Patents by Inventor Keith Frank

Keith Frank has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11978961
    Abstract: An antenna array may include a plurality of printed circuit boards (PCBs) oriented in a stacked arrangement, parallel to and spaced apart from one another. Each of the PCBs may include a linear array of antenna elements, which cooperate with the linear arrays of antenna elements on other PCBs to form a two-dimensional array of antenna elements. The PCBs may be supported at one end by a common backplate in a cantilevered manner, with the linear arrays of antenna elements located near the free end of the PCBs. The PCBs may include a thicker portion and a thinner portion, and the thinner portion may include a heat sink or other thermal dissipation structure.
    Type: Grant
    Filed: November 15, 2022
    Date of Patent: May 7, 2024
    Assignee: Taoglas Group Holdings Limited
    Inventors: Jeffrey Keith Shamblin, Vladimir Furlan, Patrick Carl Frank
  • Patent number: 11970409
    Abstract: Per- and polyfluoroalkyl substances (PFAS) are destroyed by oxidation in supercritical conditions. PFAS in water can be concentrated and prepared for destruction in a pretreatment phase. Following annihilation of the PFAS in supercritical conditions to levels below 5 parts per trillion (ppt), the water effluent can be used to recover heat, returned to sub-critical conditions, and then released back into the environment.
    Type: Grant
    Filed: November 21, 2022
    Date of Patent: April 30, 2024
    Assignee: Revive Environmental Technology, LLC
    Inventors: Lindy E. Dejarme, Kavitha Dasu, Russell R. Sirabian, Jeffrey Ellis, Dan Garbark, Nathan Bryant, John Tallarico, Joseph Casciano, Slawomir Winecki, David Holley, Joshua James, Keith Brown, Doug Hendry, Darwin Argumedo, Aaron Frank, Christopher Gordon Scheitlin, Michael M. Miller
  • Patent number: 11813339
    Abstract: This invention relates to radioactive, bone-seeking, pharmaceutical compositions that are administered multiple times to a patient, have a lower impurity profile, a longer shelf life, and are less expensive to prepare.
    Type: Grant
    Filed: February 6, 2018
    Date of Patent: November 14, 2023
    Assignee: IGL PHARMA, INC.
    Inventors: Jaime Simon, R. Keith Frank
  • Publication number: 20230165817
    Abstract: A method is described for providing acute symptomatic relief to a subject with Parkinson's Disease (PD) or other CNS disorders resulting from dopamine deficiency in the brain comprising administering to said subject an amount of a ketogenic material sufficient to produce a ketosis in the subject sufficient to provide therapeutic benefit in such neurological disorders. Preferred materials produce a ketosis is such that the total concentration of acetoacetate and (R)-3-hydroxybutyrate in the blood of the subject is raised to between 0.1 and 30 mM.
    Type: Application
    Filed: July 12, 2022
    Publication date: June 1, 2023
    Inventors: Keith Frank MARTIN, David John HEAL
  • Publication number: 20220409751
    Abstract: A targeted radiopharmaceutical of chemical Formula I, below, is disclosed wherein Q+3 is a trivalent radioactive isotope ion; M is a proton (H+), an ammonium ion or an alkali metal ion; ā€œgā€ is a number that is 1 to about 12; the boxed mAb MNPR-101 represents the chemically-bonded humanized mAb MNPR-101; and Y? is an optional anion present in an amount needed to balance the ionic charge. A pharmaceutical composition that comprises a theranostic effective amount of a Formula I targeted radiopharmaceutical dissolved or dispersed in a pharmaceutically acceptable diluent is also disclosed, as are a method for treating and/or diagnosing a mammalian host having a disease, disorder or condition characterized by undesired angiogenesis, tumor growth and/or tumor metastasis. A targeted pro-radiopharmaceutical construct similar to that of Formula I but without the radioisotope (Formula III) is also contemplated.
    Type: Application
    Filed: May 20, 2022
    Publication date: December 29, 2022
    Applicants: Northstar Medical Technologies, LLC, Monopar Therapeutics Inc
    Inventors: Andrew MAZAR, James T. HARVEY, R. Keith FRANK, Jaime SIMON, Jason ROGERS
  • Publication number: 20220378956
    Abstract: A targeted radiopharmaceutical comprising a targeting species chemically-bonded to a PCTA-chelated Q+3 trivalent radioactive ion of Formula I is disclosed. Six of R1 through R7 are H and the seventh is a reacted functionality, Z, that forms the chemical bond with the targeting species, T. ā€œgā€ is a number whose average value is 1 to about 12. X1, X2, and X3, are substituent groups that can coordinate to the Q+3 ion and/or help neutralize the ionic charge. Anion Y? is optionally present to balance the ionic charge. A pharmaceutical composition comprising a theranostic effective amount of a targeted radiopharmaceutical of Formula I in a pharmaceutically acceptable diluent is also contemplated, as are a method for treating and/or diagnosing a mammalian host having a disease, disorder or condition characterized by undesired angiogenesis, tumor growth and/or tumor metastasis.
    Type: Application
    Filed: May 20, 2022
    Publication date: December 1, 2022
    Applicants: Northstar Medical Technologies LLC, Monopar Therapeutics Inc.
    Inventors: James T. HARVEY, Andrew MAZAR, R. Keith FRANK, Jaime SIMON, Jason ROGERS
  • Publication number: 20220347133
    Abstract: A method is provided for treating a patient suffering from apoptosis of tissue comprising administering to that subject a therapeutically effective amount of one or more ketogenic compounds such that a physiological ketosis is produced sufficient to arrest said apoptosis. Preferably the apoptosis is of cerebral tissue such as that associated with acute intractible seizures, particularly with status epilepticus. The method is also applicable to apoptosis associated with administration of topic stuimuli for treatment of cancer, that produced by viral infections, autoimmune diseases or Aquired Immuno Defficiency Syndrome. The ketosis produced is a state in which levels of one or both of acetoacetate and (R)-3-hydroxybutyrate concentrations in the mood of the subject such that their total concentration in the blood is elevated above the normal fed levels to between 0.1 and 30 mM.
    Type: Application
    Filed: March 14, 2022
    Publication date: November 3, 2022
    Inventors: Keith Frank MARTIN, David John HEAL, Elizabeth JAGGER
  • Publication number: 20220347134
    Abstract: A method is provided for treating a subject in need of therapy for attention deficit hyperactivity disorder (ADHD) and related CNS disorder symptoms of impaired learning, impaired planning, impaired problem solving, impulsiveness, attention deficit and aggression comprising administering to said subject an amount of a ketogenic material sufficient to produce a ketosis in the subject sufficient to provide therapeutic benefit in such behavioural disorders. Preferred materials produce a ketosis is such that the total concentration of acetoacetate and (R)-3-hydroxybutyrate in the blood of the subject is raised to between 0.1 and 30 mM.
    Type: Application
    Filed: March 10, 2022
    Publication date: November 3, 2022
    Inventors: Keith Frank MARTIN, David John HEAL
  • Publication number: 20220333366
    Abstract: A method for interconnecting floor drains includes attaching a first elbow fitting to an existing floor drain through an existing floor. A second elbow fitting is attached to a new floor drain that is to extend through a new floor overlying the existing floor. An extension pipe extends between the spaced first and second elbow fittings to create a fluid pathway between the new floor drain and the existing floor drain.
    Type: Application
    Filed: April 1, 2022
    Publication date: October 20, 2022
    Inventor: Keith Frank
  • Publication number: 20220273828
    Abstract: This invention relates to a Kit formulation to prepare a radioactive, bone-seeking, pharmaceutical drug that has high radiochemical purity (RCP) in a fast, facile and reproducible process. The Kit has at least two vials and a two-part buffer system with instructions on how to make the drug formulation in a radiopharmacy. The drug formulations of this invention can be conveniently and reproducibly prepared with better delivery of the drug to mammals, better radiochemical purity of the formulation for use in treating a mammal having bone pain, one or more calcific tumors or needing bone marrow suppression or bone marrow ablation.
    Type: Application
    Filed: May 21, 2022
    Publication date: September 1, 2022
    Applicant: IGL Pharma Inc.
    Inventors: R. Keith Frank, Jaime Simon, Kelli R. Jay
  • Patent number: 11369700
    Abstract: This invention relates to a Kit formulation to prepare a radioactive, bone-seeking, pharmaceutical drug that has high radiochemical purity (RCP) in a fast, facile and reproducible process. The Kit has at least two vials and a two-part buffer system with instructions on how to make the drug formulation in a radiopharmacy. The drug formulations of this invention can be conveniently and reproducibly prepared with better delivery of the drug to mammals, better radiochemical purity of the formulation for use in treating a mammal having bone pain, one or more calcific tumors or needing bone marrow suppression or bone marrow ablation.
    Type: Grant
    Filed: May 4, 2020
    Date of Patent: June 28, 2022
    Assignee: IGL Pharma Inc.
    Inventors: R. Keith Frank, Jaime Simon, Kelli R. Jay
  • Publication number: 20220160666
    Abstract: A method is provided for treating a subject in need of medication as an adjunct to elective surgery, comprising administration of a ketogenic material sufficient to produce a physiologically acceptable ketosis in the patient. Preferably the surgery is selected from the groups consisting of removal or section of tumours, removal of redundant organs such as lymph nodes and appendix, open heart surgery, cosmetic surgery, joint and bone surgery.
    Type: Application
    Filed: November 26, 2021
    Publication date: May 26, 2022
    Inventors: David John HEAL, Keith Frank MARTIN
  • Publication number: 20220139255
    Abstract: A voice therapy mask includes a base that is configured to create a seal against a user's face and a body that forms an air pocket. A positive end-expiratory pressure (PEEP) valve is connected to the body to create a back-pressure in the user's lungs and vocal cords. The mask allows the user to move his or her mouth to perform speech therapy exercises, thereby increasing the range of available vocal cord strengthening exercises.
    Type: Application
    Filed: October 30, 2020
    Publication date: May 5, 2022
    Inventor: Matthew Keith Frank
  • Patent number: 11140800
    Abstract: An apparatus suitable for providing ventilation and electromagnetic interference (EMI) containment for a computing device includes a first strip and a second strip. The first strip is sized to span ventilation openings of a computing device covering. The second strip intersects the first strip while also spanning the ventilation openings. Thus, the first strip and the second strip cooperate to define airflow openings within the ventilation openings, the airflow openings being sized to inhibit EMI from exiting the computing device via the ventilation openings.
    Type: Grant
    Filed: January 23, 2019
    Date of Patent: October 5, 2021
    Assignee: CISCO TECHNOLOGY, INC.
    Inventors: Vic Hong Chia, George Edward Curtis, Adriana del Pilar Rangel, Keith Frank Tharp, Alpesh Umakant Bhobe
  • Patent number: 11126096
    Abstract: A method for correcting misalignments is provided. An alignment for each device of a group of devices mounted on a substrate is determined. An alignment error for the group of devices mounted on the substrate is determined based on the respective alignment for each device. One or more correction factors are calculated based on the alignment error. The alignment error is corrected based on the one or more correction factors.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: September 21, 2021
    Assignee: Onto Innovation, Inc.
    Inventors: Elvino Da Silveira, Keith Frank Best, Wayne Fitzgerald, Jian Lu, Xin Song, J. Casey Donaher, Christopher J. McLaughlin
  • Publication number: 20210138095
    Abstract: This invention relates to radioactive, bone-seeking, pharmaceutical compositions that are administered multiple times to a patient, have a lower impurity profile, a longer shelf life, and are less expensive to prepare.
    Type: Application
    Filed: February 6, 2018
    Publication date: May 13, 2021
    Applicant: IGL Pharma, Inc.
    Inventors: Jaime Simon, R. Keith Frank
  • Publication number: 20210077440
    Abstract: A method is described for providing acute symptomatic relief to a subject with Parkinson's Disease (PD) or other CNS disorders resulting from dopamine deficiency in the brain comprising administering to said subject an amount of a ketogenic material sufficient to produce a ketosis in the subject sufficient to provide therapeutic benefit in such neurological disorders. Preferred materials produce a ketosis is such that the total concentration of acetoacetate and (R)-3-hydroxybutyrate in the blood of the subject is raised to between 0.1 and 30 mM.
    Type: Application
    Filed: August 26, 2020
    Publication date: March 18, 2021
    Inventors: Keith Frank MARTIN, David John Heal
  • Patent number: 10918746
    Abstract: This invention concerns a pharmaceutically-acceptable composition of radioactive metals, which are used for treating various diseases in animals or humans, such as cancer and arthritis.
    Type: Grant
    Filed: January 27, 2020
    Date of Patent: February 16, 2021
    Assignee: IsoTherapeutics Group LLC
    Inventors: David A Wilson, R. Keith Frank, Jaime Simon, Druce K Crump
  • Publication number: 20200261607
    Abstract: This invention relates to a Kit formulation to prepare a radioactive, bone-seeking, pharmaceutical drug that has high radiochemical purity (RCP) in a fast, facile and reproducible process. The Kit has at least two vials and a two-part buffer system with instructions on how to make the drug formulation in a radiopharmacy. The drug formulations of this invention can be conveniently and reproducibly prepared with better delivery of the drug to mammals, better radiochemical purity of the formulation for use in treating a mammal having bone pain, one or more calcific tumors or needing bone marrow suppression or bone marrow ablation.
    Type: Application
    Filed: May 4, 2020
    Publication date: August 20, 2020
    Applicant: IsoTherapeutics Group, LLC
    Inventors: R. Keith Frank, Jaime Simon, Kelli R. Jay
  • Publication number: 20200261494
    Abstract: This invention relates to a solid veterinary formulation and a method for its oral administration to an animal, especially cats or dogs, to remove fluid overload in the animal by using a mixture of a water-absorbing polymer and solid fat, optionally having one or more supplemental ingredients. The fluid overload is caused by congestive heart failure or renal disease. The polymer is capable of absorbing at least 10 times its weight in physiological saline. The polymer and other waste materials are excreted in the feces.
    Type: Application
    Filed: October 30, 2018
    Publication date: August 20, 2020
    Applicant: IsoTherapeutics Group LLC
    Inventors: Jaime Simon, R Keith Frank