Patents by Inventor Keith Andrew Newton GRAHAM

Keith Andrew Newton GRAHAM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BORON CONTAINING PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF
    Publication number: 20240132525
    Abstract: The present disclosure describes boron containing pyrimidine compounds, or their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and their medical uses. The compounds of the present disclosure have activity as Janus kinase (JAK) inhibitors and are useful in the in the treatment or control of inflammation, auto-immune diseases, cancer, and other disorders and indications where modulation of JAK would be desirable. Also described are methods of treating inflammation, auto-immune diseases, cancer, and other conditions that are susceptible to the inhibition of a Janus kinase by administering a compound herein described.
    Type: Application
    Filed: June 16, 2023
    Publication date: April 25, 2024
    Inventors: ALAN LONG, SHON R. PULLEY, KEITH ANDREW NEWTON GRAHAM, CHUNLIANG LIU, YASHEEN ZHOU
  • Boron containing pyrazole compounds, compositions comprising them, methods and uses thereof
    Patent number: 11827657
    Abstract: The present invention describes novel boron containing pyrazole compounds, or their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and their medical uses. The compounds of the invention have activity as Janus kinase (JAK) inhibitors and are useful in the in the treatment or control of inflammation, auto-immune diseases, cancer, and other disorders and indications where modulation of JAK would be desirable. Also described are methods of treating inflammation, auto-immune diseases, cancer, and other conditions that are susceptible to the inhibition of a Janus kinase by administering a compound herein described.
    Type: Grant
    Filed: December 13, 2021
    Date of Patent: November 28, 2023
    Assignees: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC., BORAH, INC.
    Inventors: Alan Long, Chun Yu Liu, Chunliang Liu, Yasheen Zhou, Shon R. Pulley, Keith Andrew Newton Graham
  • BORON CONTAINING PYRAZOLE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF
    Publication number: 20220194965
    Abstract: The present invention describes novel boron containing pyrazole compounds, or their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and their medical uses. The compounds of the invention have activity as Janus kinase (JAK) inhibitors and are useful in the in the treatment or control of inflammation, auto-immune diseases, cancer, and other disorders and indications where modulation of JAK would be desirable. Also described are methods of treating inflammation, auto-immune diseases, cancer, and other conditions that are susceptible to the inhibition of a Janus kinase by administering a compound herein described.
    Type: Application
    Filed: December 13, 2021
    Publication date: June 23, 2022
    Inventors: Alan LONG, Chun Yu LIU, Chunliang LIU, Yasheen ZHOU, Shon R. PULLEY, Keith Andrew Newton GRAHAM