Abstract: A spinal implant includes a first member having an arcuate portion and a second member having an arcuate portion. The first member is connected with a first portion of vertebrae and the second member is connected with a second portion of vertebrae such that the second portion of vertebrae is disposed at a first angle relative to the first portion of vertebrae in a sagittal plane of the vertebrae. A ratchet is disposed with the members such that the first member is incrementally movable relative to the second member from the first angle to a selected angle of the second portion relative to the first portion in the sagittal plane. Systems, implants and methods are disclosed.

Abstract: Per- and polyfluoroalkyl substances (PFAS) are destroyed by oxidation in supercritical conditions. PFAS in water can be concentrated and prepared for destruction in a pretreatment phase. Following annihilation of the PFAS in supercritical conditions to levels below 5 parts per trillion (ppt), the water effluent can be used to recover heat, returned to sub-critical conditions, and then released back into the environment.

Abstract: A continuous glucose monitoring system may utilize externally sourced information regarding the physiological state and ambient environment of its user for externally calibrating sensor glucose measurements. Externally sourced factory calibration information may be utilized, where the information is generated by comparing metrics obtained from the data used to generate the sensor's glucose sensing algorithm to similar data obtained from each batch of sensors to be used with the algorithm in the future. The output sensor glucose value of a glucose sensor may also be estimated by analytically optimizing input sensor signals to accurately correct for changes in sensitivity, run-in time, glucose current dips, and other variable sensor wear effects.

Abstract: A bone screw comprises a shaft defining a longitudinal axis and a minor diameter. The shaft including a core having an angled surface relative to the axis. The angled surface extending from the minor diameter adjacent a proximal portion of the shaft to a distal portion of the shaft, and a wall disposed about the angled surface. The wall including at least one thread having an external thread form. In some embodiments, systems, spinal constructs, surgical instruments and methods are disclosed.

Abstract: Interbody implants may be formed by a product by process in which a first metallic frame component having an interconnected superior endplate and an interconnected inferior endplate are formed. In some embodiments, the endplates are interconnected by flexible struts and in others they are interconnected by translating struts. In various embodiments, a polymeric body may be infilled between the superior endplate and inferior endplate by a molding process, e.g., an injection molding process or an overmolding process. In various embodiments, the metallic frame may have a first compressive stiffness, the polymeric body may have a second compressive stiffness, and the first compressive stiffness of the metallic frame may be about 20% to about 80% of the second stiffness of the body. In various embodiments, a sum of the first compressive stiffness of the metallic frame and the second stiffness of the body is about 33,500 N/mm to about 11,500 N/mm.

Abstract: An expandable spinal implant includes a distal projection extending from only one side of the implant, ending in an anterior tip, the anterior portion and anterior tip defining an elongated distal end hook, which is wider than the proximal end. The distal end hook rotates around the spinal cord, aligning the implant with a desired pathway, then inserts into place in the disc space between the vertebrae. The elongated widened distal end hook provides a TLIF approach, distributes loads, provides anterior rim engagement, and creates lordosis.

Abstract: A bone screw comprises a shaft defining a longitudinal axis and a minor diameter. The shaft including a core having an angled surface relative to the axis. The angled surface extending from the minor diameter adjacent a proximal portion of the shaft to a distal portion of the shaft, and a wall disposed about the angled surface. The wall including at least one thread having an external thread form. In some embodiments, systems, spinal constructs, surgical instruments and methods are disclosed.

Abstract: A surgical table includes a sagittal adjustment device for manipulating the position of a patient. The surgical table includes a base portion including an upper surface for spacing the sagittal adjustment device from the ground. The sagittal adjustment device includes a first support portion and a second support portion. The first and second support portions are supported by and moveable over the upper surface of the base portion. The first and second support portions each include an upper surface configured to support portions of the body of the patient thereon. One of the first and second support portions is pivotally attached to the base portion, and moveable between a first position and a second position. The pivotal movement between the first and second positions of the one of the first and second portions serves in repositioning the body of patient to manipulate the spine of the patient.

Abstract: An expandable spinal implant is provided having first and second endplates hinged along one end and an expansion mechanism disposed therebetween configured to expand the first and second endplates from each other to provide a lordotic angle of up to 60 degrees. Various implants, systems and methods are disclosed.

Abstract: An expandable spinal implant is provided having first and second endplates hinged along one end and an expansion mechanism disposed therebetween configured to expand the first and second endplates from each other to provide a lordotic angle of up to 60 degrees. Various implants, systems and methods are disclosed.

Abstract: An expandable spinal implant is provided having first and second endplates hinged along one end or otherwise connected by pins, protrusions and channels, or similar mechanisms and an expansion mechanism(s) disposed therebetween configured to expand the first and second endplates from each other. Also provided are expandable spinal implants that may be expanded in a parallel manner to increase the height of the device while maintaining a lordotic angle. Other spinal implants may provide dual expansion whereby both height and lordotic angle are adjusted. Various implants, systems and methods are disclosed.

Abstract: An expandable spinal implant includes a distal projection extending from only one side of the implant, ending in an anterior tip, the anterior portion and anterior tip defining an elongated distal end hook, which is wider than the proximal end. The distal end hook rotates around the spinal cord, aligning the implant with a desired pathway, then inserts into place in the disc space between the vertebrae. The elongated widened distal end hook provides a TLIF approach, distributes loads, provides anterior rim engagement, and creates lordosis.

Abstract: An electrical connector assembly having a housing with terminal receiving passages. The terminal receiving passages have wire receiving portions. Wires are positioned in the wire receiving portions. The wires have cable jackets and center conductors. Electrically conductive components for controlling impedance of sections of the wires are positioned in the wire receiving portions of the terminal receiving passages. The electrically conductive components includes base walls with end walls, The end walls extend in a direction which is essentially perpendicular to planes of the base walls. The base walls have lengths which are approximately equal to lengths of the wire receiving portions of the terminal receiving passages. Insulation displacement slots are provided on the end walls. Lead-in sections extend from the insulation displacement slots in a direction away from the base wall.

Abstract: A build-plate with integrally-formed spinal implant constructs and a method used in forming spinal implant constructs on the build-plate and machining the spinal implant constructs formed on the build-plate to manufacture spinal implants is provided. The spinal implant constructs can be formed via additive manufacturing processes by adding material to an upper surface of the build-plate, and then the spinal implant constructs can be subjected to subtractive manufacturing processes to form the spinal implants.

Abstract: A bone screw comprising a shaft having a wall, the wall including a minor diameter and at least one thread having an external thread form. The thread form including a first portion comprising a crest of the thread form and a second portion extends between a minor diameter of the thread form and the first portion. The first portion having a solid configuration relative to the second portion. In some embodiments, systems, spinal constructs, surgical instruments and methods are disclosed.

Abstract: A spinal fusion implant includes a leading end, an opposite trailing end, an upper portion extending between the leading and trailing ends, a lower portion extending between the leading and trailing ends, and opposed first and second side portions extending between the leading and trailing ends. The upper portion includes at least two rails extending between the leading and trailing ends, the at least two rails including a first rail and a second rail spaced apart from one another, the first rail of the upper portion including a bone-contacting surface being at least partially smoothened. The lower portion includes at least two rails extending between the leading and trailing ends, the at least two rails including a first rail and a second rail spaced apart from one another, the first rail of the lower portion including a bone-contacting surface being at least partially smoothened.

Abstract: A build-plate with integrally-formed spinal implant constructs and a method used in forming spinal implant constructs on the build-plate and machining the spinal implant constructs formed on the build-plate to manufacture spinal implants is provided. The spinal implant constructs can be formed via additive manufacturing processes by adding material to an upper surface of the build-plate, and then the spinal implant constructs can be subjected to subtractive manufacturing processes to form the spinal implants.

Abstract: A device includes a core having proximal and distal ends and defining a first female thread. A drive screw includes first and second ends. The first end includes a first male thread. The second end including a second male thread that engages the first female thread. A first body includes a second female thread that engages the first male thread. A second body is coupled to the drive screw. A first plate is coupled to the core and the first body. The first plate includes a first vertebral engaging surface. A second plate is coupled to the core and includes a second vertebral engaging surface. The drive screw is configured to rotate relative to the core to simultaneously pivot the first plate relative to the core and alter a distance between the first vertebral engaging surface and the second vertebral engaging surface.

Abstract: A bone screw comprising a shaft having a wall, the wall including a minor diameter and at least one thread having an external thread form. The thread form including a first portion comprising a crest of the thread form and a second portion extends between a minor diameter of the thread form and the first portion. The first portion having a solid configuration relative to the second portion. In some embodiments, systems, spinal constructs, surgical instruments and methods are disclosed.

Abstract: A device includes a core defining first and second female threads. A first member includes a first body and a first drive screw coupled to the first body, the first drive screw being configured to engage the first female thread. A second member includes a second body and a second drive screw coupled to the second body, the second drive screw being configured to engage the second female thread. A first plate is coupled to the core and the first body. The first plate includes a first vertebral engaging surface. A second plate is coupled to the core and the second body. The second plate includes a second vertebral engaging surface. The drive screws are configured to independently rotate relative to the core to pivot the first plate relative to the core and to alter a distance between the first vertebral engaging surface and the second vertebral engaging surface.