Patents by Inventor Keith E. Garrison

Keith E. Garrison has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human Endogenous Retrovirus Polypeptide Compositions and Methods of Use Thereof
    Publication number: 20130323279
    Abstract: The present invention provides isolated HERV polypeptides; and compositions, including immunogenic compositions, comprising a HERV polypeptide. The present invention provides immunogenic compositions comprising a nucleic acid comprising a nucleotide sequence encoding a HERV polypeptide. The immunogenic compositions are useful for stimulating a T cell immune response to a lentiviral peptide. The present invention further provides methods of stimulating an immune response in an individual to a retrovirus- or lentivirus-infected cell. The present invention further provides methods of treating cancers in which HERV polypeptides are expressed. Also provided are methods of treating disorders, involving decreasing an immune response to a HERV polypeptide.
    Type: Application
    Filed: May 10, 2013
    Publication date: December 5, 2013
    Applicants: The J. David Gladstone Institutes, Albert Einstein College of Medicine of Yeshiva University, The Regents of the University of California, The Governing Counicl of University of Toronto
    Inventors: Douglas F. Nixon, Keith E. Garrison, Duncan A. Meiklejohn, Mario A. Ostrowski, R. Bradley Jones, Ashish Agrawal, Jack Lenz, Seth Rakoff-Nahoum, Frederick M. Hecht