Patents by Inventor Keith Freebairn

Keith Freebairn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR SEPARATION OF OLIGONUCLEOTIDE OF INTEREST FROM A MIXTURE
    Publication number: 20170275610
    Abstract: A method for separation of an oligonucleotide from a mixture using a biphasic mobile phase/stationary phase liquid-liquid chromatography system. A first mobile phase contains the oligonucleotide and the stationary phase contains an exchanger substance that removably binds to the target oligonucleotide. The mobile phase is caused to flow in contact with the stationary phase in a liquid-liquid chromatography apparatus such that the oligonucleotide becomes bound to the exchanger substance in the liquid stationary phase. The oligonucleotide is then displaced from the liquid stationary phase into a second liquid mobile phase by means of a displacer substance able to displace the oligonucleotide from the stationary phase into the second mobile phase.
    Type: Application
    Filed: May 9, 2017
    Publication date: September 28, 2017
    Inventors: Nathalie DOUILLET, Keith FREEBAIRN, Hacer GUZLEK, Jane HUBERT, Jean-Hughes RENAULT, Christopher THICKITT
  • PROCESS FOR SEPARATION OF OLIGONUCLEOTIDE OF INTEREST FROM A MIXTURE
    Publication number: 20140213780
    Abstract: The present invention is directed to a method for separation of an oligonucleotide from a mixture using a biphasic mobile phase/stationary phase liquid-liquid chromatography system. A first mobile phase contains the oligonucleotide and the stationary phase contains an exchanger substance that removably binds to the target oligonucleotide. The mobile phase is caused to flow in contact with the stationary phase in a liquid-liquid chromatography apparatus such that the oligonucleotide becomes bound to the exchanger substance in the liquid stationary phase. The oligonucleotide is then displaced from the liquid stationary phase into a second liquid mobile phase by means of a displacer substance able to displace the oligonucleotide from the stationary phase into the second mobile phase.
    Type: Application
    Filed: August 30, 2012
    Publication date: July 31, 2014
    Inventors: Nathalie Douillet, Keith Freebairn, Hacer Guzlek, Jane Hubert, Jean-Hughes Renault, Christopher Thickitt