Patents by Inventor Keith BRUCE

Keith BRUCE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12286423
    Abstract: The invention provides compounds of Formula (I): as described herein, along with pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds, and methods to use these compounds, salts and compositions for treating viral infections.
    Type: Grant
    Filed: April 20, 2021
    Date of Patent: April 29, 2025
    Assignees: Novartis AG, Katholieke Universiteit Leuven, Korea Research Institute of Chemical Technology
    Inventors: Johan Neyts, Daniel Poon, Keith Bruce Pfister, Young-Sik Jung, Soo Bong Han, Yashwardhan R. Malpani, Prashant Chakrasali, Bishyajit Kumar Biswas, Chong-Kyo Lee, Chonsaeng Kim, Jin Soo Shin, Hae Soo Kim
  • Patent number: 12269950
    Abstract: A composition and a method for preparing a polymer composite article. The composition comprises (A) a filler in an amount of from 10 to 90 wt. The composition also comprises (B) a polymer in an amount of from 10 to 90 wt. %, wherein the (B) polymer is selected from polyolefins, polyamides, polyesters, or combinations thereof. Further, the composition comprises (C) an organopolysiloxane in an amount of from greater than 0 to 10 wt. %; the (C) organopolysiloxane having at least one silicon-bonded hydroxyl group and a viscosity of from 1,000 to 60,000 mPa·s at 25° C. The ranges for components (A)-(C) arc based on the total weight of components (A), (B) and (C) in the composition.
    Type: Grant
    Filed: December 6, 2023
    Date of Patent: April 8, 2025
    Assignees: DOW SILICONES CORPORATION, DOW GLOBAL TECHNOLOGIES LLC
    Inventors: Keith Bruce, Igor Chorvath, Marc-Andre Courtemanche, Jon V. Degroot, Jr., Sean Gaal, Craig Gross, James Keenihan, Shawn Mealey, Scott Miller, Tom Parsons, Andrew Schlader, Cristina Serrat, Lauren Tonge
  • Publication number: 20250090491
    Abstract: This disclosure provides compounds of Formula (I) as described herein, along with pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds, and methods to use these compounds, salts and compositions for treating viral infections.
    Type: Application
    Filed: August 7, 2024
    Publication date: March 20, 2025
    Inventors: Johan NEYTS, Daniel POON, Keith Bruce PFISTER, Young-Sik JUNG, Soo Bong HAN, Yashwardhan R. MALPANI, Prashant CHAKRASALI, Sang-Ho LEE, Chong-Kyo LEE, Chonsaeng KIM, Jin Soo SHIN, Hae Soo KIM
  • Publication number: 20250092036
    Abstract: The invention relates to compounds which modulate the activity of ERK. The present invention also relates to processes for the preparation of said compounds, pharmaceutical compositions comprising said compounds, and use of said compounds in the treatment of conditions, diseases and disorders mediated by ERK.
    Type: Application
    Filed: August 12, 2024
    Publication date: March 20, 2025
    Inventors: Erich W. BAUM, Thomas A. DINEEN, JR., Jonathan Edward HEMPEL, Matthew James HESSE, Robert KOENIG, Matthew James LAMARCHE, Jay Francis LARROW, Ruowei MO, Henrik MOEBITZ, Rukundo NTAGANDA, Keith Bruce PFISTER, Martin SENDZIK, Colin Keith SKEPPER, Joseph WZOREK, JR., Frédéric ZECRI
  • Patent number: 12215233
    Abstract: A polydiorganosiloxane is useful in a composition and a method for preparing a wood plastic composite article. The wood plastic composite article is useful as a building material. The polydiorganosiloxane may be added to the composition in liquid form or may form part of a solid carrier component used to make the wood plastic composite article.
    Type: Grant
    Filed: October 6, 2023
    Date of Patent: February 4, 2025
    Assignee: Dow Silicones Corporation
    Inventors: Jodi Mecca, James Keenihan, Marc-Andre Courtemanche, Keith Bruce, Igor Chorvath, Sean Gaal
  • Patent number: 12083092
    Abstract: This disclosure provides compounds of Formula (I) as described herein, along with pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds, and methods to use these compounds, salts and compositions for treating viral infections.
    Type: Grant
    Filed: April 20, 2021
    Date of Patent: September 10, 2024
    Assignees: Novartis AG, Katholieke Universiteit Leuven, Korea Research Institute of Chemical Technology
    Inventors: Johan Neyts, Daniel Poon, Keith Bruce Pfister, Young-Sik Jung, Soo Bong Han, Yashwardhan R. Malpani, Prashant Chakrasali, Sang-Ho Lee, Chong-Kyo Lee, Chonsaeng Kim, Jin Soo Shin, Hae Soo Kim
  • Patent number: 12060488
    Abstract: A composition and a method for preparing a polymer composite article. The composition comprises (A) a filler in an amount of from 10 to 90 wt. %. The composition also comprises (B) a polymer in an amount of from 10 to 90 wt. %, wherein the (B) polymer comprises a polyvinyl. Further, the composition comprises (C) an organopolysiloxane in an amount of from greater than 0 to 10 wt. %; the (C) organopolysiloxane having at least one silicon-bonded hydroxyl group and a viscosity of from 1,000 to 60,000 mPa·s at 25° C. The ranges for components (A)-(C) are based on the total weight of components (A), (B) and (C) in the composition.
    Type: Grant
    Filed: February 1, 2019
    Date of Patent: August 13, 2024
    Assignees: DOW SILICONES CORPORATION, DOW GLOBAL TECHNOLOGIES LLC, ROHM AND HAAS COMPANY
    Inventors: Keith Bruce, Igor Chorvath, Marc-Andre Courtemanche, Jon V. Degroot, Jr., Sean Gaal, Craig Gross, Hailan Guo, James Keenihan, Shawn Mealey, Scott Miller, Tom Parsons, Steven R. Rapacki, Andrew Schlader, Cristina Serrat, Lauren Tonge
  • Publication number: 20240124709
    Abstract: A composition and a method for preparing a polymer composite article. The composition comprises (A) a filler in an amount of from 10 to 90 wt. The composition also comprises (B) a polymer in an amount of from 10 to 90 wt. %. wherein the (B) polymer is selected from polyolefins, polyamides, polyesters, or combinations thereof. Further, the composition comprises (C) an organopolysiloxane in an amount of from greater than 0 to 10 wt. %; the (C) organopolysiloxane having at least one silicon-bonded hydroxyl group and a viscosity of from 1,000 to 60,000 mPa·s at 25° C. The ranges for components (A)-(C) arc based on the total weight of components (A), (B) and (C) in the composition.
    Type: Application
    Filed: December 6, 2023
    Publication date: April 18, 2024
    Inventors: Keith BRUCE, Igor CHORVATH, Marc-Andre COURTEMANCHE, Jon V. DEGROOT, JR., Sean GAAL, Craig GROSS, James KEENIHAN, Shawn MEALEY, Scott MILLER, Tom PARSONS, Andrew SCHLADER, Cristina SERRAT, Lauren TONGE
  • Patent number: 11884821
    Abstract: A composition and a method for preparing a polymer composite article. The composition comprises (A) a filler in an amount of from 10 to 90 wt. The composition also comprises (B) a polymer in an amount of from 10 to 90 wt. %, wherein the (B) polymer is selected from polyolefins, polyamides, polyesters, or combinations thereof. Further, the composition comprises (C) an organopolysiloxane in an amount of from greater than 0 to 10 wt. %; the (C) organopolysiloxane having at least one silicon-bonded hydroxyl group and a viscosity of from 1,000 to 60,000 mPa·s at 25° C. The ranges for components (A)-(C) are based on the total weight of components (A), (B) and (C) in the composition.
    Type: Grant
    Filed: November 17, 2021
    Date of Patent: January 30, 2024
    Assignees: Dow Silicones Corporation, Dow Global Technologies LLC
    Inventors: Keith Bruce, Igor Chorvath, Marc-Andre Courtemanche, Jon V. Degroot, Jr., Sean Gaal, Craig Gross, James Keenihan, Shawn Mealey, Scott Miller, Tom Parsons, Andrew Schlader, Cristina Serrat, Lauren Tonge
  • Publication number: 20240026158
    Abstract: A polydiorganosiloxane is useful in a composition and a method for preparing a wood plastic composite article. The wood plastic composite article is useful as a building material. The polydiorganosiloxane may be added to the composition in liquid form or may form part of a solid carrier component used to make the wood plastic composite article.
    Type: Application
    Filed: October 6, 2023
    Publication date: January 25, 2024
    Inventors: Jodi Mecca, James Keenihan, Marc-Andre Courtemanche, Keith Bruce, Igor Chorvath, Sean Gaal
  • Patent number: 11859086
    Abstract: A polydiorganosiloxane is useful in a composition and a method for preparing a wood plastic composite article. The wood plastic composite article is useful as a building material. The polydiorganosiloxane may be added to the composition in liquid form or may form part of a solid carrier component used to make the wood plastic composite article.
    Type: Grant
    Filed: June 10, 2020
    Date of Patent: January 2, 2024
    Assignee: DOW SILICONES CORPORATION
    Inventors: Jodi Mecca, James R. Keenihan, Marc-Andre Courtemanche, Keith Bruce, Igor Chorvath, Sean Gaal
  • Patent number: 11820898
    Abstract: A polydiorganosiloxane is useful in a composition and a method for preparing a wood plastic composite article. The wood plastic composite article is useful as a building material. The polydiorganosiloxane may be added to the composition in liquid form or may form part of a solid carrier component used to make the wood plastic composite article.
    Type: Grant
    Filed: November 4, 2022
    Date of Patent: November 21, 2023
    Assignee: Dow Silicones Corporation
    Inventors: Jodi Mecca, James Keenihan, Marc-Andre Courtemanche, Keith Bruce, Igor Chorvath, Sean Gaal
  • Publication number: 20230102976
    Abstract: A polydiorganosiloxane is useful in a composition and a method for preparing a wood plastic composite article. The wood plastic composite article is useful as a building material. The polydiorganosiloxane may be added to the composition in liquid form or may form part of a solid carrier component used to make the wood plastic composite article.
    Type: Application
    Filed: November 4, 2022
    Publication date: March 30, 2023
    Inventors: Jodi Mecca, James Keenihan, Marc-Andre Courtemanche, Keith Bruce, Igor Chorvath, Sean Gaal
  • Publication number: 20220251389
    Abstract: A polydiorganosiloxane is useful in a composition and a method for preparing a wood plastic composite article. The wood plastic composite article is useful as a building material. The polydiorganosiloxane may be added to the composition in liquid form or may form part of a solid carrier component used to make the wood plastic composite article.
    Type: Application
    Filed: June 10, 2020
    Publication date: August 11, 2022
    Inventors: Jodi Mecca, James R. Keenihan, Marc-Andre Courtemanche, Keith Bruce, Igor Chorvath, Sean Gaal
  • Patent number: 11377561
    Abstract: An alkenyl-functional polydiorganosiloxane is useful in a composition and a method for preparing a wood plastic composite article. The wood plastic composite article is useful as a building material. The polydiorganosiloxane may be added in liquid form to a composition, or may form part of a solid carrier component, used to make the wood plastic composite article.
    Type: Grant
    Filed: June 10, 2020
    Date of Patent: July 5, 2022
    Assignee: Dow Silicones Corporation
    Inventors: Igor Chorvath, Marc-Andre Courtemanche, James Keenihan, Keith Bruce, Sean Gaal, Jodi Mecca
  • Patent number: 11312862
    Abstract: A solid carrier component includes a liquid polydiorganosiloxane and an ethylene-based polymer. The solid carrier component is useful in processes for preparing wood plastic composite articles, such as building materials.
    Type: Grant
    Filed: June 10, 2020
    Date of Patent: April 26, 2022
    Assignee: Dow Silicones Corporation
    Inventors: James Keenihan, Marc-Andre Courtemanche, Igor Chorvath, Keith Bruce, Jodi Mecca
  • Patent number: 11312861
    Abstract: A solid carrier component includes a liquid polydiorganosiloxane, an ethylene-based polymer, and a maleated ethylene-based polymer. The solid carrier component is useful in processes for preparing filled composite articles, such as wood plastic composite building materials.
    Type: Grant
    Filed: June 10, 2020
    Date of Patent: April 26, 2022
    Assignee: Dow Silicones Corporation
    Inventors: Marc-Andre Courtemanche, James R. Keenihan, Igor Chorvath, Keith Bruce, Jodi M. Mecca
  • Publication number: 20220105091
    Abstract: The invention provides compounds of Formula (I) as described herein, along with pharmaceutically acceptable salts, pharmaceutical compositions and pharmaceutical combinations containing such compounds, as well as methods to use these compounds, salts and compositions for treating viral infections, particularly infections caused by hepatitis B virus (HBV), and for reducing the occurrence of serious conditions associated with HBV.
    Type: Application
    Filed: December 14, 2021
    Publication date: April 7, 2022
    Inventors: Jiping Fu, Wooseok Han, Xianming Jin, Keith Bruce Pfister, Joseph Michael Young
  • Publication number: 20220073748
    Abstract: A composition and a method for preparing a polymer composite article. The composition comprises (A) a filler in an amount of from 10 to 90 wt. The composition also comprises (B) a polymer in an amount of from 10 to 90 wt. %, wherein the (B) polymer is selected from polyolefins, polyamides, polyesters, or combinations thereof. Further, the composition comprises (C) an organopolysiloxane in an amount of from greater than 0 to 10 wt. %; the (C) organopolysiloxane having at least one silicon-bonded hydroxyl group and a viscosity of from 1,000 to 60,000 mPa·s at 25° C. The ranges for components (A)-(C) are based on the total weight of components (A), (B) and (C) in the composition.
    Type: Application
    Filed: November 17, 2021
    Publication date: March 10, 2022
    Inventors: Keith BRUCE, Igor CHORVATH, Marc-Andre COURTEMANCHE, Jon V. DEGROOT, JR., Sean GAAL, Craig GROSS, James KEENIHAN, Shawn MEALEY, Scott MILLER, Tom PARSONS, Andrew SCHLADER, Cristina SERRAT, Lauren TONGE
  • Publication number: 20220041864
    Abstract: A solid carrier component includes a liquid polydiorganosiloxane and an ethylene-based polymer. The solid carrier component is useful in processes for preparing wood plastic composite articles, such as building materials.
    Type: Application
    Filed: June 10, 2020
    Publication date: February 10, 2022
    Inventors: James Keenihan, Marc-Andre Courtemanche, Igor Chorvath, Keith Bruce, Jodi Mecca