as hepatic encephalopathy. Accordingly, some embodiments include formulations and methods of administering L-ornithine phenyl acetate.

Abstract: A lighting fixture (1010) has a fluorescent tube (1012) and a plurality of emitters (1022-1032). A color sensor (1016) detects light that has been totally internally reflected within a diffuser (1014) and provides a color feedback signal to a feedback control circuit (1020) to control the light output from the fixture (1012).

Abstract: Diffractive patterns are disposed on a MEMS substrate in the gaps between the MEMS micromirrors to reduce backreflection of light leaking through the gaps and reflected by the MEMS substrate. The diffractive patterns are silicon surface-relief diffraction gratings or silicon oxide gratings on silicon substrate. Sub-wavelength gratings are used to suppress higher orders of diffraction; 50% duty cycle surface relief gratings on a substrate having index of refraction close to 3 are used to suppress both reflected and transmitted zero orders of diffraction simultaneously. The gratings have lines running parallel or at a slight angle to the gaps, to prevent the diffracted light from re-entering the gaps.

Abstract: Disclosed herein are crystalline forms of L-ornithine phenyl acetate and methods of making the same. The crystalline form may, in some embodiments, be Forms I, II, III and V, or mixtures thereof. The crystalline forms may be formulated for treating subjects with liver disorders, such as hepatic encephalopathy. Accordingly, some embodiments include formulations and methods of administering L-ornithine phenyl acetate.

Abstract: A system for controlling solid state lighting comprises a source (1) to supply any one of a range of AC or DC voltages to a plurality of light strings (3, 4, 5). The source (1) includes a power factor correction circuit 14 for controlling the power factor to the system and a separate transformer (15, 16, 17) for each light string (3, 4, 5). The current that can pass through each LED string (3, 4 and 5) is independently limited by each corresponding LED driver circuit (6, 19 and 20). The current through each LED string (3, 4 and 5) can be modified according to a feedback monitor system (18, 21 and 22) that measures parameters such as LED characteristics, forward current, temperature, and LED output intensity/colour.

Abstract: This document provides methods and materials related to assessing male mammals (e.g., humans) with prostate cancer. For example, methods and materials for predicting (1) which patients, at the time of PSA reoccurrence, will later develop systemic disease, (2) which patients, at the time of retropubic radial prostatectomy, will later develop systemic disease, and (3) which patients, at the time of systemic disease, will later die from prostate cancer are provided.

Abstract: Diffractive patterns are disposed on a MEMS substrate in the gaps between the MEMS micromirrors to reduce backreflection of light leaking through the gaps and reflected by the MEMS substrate. The diffractive patterns are silicon surface-relief diffraction gratings or silicon oxide gratings on silicon substrate. Sub-wavelength gratings are used to suppress higher orders of diffraction; 50% duty cycle surface relief gratings on a substrate having index of refraction close to 3 are used to suppress both reflected and transmitted zero orders of diffraction simultaneously. The gratings have lines running parallel or at a slight angle to the gaps, to prevent the diffracted light from re-entering the gaps.

Abstract: The present invention provides a method of synthesizing phosphoramidite linkers that are useful for the production of synthesizing two or more oligonucleotides in tandem. The inventive linker has the following desirable properties: (i) enhanced stability to alkali conditions versus the linkers previously published, (ii) cleaves to produce 5? and 3? ends that are fully biologically compatible, (iii) cleaves completely under conditions that are already used in cleavage/deprotection processes so it is fully compatible with conditions that are common in laboratories and does not require additives that necessitate further purification after cleavage, (iv) integrates easily onto commercially available synthesizers because it is compatible with standard coupling chemistry, and (v) is compatible with DNA, RNA, forward, reverse, and LNA, synthesis chemistries. In addition, the inventive linkers may be coupled to a solid support. Thus, the inventive linkers provide a significant advancement in the state of the art.

Abstract: The present invention provides phosphoramidite linkers that are useful for the production of synthesizing two or more oligonucleotides in tandem. The inventive linkers have the following desirable properties: (i) enhanced stability to alkali conditions versus the linkers previously published, (ii) cleave to produce 5? and 3? ends that are fully biologically compatible, (iii) cleave completely under conditions that are already used in cleavage/deprotection processes so they are fully compatible with conditions that are common in laboratories and do not require additives that necessitate further purification after cleavage, (iv) integrate easily onto commercially available synthesizers because they are compatible with standard coupling chemistry, and (v) are compatible with DNA, RNA, forward, reverse, and synthesis chemistries. In addition, the inventive linkers may be coupled to a solid support. Thus, the inventive linkers provide a significant advancement in the state of the art.

Abstract: A climbing wall assembly having wall panels to form free-standing, wall-mounted or a combination climbing wall assembly. The climbing wall assembly further has novel handhold structures constructed to be used with removable elements to form a challenge course.

Abstract: A lighting fixture (1010) has a fluorescent tube (1012) and a plurality of emitters (1022-1032). A colour sensor (1016) detects light that has been totally internally reflected within a diffuser (1014) and provides a colour feedback signal to a feedback control circuit (1020) to control the light output from the fixture (1012).

Abstract: Disclosed herein is the use of adsorbent carbon microspheres for the treatment of intestinal bacterial infections. The infections include infection with Escherichia coli, Shigella dysenteriae, Vibrio cholerae, and Clostridium difficile. The adsorbent carbon microspheres serve to adsorb or bind toxins produced by the bacteria.

Abstract: The present invention provides the identification and combination of genes that are expressed in tumors that are responsive to a given therapeutic agent and whose combined expression can be used as an index that correlates with responsiveness to that therapeutic agent. One or more of the genes of the present invention may be used as markers (or surrogate markers) to identify tumors that are likely to be successfully treated by that agent or class of agents such as hormonal or endocrine treatment.

Abstract: A pliable single use liquid container and dispensing device for delivery of a precise amount of orally administered liquids across a broad range of viscosities is provide with the container being formed of generally opposed pliable sheets, a first seal joining the first and second pliable sheets and partially defining a liquid-containing chamber, a second seal joining the first and second pliable sheets and partially defining a pressure relieving chamber adjacent to the liquid-containing chamber, a boundary seal joining the first and second pliable sheets between the liquid-containing chamber and the pressure relieving chamber, a precisely measured single dose volume of fluent liquid disposed within the liquid-containing chamber, the boundary seal being lighter than the first and second seals so that upon application of pressure to the liquid in the liquid-containing chamber the fluid transfer region seal opens to permit the liquid to flow from the liquid-containing chamber into the pressure relieving chamber

Abstract: An apparatus, data structures, and method are provided for prioritizing data transmissions within a network. As applied to a switching station in a network, the method prioritizes transmissions from the network to determine which packets should be transmitted from the switching station first when multiple packets are routed to the same outgoing port of the switching station. A packet prioritization station is provided, preferably as an add-on to the switching station. The packet prioritization station has a cache in which the destination address of each incoming packet is associated with every origin from which it has received a transmission within a certain time period. The packet prioritization station operates to give priority to transmissions to those destinations that have a higher number of associated origins. Thus, packets that are probably en route to time-critical users or groups of users will be sent before those that are less time-sensitive.

Abstract: A system comprising a transmitter periodically transmitting a packet via electromagnetic radiation. The packet may be encoded with information and have a length measured in time. The system may further include a receiver comprising an antenna converting incident electromagnetic radiation to an analog electrical current, an analog-to-digital converter receiving the analog electrical current and producing a digital representation thereof, and first and second buffers. Each of the buffers may have a capacity of at least two times the length of the packet. The first and second buffers may store respective first and second copies of the digital representation. The first copy may be offset in time from the second copy by at least the length of the packet.

Abstract: An amusement ride assembly 100 includes a rotatable endless loop cable 101 spanning between end stations 102, 103 and a drive system operable to rotate the loop cable 101. A passenger carrier 104 is suspended from the cable and includes a roller mechanism 300 to enable the passenger carrier to free-roll along the cable 101 and an associated clamping mechanism 400 to alternatively fix the passenger carrier 104 to the cable 101. A control system may control the drive system and to enable actuation of the clamping mechanism 400 to fix the passenger carrier 104 to the cable 101 when the carrier 104 is at a position along the cable remote from the end stations 102, 103.