Patents by Inventor Keith Crawford

Keith Crawford has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240019435
    Abstract: The present invention provides biological molecules for use in detecting, identifying and/or removing microbes and microbial components; diagnostic, therapeutic and filtration devices comprising the biological molecules; and systems and methods for treating fluids using the biological molecules and devices of the invention.
    Type: Application
    Filed: September 24, 2021
    Publication date: January 18, 2024
    Applicant: MIRAKI INNOVATION THINK TANK LLC
    Inventors: Nisha Veronica VARMA, Keith CRAWFORD, Gregory T. MARTIN, Goossen Jan Bernard BOER, Rainuka GUPTA, Zhiqian ZHOU, Christopher VELIS, Andrew D. CONNERTY
  • Publication number: 20240011980
    Abstract: Detection devices comprising microbe-targeting molecules (MTMs) and engineered MTMs in the form of a lateral flow assay (LFA) are provided. Methods of using the detection devices in the detection and/or identification of microbes and microbe components in a sample are also provided.
    Type: Application
    Filed: June 11, 2021
    Publication date: January 11, 2024
    Applicant: MIRAKI INNOVATION THINK TANK LLC
    Inventors: Nisha Veronica VARMA, Goossen Jan Bernard BOER, Zhiqian ZHOU, George A. DOWNEY, Shailendra KUMAR, Keith CRAWFORD
  • Publication number: 20240001019
    Abstract: The present invention provides mannose-binding lectin (MBL)-based compositions, and methods of using the MBL-based compositions in the reduction of unintended platelet activation, such as during a medical procedure.
    Type: Application
    Filed: July 30, 2021
    Publication date: January 4, 2024
    Applicant: MIRAKI INNOVATION THINK TANK LLC
    Inventors: Nisha Veronica VARMA, Zhiqian ZHOU, Keith CRAWFORD, Andrew D. CONNERTY, Shailendra KUMAR
  • Publication number: 20230416319
    Abstract: Compositions, devices and methods for capturing, detecting and identifying one or more microbes or microbe components and/or treating infectious disease using microbe-targeting molecules (MTMs) are provided.
    Type: Application
    Filed: September 30, 2021
    Publication date: December 28, 2023
    Applicant: MIRAKI INNOVATION THINK TANK LLC
    Inventors: Keith CRAWFORD, Christopher VELIS, Goossen Jan Bernard BOER, George A. DOWNEY
  • Publication number: 20230270927
    Abstract: The present invention provides biological molecules for use in detecting, identifying and/or removing microbes and microbial components; diagnostic, therapeutic and filtration devices comprising the biological molecules; and systems and methods for treating fluids using the biological molecules and devices of the invention.
    Type: Application
    Filed: December 23, 2020
    Publication date: August 31, 2023
    Applicant: Miraki Innovation Think Tank LLC
    Inventors: Nisha Veronica VARMA, Keith CRAWFORD, Gregory T. MARTIN, Goossen Jan Bernard BOER, Rainuka GUPTA, Zhiqian ZHOU, Christopher VELIS, Andrew D. CONNERTY
  • Patent number: 8877198
    Abstract: It is disclosed here a method for reducing phosphate absorption in a human or non-human animal subject wherein the subject consumes a diet containing phytic acid or phytate and either has or is at risk of developing hyperphosphatemia. The method includes the step of administering orally to the subject an anti-intestinal alkaline phosphatase antibody in an amount effective to reduce or maintain the serum phosphate concentration in the subject.
    Type: Grant
    Filed: October 23, 2007
    Date of Patent: November 4, 2014
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Mark Cook, Martin Petkovich, Christian Helvig, Erica Hellestad, Keith Crawford
  • Patent number: 8802094
    Abstract: A method for reducing phosphate absorption in a human or non-human animal subject at risk of developing or having developed hyperphosphatemia is disclosed. The method includes the step of administering orally to the subject an anti-intestinal sodium phosphate cotransporter type 2B (Npt2B) antibody in an amount effective to reduce or maintain the serum phosphate concentration in the subject.
    Type: Grant
    Filed: October 23, 2007
    Date of Patent: August 12, 2014
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Mark Cook, Martin Petkovich, Christian Helvig, Erica Hellestad, Keith Crawford
  • Publication number: 20100233184
    Abstract: It is disclosed here a method for reducing phosphate absorption in a human or non-human animal subject wherein the subject consumes a diet containing phytic acid or phytate and either has or is at risk of developing hyperphosphatemia. The method includes the step of administering orally to the subject an anti-intestinal alkaline phosphatase antibody in an amount effective to reduce or maintain the serum phosphate concentration in the subject.
    Type: Application
    Filed: October 23, 2007
    Publication date: September 16, 2010
    Applicants: WISCONSIN ALUMI RESEARCH FOUNDATION, AOVATECHNOLOGIES, INC.
    Inventors: Mark Cook, Martin Petkovich, Christian Helvig, Erica Hellestad, Keith Crawford
  • Publication number: 20100166760
    Abstract: A method for reducing phosphate absorption in a human or non-human animal subject at risk of developing or having developed hyperphosphatemia is disclosed. The method includes the step of administering orally to the subject an anti-intestinal sodium phosphate cotransporter type 2B (Npt2B) antibody in an amount effective to reduce or maintain the serum phosphate concentration in the subject.
    Type: Application
    Filed: October 23, 2007
    Publication date: July 1, 2010
    Inventors: Mark Cook, Martin Petkovich, Christian Helvig, Erica Hellestad, Keith Crawford
  • Patent number: 7633059
    Abstract: A tandem mass spectrometer and method for calibrating a tandem mass spectrometer. The tandem mass spectrometer comprises first and second mass analyzers. The first and second mass analyzers form an ion path. The second mass analyzer is positioned downstream from the first mass analyzer and is arranged to receive ions from the first mass analyzer. An electrode arrangement positioned between the first and second mass analyzers. The electrode assembly is configured to selectively deflect ions from the ion path.
    Type: Grant
    Filed: October 13, 2006
    Date of Patent: December 15, 2009
    Assignee: Agilent Technologies, Inc.
    Inventors: Charles William Russ, IV, Robert Keith Crawford, Steven Michael Fischer
  • Patent number: 7421851
    Abstract: An application and method for disinfecting HVAC systems that includes features for protecting service personnel from unintended exposure to ultraviolet radiation. The safeguards include an interlock that prevents illumination of germicidal lamps when their enclosure case is not properly attached to a duct.
    Type: Grant
    Filed: July 12, 2006
    Date of Patent: September 9, 2008
    Assignee: UltraViolet Devices, Inc.
    Inventors: David L. Witham, Thomas M. Veloz, Thomas C. Bowles, Roberto Arance, Keith Crawford, Jon W. Orr, Richard N. Metzger, Larry F. Randall
  • Publication number: 20080087809
    Abstract: A tandem mass spectrometer and method for calibrating a tandem mass spectrometer. The tandem mass spectrometer comprises first and second mass analyzers. The first and second mass analyzers form an ion path. The second mass analyzer is positioned downstream from the first mass analyzer and is arranged to receive ions from the first mass analyzer. An electrode arrangement positioned between the first and second mass analyzers. The electrode assembly is configured to selectively deflect ions from the ion path.
    Type: Application
    Filed: October 13, 2006
    Publication date: April 17, 2008
    Inventors: Charles William Russ, Robert Keith Crawford, Steven Michael Fischer
  • Publication number: 20070122477
    Abstract: A controlled-release pharmaceutical formulation including cholecalciferol and/or ergocalciferol, a method of making the formulation, and a method of administering the formulation to treat 25-hydroxyvitamin D insufficiency or deficiency, are disclosed. The composition and method of administration preferably result in delayed release of the vitamin(s) in the ileum of the small intestine and sustained, substantially constant, release of the vitamin(s) over an extended period, e.g., at least 4 hours or more. Individual and combined dosages of 500 IU to 50,000 IU per dosage form, preferably daily, are disclosed.
    Type: Application
    Filed: October 12, 2006
    Publication date: May 31, 2007
    Applicant: CYTOCHROMA, INC.
    Inventors: Charles Bishop, Keith Crawford, Eric Messner
  • Publication number: 20070058367
    Abstract: A system and a method for keying lamps which involve a lamp keying device such as a keying device with at least one base protruding key being formed on the base and at least one support slot being formed in the lamp support receptacle, the at least one base protruding key detachably coupling with the at least one support slot; a keying device with at least one support protruding key being formed on the lamp support receptacle and at least one base slot being formed in the base, the at least one base slot detachably coupling with the at least one protruding support key; and a keying device with at least one base protruding key being formed on the base and at least one base slot being formed in the base, the keying device further having at least one complementary support protruding key being formed on the lamp support receptacle and at least one complementary support slot being formed in the lamp support receptacle, the at least one base protruding key detachably coupling with the at least one complementary sup
    Type: Application
    Filed: November 16, 2006
    Publication date: March 15, 2007
    Inventors: David Witham, Roberto Arance, Keith Crawford, Michael Pedersen, Michael Jacques
  • Publication number: 20060270700
    Abstract: The present invention relates to the use of sigma-2 agonists to potentiate the activity of antineoplastic agents. These substances are useful for treating cancerous tumors and, in particular, drug resistant tumors in humans. Methods for sensitizing multidrug resistant cells to antitumor agents comprising contact the cells with a sigma-2 agonist are also described.
    Type: Application
    Filed: August 1, 2006
    Publication date: November 30, 2006
    Inventors: Keith Crawford, Wayne Bowen
  • Publication number: 20060254298
    Abstract: An application and method for disinfecting HVAC systems that includes features for protecting service personnel from unintended exposure to ultraviolet radiation. The safeguards include an interlock that prevents illumination of germicidal lamps when their enclosure case is not properly attached to a duct.
    Type: Application
    Filed: July 12, 2006
    Publication date: November 16, 2006
    Inventors: David Witham, Thomas Veloz, Thomas Bowles, Roberto Arance, Keith Crawford, Jon Orr, Richard Metzger, Larry California
  • Patent number: 7107778
    Abstract: A device (20) for Disinfection of HVAC Systems that include features that will protect service personnel from un-intended exposure to ultra violet radiation. The safeguards include an interlock (70) that prevents illumination of germicidal lamps (80) when an enclosure within which the germicidal lamps (80) are mounted is not properly attached to a duct or appliance; the apparatus further provides for innovative methods for determining that the germicidal lamps (80) are operating.
    Type: Grant
    Filed: September 15, 2000
    Date of Patent: September 19, 2006
    Inventors: David L. Witham, Thomas M. Veloz, Thomas C. Bowles, Roberto Arance, Keith Crawford, Jon W. Orr, Richard N. Metzger, Larry F. Randall
  • Publication number: 20060004036
    Abstract: The present invention relates to sigma-2 receptor agonists and their use in the treatment of immunodeficiency virus infections, especially human immunodeficiency virus (HIV) infections. The invention particularly relates to sigma-2 agonists, especially CB-184 and its analogues, that decrease cellular production of sphingomyelin when provided to recipient cells, and inhibit HIV replication.
    Type: Application
    Filed: July 15, 2005
    Publication date: January 5, 2006
    Applicant: The United States of America, per Secy. DHHS, NIH
    Inventors: Wayne Bowen, Keith Crawford, James Hildreth
  • Publication number: 20050239756
    Abstract: The present invention provides a method of increasing or maintaining blood concentrations of 1,25-dihydroxyvitamin D in a patient by administering an amount of 1?-hydroxyvitamin D2. The invention also provides a method of concurrently lowering or maintaining plasma intact parathyroid hormone levels, increasing or maintaining serum calcium levels, maintaining serum phosphorous levels, or increasing or maintaining serum 1,25-dihydroxyvitamin D levels in a human patient by administering to the patient an amount of 1?-hydroxyvitamin D2. The invention also provides a method of reducing the risk of over suppression of plasma intact parathyroid hormone levels in a patient undergoing treatment for elevated levels of plasma intact parathyroid hormone, by administering 1?-hydroxyvitamin D2 in an amount sufficient to decrease elevated intact parathyroid hormone levels while avoiding an abnormally low bone turnover rate.
    Type: Application
    Filed: April 25, 2005
    Publication date: October 27, 2005
    Applicant: Bone Care International, Inc.
    Inventors: Charles Bishop, Eric Messner, Keith Crawford
  • Publication number: 20050163650
    Abstract: The present invention is a neutralization system for particulates including germs, organisms, and airborne pathogens. The invention includes a duct, a lamp with at least one ultraviolet tube therein, an optically transmissible element, and a light panel. The duct has an exterior surface with openings and an interior volume through which an air stream is directed. The lamp is fastened to the exterior surface of the duct over a first opening. The optically transmissible element is secured between lamp and duct so as to prevent the air stream from contacting the ultraviolet tubes within the lamp. The light panel is comprised of a frame about a porous mat composed of a plurality of end emitting optical fibers. The panel is slidably disposed through a second opening so as to bisect the air stream. A first end of each end emitting optical fiber is positioned so as to allow ultraviolet light from the lamp to enter the fiber.
    Type: Application
    Filed: January 22, 2004
    Publication date: July 28, 2005
    Inventors: Keith Crawford, Timothy Mitchell