Patents by Inventor KEITH DRENGLER

KEITH DRENGLER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of iopamidol
    Patent number: 7282607
    Abstract: The present invention discloses a process for the preparation of pure non-ionic contrast agents. The invention also includes a method for purifying the non-ionic contrast agents.
    Type: Grant
    Filed: August 16, 2006
    Date of Patent: October 16, 2007
    Assignee: Bracco Imaging, S.p.A.
    Inventors: Richard A. Lorenzini, Ashok V. Bhatia, Steven A. Chamberlin, Keith A. Drengler, John J. Hufnagel, Xiu C. Wang
  • Process for the Preparation of Iopamidol
    Publication number: 20070078281
    Abstract: The present invention discloses a process for the preparation of pure non-ionic contrast agents. The invention also includes a method for purifying the non-ionic contrast agents.
    Type: Application
    Filed: August 16, 2006
    Publication date: April 5, 2007
    Applicant: BRACCO IMAGING S.P.A.
    Inventors: Richard Lorenzini, Ashok Bhatia, Steven Chamberlin, Keith Drengler, John Hufnagel, Xiu Wang
  • Process for the preparation of iopamidol
    Patent number: 7115778
    Abstract: The present invention discloses a process for the preparation of pure non-ionic contrast agents. The invention also includes a method for purifying the non-ionic contrast agents.
    Type: Grant
    Filed: February 24, 2005
    Date of Patent: October 3, 2006
    Assignee: Bracco imaging, S.p.A.
    Inventors: Richard A. Lorenzini, Ashok V. Bhatia, Steven A. Chamberlin, Keith A. Drengler, John J. Hufnagel, Xiu C. Wang
  • Process for the preparation of iopamidol
    Publication number: 20050192465
    Abstract: The present invention discloses a process for the preparation of pure non-ionic contrast agents. The invention also includes a method for purifying the non-ionic contrast agents.
    Type: Application
    Filed: February 24, 2005
    Publication date: September 1, 2005
    Applicant: Bracco Imaging S.p.A.
    Inventors: Richard Lorenzini, Ashok Bhatia, Steven Chamberlin, Keith Drengler, John Hufnagel, Xiu Wang
  • Process for the preparation of iopamidol
    Patent number: 6875887
    Abstract: A compound and salts and enantiomers thereof, having the formula: wherein R7 is an acyl group.
    Type: Grant
    Filed: June 16, 2004
    Date of Patent: April 5, 2005
    Assignee: Bracco Imaging S.p.A.
    Inventors: Richard A. Lorenzini, Ashok V. Bhatia, Steven A. Chamberlin, Keith A. Drengler, John J. Hufnagel, Xiu C. Wang
  • Process for the preparation of iopamidol
    Publication number: 20040236150
    Abstract: The present invention discloses a process for the preparation of pure non-ionic contrast agents. The invention also includes a method for purifying the non-ionic contrast agents.
    Type: Application
    Filed: June 16, 2004
    Publication date: November 25, 2004
    Inventors: Richard A. Lorenzini, Ashok V. Bhatia, Steven A. Chamberlin, Keith A. Drengler, John J. Hufnagel, Xiu C. Wang
  • Process for the preparation of iopamidol
    Patent number: 6803485
    Abstract: The present invention discloses a process for the preparation of pure non-ionic contrast agents. The invention also includes a method for purifying the non-ionic contrast agents.
    Type: Grant
    Filed: February 26, 1999
    Date of Patent: October 12, 2004
    Assignee: Bracco Imaging S.p.A.
    Inventors: Richard A. Lorenzini, Ashok V. Bhatia, Steven A. Chamberlin, Keith A. Drengler, John J. Hufnagel, Xiu C. Wang
  • PROCESS FOR THE PREPARATION OF IOPAMIDOL
    Publication number: 20010056206
    Abstract: The present invention discloses a process for the preparation of pure non-ionic contrast agents. The invention also includes a method for purifying the non-ionic contrast agents.
    Type: Application
    Filed: February 26, 1999
    Publication date: December 27, 2001
    Inventors: RICHARD LORENZINI, ASHOK BHATIA, STEVE CHAMBERLIN, KEITH DRENGLER, JOHN HUFNAGEL, XIU WANG
  • Process for the preparation and isolation of atracurium besylate
    Patent number: 5684154
    Abstract: A process of producing atracurium besylate that substantially reduces the level of impurities in the final product and avoids the repeated use of ether is provided. In accordance with such a process, N, N'-4,10-dioxa-3,11-dioxotridecylene-1,13-bis-tetrahydropapaverine (Compound 1), methyl benzenesulfonate and a catalytic amount of an insoluble base in a solvent are combined to form a reaction mixture that is maintained for a period of time sufficient for atracurium besylate formation. The reaction mixture is then filtered to remove the insoluble base and the atracuriurn besylate is precipitated.
    Type: Grant
    Filed: February 16, 1996
    Date of Patent: November 4, 1997
    Assignee: Abbott Laboratories
    Inventors: Steven A. Chamberlin, Ashok V. Bhatia, Deborah A. Davis, Keith A. Drengler
  • Resorcyclic acid lactone derivatives as animal growth promotants
    Patent number: 5041610
    Abstract: Ring-opened resorcyclic acid lactone derivatives of the formla ##STR1## wherein X is ethylene or ethenylene; Y and Z, which may be the same or different, are methylene, hydroxymethylene or carbonyl; R.sub.1 is hydrogen or lower alkyl of from 1 to about 6 carbon atoms; R.sub.2, R.sub.3, R.sub.4 and R.sub.5, which may be the same or different, are hydrogen, hydroxyl, halogen, nitro, amino or a radical selected from the group consisting of --R', --OR', --COOR' and --OCOR' wherein R' is lower alkyl of from 1 to about 6 carbon atoms, lower cycloalkyl of from 3 to about 8 carbon atom, alkenyl of from 2 to about 6 carbon atoms, substituted or unsubstituted aryl of from 6 to about 8 carbon atoms, or substituted or unsubstituted aralkyl wherein the alkyl portion contains from 1 to about 6 carbon atoms and the aryl portion contains from 6 to about 8 carbon atoms. These compounds are useful as growth-promotants in food-producing animals.
    Type: Grant
    Filed: November 28, 1986
    Date of Patent: August 20, 1991
    Assignee: International Minerals & Chemical Corp.
    Inventor: Keith A. Drengler
  • Growth hormone-releasing factor analogs
    Patent number: 4801456
    Abstract: Human Growth Hormone-Releasing Factor (hGRF) analogs having the sequence [X.sup.3, Y.sup.8, Z.sup.25, Nle.sup.27 ]-hGRF(1-A)--B, wherein X, Y, and Z are selected from the group consisting of Asn and Asp, A has a value from 29-44, and B is NH.sub.2 or OH are synthesized and administered to animals to stimulate the release of Growth Hormone (GH).
    Type: Grant
    Filed: July 9, 1987
    Date of Patent: January 31, 1989
    Assignee: International Minerals & Chemical Corp.
    Inventor: Keith A. Drengler
  • Growth hormone-releasing factor analogs
    Patent number: RE33699
    Abstract: Human Growth Hormone-Releasing Factor (hGRF) analogs having the sequence [X.sup.3, Y.sup.8, Z.sup.25, Nle.sup.27 ]-hGRF(1-A)--B, wherein X, Y and Z are selected from the group consisting of Asn and Asp, A has a value from 29-44, and B is NH.sub.2 or OH are synthesized and administered to animals to stimulate the release of Growth Hormone (GH).
    Type: Grant
    Filed: May 21, 1990
    Date of Patent: September 24, 1991
    Assignee: International Minerals & Chemical Corp.
    Inventor: Keith A. Drengler