Patents by Inventor Keith Fagnou

Keith Fagnou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel compounds and a novel process for their preparation
    Publication number: 20080300271
    Abstract: The present invention is directed to a procedure for making an enantidimerically enriched compound containing a hydronaphthalene ring structure. The process involves reacting oxabenzonorbornadienes with nuclophiles using rhodium as a catalyst and in the presence of a phosphine ligand. The compounds synthesized may be used in pharmaceutical preparations for the treatment of a variety of diseases and conditions.
    Type: Application
    Filed: July 28, 2008
    Publication date: December 4, 2008
    Inventors: Keith Fagnou, Mark Lautens
  • Compounds and a novel process for their preparation
    Patent number: 7420003
    Abstract: The present invention is directed to a procedure for making an enantiomerically enriched compound containing a hydronaphthalene ring structure. The process involves reacting oxabenzonorbornadienes with nucleophiles using rhodium as a catalyst and in the presence of a phosphine ligand. The compounds synthesized may be used in pharmaceutical preparations for the treatment of a variety of diseases and conditions.
    Type: Grant
    Filed: May 28, 2004
    Date of Patent: September 2, 2008
    Assignee: Astrazeneca AB
    Inventors: Keith Fagnou, Mark Lautens
  • Use of N-oxide compounds in coupling reactions
    Publication number: 20080132698
    Abstract: Metal-catalyzed coupling process comprising reacting a compound of general formula 1 with a compound A-X, to obtain a compound of general formula 2, which may further be converted to a compound of general formula 3
    Type: Application
    Filed: November 30, 2006
    Publication date: June 5, 2008
    Inventors: Keith Fagnou, Jean-Philippe Leclerc, Louis-Charles Campeau, David R. Stuart
  • Novel compounds and a novel process for their preparation
    Publication number: 20050014721
    Abstract: The present invention is directed to a procedure for making an enantiomerically enriched compound containing a hydronaphthalene ring structure. The process involves reacting oxabenzonorbornadienes with nucleophiles using rhodium as a catalyst and in the presence of a phosphine ligand. The compounds synthesized may be used in pharmaceutical preparations for the treatment of a variety of diseases and conditions.
    Type: Application
    Filed: May 28, 2004
    Publication date: January 20, 2005
    Inventors: Keith Fagnou, Mark Lautens
  • Compound and a novel process for their preparation
    Patent number: 6784210
    Abstract: The present invention is directed to a procedure for making an enantiomerically enriched compound containing a hydronaphthalene ring structure. The process involves reacting oxabenzonorbornadienes with nucleophiles using rhodium as a catalyst and in the presence of a phosphine ligand. The compounds synthesized may be used in pharmaceutical preparations for the treatment of a variety of diseases and conditions.
    Type: Grant
    Filed: December 12, 2002
    Date of Patent: August 31, 2004
    Assignee: AstraZeneca AB
    Inventors: Keith Fagnou, Mark Lautens
  • Novel compounds and a novel process for their preparation
    Publication number: 20030144275
    Abstract: The present invention is directed to a procedure for making an enantiomerically enriched compound containing a hydronaphthalene ring structure. The process involves reacting oxabenzonorbornadienes with nucleophiles using rhodium as a catalyst and in the presence of a phosphine ligand. The compounds synthesized may be used in pharmaceutical preparations for the treatment of a variety of diseases and conditions.
    Type: Application
    Filed: December 12, 2002
    Publication date: July 31, 2003
    Applicant: AstraZeneca AB
    Inventors: Keith Fagnou, Mark Lautens
  • Hydronaphtalene compounds, prepared by a rhodium catalyzed ring opening reaction in the presence of phosphine ligand
    Patent number: 6525068
    Abstract: The present invention is directed to a procedure for making an enantiomerically enriched compound containing a hydronaphthalene ring structure. The process involves reacting oxabenzonorbornadienes with nucleophiles using rhodium as a catalyst and in the presence of a phosphine ligand. The compounds synthesized may be used in pharmaceutical preparations for the treatment of a variety of diseases and conditions.
    Type: Grant
    Filed: February 27, 2001
    Date of Patent: February 25, 2003
    Assignee: AstraZeneca AB
    Inventors: Keith Fagnou, Mark Lautens