Patents by Inventor Keith Graham McCullagh

Keith Graham McCullagh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptide linkers for covalent linking polypeptide cell modulators
    Patent number: 6545124
    Abstract: Described is a new class of polypeptide cell modulators characterized by being composed of two covalently linked cell modulators in a linear polypeptide sequence. Such dual function polypeptides have new and particularly useful activities when the component polypeptide cell modulators are interferons, lymphokines or cytotoxins which act through different and specific cell receptors to initiate complementary biological activities. Also described is a peptide linker segment comprising a mouse IgG gamma 2b “hinge” in which the four cysteines of the “hinge” have been converted to serines.
    Type: Grant
    Filed: August 25, 1999
    Date of Patent: April 8, 2003
    Assignee: Pharmacia Corporation
    Inventors: Leslie David Bell, Keith Graham McCullagh, Alan George Porter