Patents by Inventor Keith E. Rushlow

Keith E. Rushlow has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Feline Fc epsilon receptor alpha chain proteins and therapeutic uses thereof
    Patent number: 5958880
    Abstract: The present invention relates to feline Fc epsilon receptor alpha chain nucleic acid molecules, proteins encoded by such nucleic acid molecules, antibodies raised against such proteins, and inhibitors of such proteins. The present invention also includes methods to detect IgE using such proteins and antibodies. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies and/or inhibitory compounds as well as the use of such therapeutic compositions to mediate Fc epsilon receptor-mediated biological responses.
    Type: Grant
    Filed: December 19, 1996
    Date of Patent: September 28, 1999
    Assignee: Heska Corporation
    Inventors: Glenn R. Frank, James P. Porter, Keith E. Rushlow, Donald L. Wassom, Eric R. Weber
  • Method to detect IgE
    Patent number: 5945294
    Abstract: The present invention includes a method to detect IgE using a human Fc epsilon receptor (Fc.sub..epsilon. R) to detect IgE antibodies in a biological sample from a cat, a dog, or a horse. The present invention also relates to kits to perform such methods.
    Type: Grant
    Filed: November 26, 1996
    Date of Patent: August 31, 1999
    Assignee: Heska Corporation
    Inventors: Glenn R. Frank, James P. Porter, Keith E. Rushlow, Donald L. Wassom
  • Use of protease inhibitors and protease vaccines to protect animals from flea infestation
    Patent number: 5766609
    Abstract: A method to protect a host animal from flea infestation by treating that animal with a composition that includes a compound that reduces protease activity of fleas feeding from the treated animal, thereby reducing flea burden on the animal and in the environment of the animal. The present invention also relates to compositions including flea protease vaccines, anti-flea protease antibodies and/or protease inhibitors. Also included in the present invention are soluble flea midgut preparations, flea protease proteins, nucleic acid molecules encoding such proteins and antibodies that selectively bind to such proteins. The present invention also includes methods to obtain and use such preparations, proteins, nucleic acid molecules, antibodies and protease inhibitors to protect an animal from flea infestation.
    Type: Grant
    Filed: October 18, 1994
    Date of Patent: June 16, 1998
    Assignee: Heska Corporation
    Inventors: Robert B. Grieve, Keith E. Rushlow, Shirley Wu Hunter, Glenn R. Frank, Andrew Heath, Miles Yamanaka, Ann Arfsten, Beverly Dale
  • Flea protease proteins, nucleic acid molecules, and uses thereof
    Patent number: 5712143
    Abstract: The present invention relates to flea serine protease and aminopeptidase proteins; to flea serine protease and aminopeptidase nucleic acid molecules, including those that encode such proteins; to antibodies raised against such proteins; and to compounds that inhibit flea serine protease and/or aminopeptidase activities. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitors. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies, and/or inhibitors as well as the use of such therapeutic compositions to protect a host animal from flea infestation.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 27, 1998
    Assignee: Heska Corporation
    Inventors: Robert B. Grieve, Keith E. Rushlow, Shirley Wu Hunter, Glenn R. Frank, Gary L. Stiegler