Patents by Inventor Keith B. Elkon

Keith B. Elkon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Levels of BCMA protein expression on B cells and use in methods of treating systemic lupus erythematosus
    Patent number: 9725506
    Abstract: The present invention provides a method of measuring the levels of BCMA in a biological sample, specifically upon the B cell surface. The diagnostic assays are useful in predicting an individual's likelihood of developing or currently suffering from an autoimmune disease, such as SLE, and for methods for treating an individual clinically diagnosed with an autoimmune disease. This diagnostic test serves to predict a patient's likelihood to respond to a specific drug treatment, in particular treatment with BLyS antagonists, either singly or in combination with other immune suppressive drugs.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: August 8, 2017
    Assignees: ZYMOGENETICS, INC., UNIVERSITY OF WASHINTON
    Inventors: Stacey R. Dillon, Jane A. Gross, Keith B. Elkon
  • LEVELS OF BCMA PROTEIN EXPRESSION ON B CELLS AND USE IN DIAGNOSTIC METHODS
    Publication number: 20140220014
    Abstract: The present invention provides a method of measuring the levels of BCMA in a biological sample, specifically upon the B cell surface. The diagnostic assays are useful in predicting an individual's likelihood of developing or currently suffering from an autoimmune disease, such as SLE, and for methods for treating an individual clinically diagnosed with an autoimmune disease.
    Type: Application
    Filed: February 28, 2014
    Publication date: August 7, 2014
    Applicants: University of Washington, ZymoGenetics, Inc.
    Inventors: Stacey R. Dillon, Jane A. Gross, Keith B. Elkon
  • LEVELS OF BCMA PROTEIN EXPRESSION ON B CELLS AND USE IN DIAGNOSTIC METHODS
    Publication number: 20090325196
    Abstract: The present invention provides a method of measuring the levels of BCMA in a biological sample, specifically upon the B cell surface. The diagnostic assays are useful in predicting an individual's likelihood of developing or currently suffering from an autoimmune disease, such as SLE, and for methods for treating an individual clinically diagnosed with an autoimmune disease.
    Type: Application
    Filed: April 24, 2009
    Publication date: December 31, 2009
    Applicants: ZymoGenetics, Inc., University of Washington
    Inventors: Stacey R. Dillon, Jane A. Gross, Keith B. Elkon
  • Levels of BCMA protein expression on B cells and use in methods of treating systemic lupus erythematosus
    Patent number: RE48370
    Abstract: The present invention provides a method of measuring the levels of BCMA in a biological sample, specifically upon the B cell surface. The diagnostic assays are useful in predicting an individual's likelihood of developing or currently suffering from an autoimmune disease, such as SLE, and for methods for treating an individual clinically diagnosed with an autoimmune disease. This diagnostic test serves to predict a patient's likelihood to respond to a specific drug treatment, in particular treatment with BLyS antagonists, either singly or in combination with other immune suppressive drugs.
    Type: Grant
    Filed: October 4, 2018
    Date of Patent: December 29, 2020
    Assignees: ZYMOGENETICS, INC., UNIVERSITY OF WASHINGTON
    Inventors: Stacey R. Dillon, Jane A. Gross, Keith B. Elkon