Patents by Inventor Keith Bauer

Keith Bauer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DNA POLYMERASES WITH INCREASED 3'-MISMATCH DISCRIMINATION
    Publication number: 20180142220
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Application
    Filed: January 5, 2018
    Publication date: May 24, 2018
    Inventors: Fred Reichert, Keith Bauer, Thomas W. Myers
  • DNA POLYMERASES WITH IMPROVED ACTIVITY
    Publication number: 20180135033
    Abstract: Disclosed are DNA polymerases having increased reverse transcriptase efficiency relative to a corresponding, unmodified polymerase. The polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the DNA polymerases.
    Type: Application
    Filed: January 4, 2018
    Publication date: May 17, 2018
    Inventors: Keith Bauer, Thomas W. Myers, Shawn Suko
  • DNA POLYMERASES WITH INCREASED 3'-MISMATCH DISCRIMINATION
    Publication number: 20180135034
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Application
    Filed: January 4, 2018
    Publication date: May 17, 2018
    Inventors: Keith Bauer, Fred Reichert, Thomas W. Myers
  • DNA POLYMERASES WITH INCREASED 3'-MISMATCH DISCRIMINATION
    Publication number: 20180119116
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Application
    Filed: November 6, 2017
    Publication date: May 3, 2018
    Inventors: Fred REICHERT, Keith BAUER, Thomas W. MYERS
  • DNA POLYMERASES WITH INCREASED 3'-MISMATCH DISCRIMINATION
    Publication number: 20180119117
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Application
    Filed: November 7, 2017
    Publication date: May 3, 2018
    Inventors: Fred REICHERT, Keith BAUER, Thomas W. MYERS
  • DNA POLYMERASES WITH INCREASED 3'-MISMATCH DISCRIMINATION
    Publication number: 20180112196
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Application
    Filed: November 22, 2017
    Publication date: April 26, 2018
    Inventors: Fred REICHERT, Keith BAUER, Thomas W. MYERS
  • DNA polymerases with improved activity
    Patent number: 9951320
    Abstract: Disclosed are DNA polymerases having increased reverse transcriptase efficiency relative to a corresponding, unmodified polymerase. The polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the DNA polymerases.
    Type: Grant
    Filed: July 28, 2016
    Date of Patent: April 24, 2018
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Keith Bauer, Thomas W. Myers, Shawn Suko
  • DNA polymerases with increased 3?-mismatch discrimination
    Patent number: 9902944
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Grant
    Filed: February 9, 2016
    Date of Patent: February 27, 2018
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Fred Reichert, Keith Bauer, Thomas W. Myers
  • DNA polymerases with increased 3?-mismatch discrimination
    Patent number: 9896669
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Grant
    Filed: February 9, 2016
    Date of Patent: February 20, 2018
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Fred Reichert, Keith Bauer, Thomas W. Myers
  • DNA polymerases with increased 3?-mismatch discrimination
    Patent number: 9896670
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Grant
    Filed: April 25, 2016
    Date of Patent: February 20, 2018
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Keith Bauer, Fred Reichert, Thomas W. Myers
  • DNA POLYMERASES WITH INCREASED 3'-MISMATCH DISCRIMINATION
    Publication number: 20180044648
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Application
    Filed: August 16, 2017
    Publication date: February 15, 2018
    Inventors: Fred REICHERT, Keith BAUER, Thomas W. MYERS
  • DNA polymerases with improved activity
    Patent number: 9890366
    Abstract: Disclosed are DNA polymerases having increased reverse transcriptase efficiency relative to a corresponding, unmodified polymerase. The polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the DNA polymerases.
    Type: Grant
    Filed: July 29, 2016
    Date of Patent: February 13, 2018
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Keith Bauer, Thomas W. Myers, Shawn Suko
  • DNA polymerases with increased 3?-mismatch discrimination
    Patent number: 9879237
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Grant
    Filed: April 25, 2016
    Date of Patent: January 30, 2018
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Keith Bauer, Fred Reichert, Thomas W. Myers
  • DNA POLYMERASES WITH INCREASED 3'-MISMATCH DISCRIMINATION
    Publication number: 20180023063
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Application
    Filed: August 10, 2017
    Publication date: January 25, 2018
    Inventors: Fred REICHERT, Keith BAUER, Thomas W. MYERS
  • DNA POLYMERASES WITH IMPROVED ACTIVITY
    Publication number: 20180010106
    Abstract: Disclosed are DNA polymerases having increased reverse transcriptase efficiency relative to a corresponding, unmodified polymerase. The polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the DNA polymerases.
    Type: Application
    Filed: July 24, 2017
    Publication date: January 11, 2018
    Inventors: Keith Bauer, Thomas W. Myers, Fred Reichert, Shawn Suko
  • DNA POLYMERASES WITH IMPROVED ACTIVITY
    Publication number: 20180010107
    Abstract: Provided are DNA polymerases having increased reverse transcriptase efficiency relative to a corresponding, unmodified polymerase. The polymerases are useful in a variety of primer extension methods. Also provided are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the DNA polymerases.
    Type: Application
    Filed: September 20, 2017
    Publication date: January 11, 2018
    Inventors: Keith BAUER, Thomas W. MYERS, Shawn SUKO
  • DNA polymerases with increased 3?-mismatch discrimination
    Patent number: 9856463
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Grant
    Filed: January 15, 2016
    Date of Patent: January 2, 2018
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Fred Reichert, Keith Bauer, Thomas W. Myers
  • DNA POLYMERASES AND RELATED METHODS
    Publication number: 20170369856
    Abstract: Disclosed are mutant DNA polymerases having improved extension rates relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Application
    Filed: July 6, 2017
    Publication date: December 28, 2017
    Inventors: Keith A. BAUER, Ellen FISS, David Harrow GELFAND, Edward S. SMITH, Shawn SUKO, Thomas W. MYERS
  • DNA polymerases with increased 3?-mismatch discrimination
    Patent number: 9840698
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Grant
    Filed: April 25, 2016
    Date of Patent: December 12, 2017
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Fred Reichert, Keith Bauer, Thomas W. Myers
  • DNA polymerases with increased 3?-mismatch discrimination
    Patent number: 9834761
    Abstract: Disclosed are mutant DNA polymerases having increased 3?-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
    Type: Grant
    Filed: February 9, 2016
    Date of Patent: December 5, 2017
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Fred Reichert, Keith Bauer, Thomas W. Myers