Patents by Inventor Keith Clinch

Keith Clinch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing kifunensine intermediate and kifunensine therefrom
    Publication number: 20040063973
    Abstract: A novel method for the preparation of a compound of formula (I) from an N-protected-D-mannosamine. A compound of formula (I) is a useful intermediate for the preparation of kiftnensine, a potent and selective mannosidase inhibitor.
    Type: Application
    Filed: July 8, 2003
    Publication date: April 1, 2004
    Applicant: Industrial Research Limited
    Inventors: Paul Andrew Benjes, Ashley Nicholas Jarvis, Gary Brian Evans, Gavin Frank Painter, John Adrian Dickison, Anthony Mitchell, Keith Clinch
  • Enzyme detection/assay method and substrates
    Publication number: 20020132263
    Abstract: The invention relates to a method of detecting and/or assaying nucleoside hydrolases or nucleoside phosphorylases using a chromogenic substrate. Preferred chromogenic substrates have formula (I) where X is OH, or H, and Y is the residue of Y—OH where Y—OH is a chromophore or a compound readily converted to a chromophore and the substrates are hydrolysed by the nucleoside hydrolase to yield ribose or 2-deoxyribose plus Y—OH. Alternatively those substrates may be phosphorylysed by nucleoside phosphorylase to yield ribose-1-phosphate plus Y—OH. The methods may be used to detect and/or assay parasites in biological samples.
    Type: Application
    Filed: March 18, 2002
    Publication date: September 19, 2002
    Inventors: Vern L. Schramm, Richard Hubert Furneaux, Peter Charles Tyler, Keith Clinch
  • Enzyme detection/assay method and substrates
    Patent number: 6379911
    Abstract: The invention relates to a method of detecting and/or assaying nucleoside hydrolases or nucleoside phosphorylases using a chromogenic substrate. Preferred chromogenic substrates have formula (I) where X is OH, or H, and Y is the residue of Y—OH where Y—OH is a chromophore or a compound readily converted to a chromophore and the substrates are hydrolyzed by the nucleoside hydrolase to yield ribose or 2-deoxyribose plus Y—OH. Alternatively, those substrates may be phosphorylysed by nucleoside phosphorylase to yield ribose-1-phosphate plus Y—OH. The methods may be used to detect and/or assay parasites in biological samples.
    Type: Grant
    Filed: February 22, 1999
    Date of Patent: April 30, 2002
    Assignees: Albert Einstein College of Medicine of Yeshiva University, Industrial Research Limited
    Inventors: Vern L. Schramm, Richard Hubert Furneaux, Peter Charles Tyler, Keith Clinch
  • ENZYME DETECTION/ASSAY METHOD AND SUBSTRATES
    Publication number: 20010019823
    Abstract: The invention relates to a method of detecting and/or assaying nucleoside hydrolases or nucleoside phosphorylases using a chromogenic substrate. Preferred chromogenic substrates have formula (I) where X is OH, or H, and Y is the residue of Y—OH where Y—OH is a chromophore or a compound readily converted to a chromophore and the substrates are hydrolysed by the nucleoside hydrolase to yield ribose or 2-deoxyribose plus Y—OH. Alternatively those substrates may be phosphorylysed by nucleoside phosphorylase to yield ribose-1-phosphate plus Y—OH. The methods may be used to detect and/or assay parasites in biological samples.
    Type: Application
    Filed: February 22, 1999
    Publication date: September 6, 2001
    Inventors: VERN L. SCHRAMM, RICHARD HUBERT FURNEAUX, PETER CHARLES TYLER, KEITH CLINCH