Abstract: A biodegradable nasal splint comprising a tubular component at least partially defining a hollow passageway. The tubular component may be formed from a degradable material comprising a copolymer comprising glycolide subunits, trimethyl carbonate subunits, and caprolactone subunits. The degradable material may further comprise from about 0.01% to about 30% chitosan, by weight of the degradable material. The biodegradable nasal splint may further comprise a therapeutic agent such as chitosan applied to one or more surfaces of the nasal splint Also, a biodegradable nasal splint comprising a tubular component at least partially defining a hollow passageway and formed from a degradable material. The degradable material may comprise at least about 95% chitosan, by weight of the degradable material.

Abstract: A method of providing therapy to a tissue site. The method may include collecting three-dimensional (3-D) data associated with the tissue site, selecting at least one parameter of a customized tissue support based upon the 3-D data, and fabricating the customized tissue support including the design parameter. The method may further include collecting microbiome data associated with the tissue site. Collecting microbiome data may include collecting a biological sample. Collecting microbiome data may further include amplifying genetic material from the biological sample. Collecting the microbiome data may further include evaluating the genetic material from the biological sample. In some embodiments, the method may further include selecting at least one parameter of a customized splint based upon the microbiome data.

Abstract: A biodegradable nasal splint, wherein the biodegradable nasal splint is configured for placement within a nasal passage so as to stabilize a surgically-corrected septum. A biodegradable nasal splint, wherein the biodegradable nasal splint is configured for placement within a nasal passage so as to exert a lateralizing force to an outfractured inferior turbinate. A method comprising performing a corrective procedure with respect to a patient's nasal passage, positioning a biodegradable nasal splint within the patient's nasal passage, wherein the biodegradable nasal splint is effective to exert a lateralizing force to an inferior turbinate, to stabilize a nasal septum, or combinations thereof.