Abstract: Provided herein are drug implants comprising a therapeutically active agent for the treatment of disease in a subject. In some cases, the drug implant may comprise a polymer matrix and a therapeutically active agent disposed therein. Additionally, provided are methods for manufacturing the drug implants and methods of treating diseases with the implants. In some cases, the drug implant may comprise bicalutamide, e.g., for use in the treatment of prostate cancer.

Abstract: Described are substituted imidazo[1,2-a]pyrazine compounds, which are coelenterazine analogues, kits comprising the analogues, and methods of using the compounds for the detection of luminescence in luciferase-based assays. Also described are methods from making the compounds, such as a method using aminopyrazine acetophosphonates as synthesis intermediates.

Abstract: Provided herein are drug implants comprising apalutamide for the treatment of disease in a subject. In some cases, the drug implant may comprise a polymer matrix and apalutamide disposed therein. Additionally provided are methods for manufacturing the drug implants and methods of treating diseases with the implants. In some cases, the drug implant may be used for the treatment of a proliferative disease of the prostate.

Abstract: Provided herein are drug implants comprising enzalutamide for the treatment of disease in a subject. In some cases, the drug implant may comprise a polymer matrix and enzalutamide disposed therein. Additionally provided are methods for manufacturing the drug implants and methods of treating diseases with the implants. In some cases, the drug implant may be used for the treatment of a proliferative disease of the prostate.

Abstract: Provided herein are drug implants comprising enzalutamide for the treatment of disease in a subject. In some cases, the drug implant may comprise a polymer matrix and enzalutamide disposed therein. Additionally provided are methods for manufacturing the drug implants and methods of treating diseases with the implants. In some cases, the drug implant may be used for the treatment of a proliferative disease of the prostate.

Abstract: Provided herein are drug implants comprising a therapeutically active agent for the treatment of disease in a subject. In some cases, the drug implant may comprise a polymer matrix and a therapeutically active agent disposed therein. Additionally, provided are methods for manufacturing the drug implants and methods of treating diseases with the implants. In some cases, the drug implant may comprise bicalutamide, e.g., for use in the treatment of prostate cancer.

Abstract: Provided herein are drug implants comprising enzalutamide for the treatment of disease in a subject. In some cases, the drug implant may comprise a polymer matrix and enzalutamide disposed therein. Additionally provided are methods for manufacturing the drug implants and methods of treating diseases with the implants. In some cases, the drug implant may be used for the treatment of a proliferative disease of the prostate.

Abstract: Described herein are formulations, methods, and pH responsive compositions useful for the detection of primary and metastatic tumor tissues.

Abstract: Provided herein are drug implants comprising a therapeutically active agent for the treatment of disease in a subject. In some cases, the drug implant may comprise a polymer matrix and a therapeutically active agent disposed therein. Additionally provided are methods for manufacturing the drug implants and methods of treating diseases with the implants. In some cases, the drug implant may comprise bicalutamide, e.g., for use in the treatment of prostate cancer.

Abstract: Provided herein are drug implants comprising a therapeutically active agent for the treatment of disease in a subject. In some cases, the drug implant may comprise a polymer matrix and a therapeutically active agent disposed therein. Additionally provided are methods for manufacturing the drug implants and methods of treating diseases with the implants. In some cases, the drug implant may comprise bicalutamide, e.g., for use in the treatment of prostate cancer.

Abstract: Provided herein are drug implants comprising a therapeutically active agent for the treatment of disease in a subject. In some cases, the drug implant may comprise a polymer matrix and a therapeutically active agent disposed therein. Additionally provided are methods for manufacturing the drug implants and methods of treating diseases with the implants. In some cases, the drug implant may comprise bicalutamide, e.g., for use in the treatment of prostate cancer.

Abstract: A handheld food storage container including a body having a food storage area and an opening for receiving food items into the food storage area. The container may include a handle mounted to the body, a primary alert device housed in the handle, a secondary alert device housed in the body and a metal detector for detecting metal objects located in the food storage area and for causing the actuation of the primary alert device and the secondary alert device.

Abstract: Provided herein are drug implants comprising a therapeutically active agent for the treatment of disease in a subject. In some cases, the drug implant may comprise a polymer matrix and a therapeutically active agent disposed therein. Additionally provided are methods for manufacturing the drug implants and methods of treating diseases with the implants. In some cases, the drug implant may comprise bicalutamide, e.g., for use in the treatment of prostate cancer.

Abstract: Provided herein are drug implants comprising a therapeutically active agent for the treatment of disease in a subject. In some cases, the drug implant may comprise a polymer matrix and a therapeutically active agent disposed therein. Additionally provided are methods for manufacturing the drug implants and methods of treating diseases with the implants. In some cases, the drug implant may comprise bicalutamide, e.g., for use in the treatment of prostate cancer.

Abstract: Provided herein are drug implants comprising a therapeutically active agent for the treatment of disease in a subject. In some cases, the drug implant may comprise a polymer matrix and a therapeutically active agent disposed therein. Additionally provided are methods for manufacturing the drug implants and methods of treating diseases with the implants. In some cases, the drug implant may comprise bicalutamide, e.g., for use in the treatment of prostate cancer.

Abstract: A handheld food storage container including a body having a food storage area and an opening for receiving food items into the food storage area. The container may include a handle mounted to the body, a primary alert device housed in the handle, a secondary alert device housed in the body and a metal detector for detecting metal objects located in the food storage area and for causing the actuation of the primary alert device and the secondary alert device.

Abstract: Disclosed herein, in certain embodiments, are anti-microbial and anti-inflammatory pharmaceutical compositions comprising an ionic liquid comprising a choline cation and fatty acid anion for use in the treatment of rosacea. In some embodiments, the ionic liquid is further formulated in a solvent or a gel base for topical administration.

Abstract: A mobile phone case is provided having a cover shaped to fit snugly around and cover sides and a back of a mobile phone inserted into the cover, the cover having a flat back portion, and a slit formed in the cover between the flat back portion of the cover and sides of the cover for mounting the mobile phone case to a belt. The flat back portion is configured to open with respect to the sides of the cover along the slit such that the mobile phone case is capable of tightly receiving a belt within the slit between the flat back portion and sides of the case.

Abstract: According to some embodiments, a cryogenic storage tank includes a manway formed in a body of the cryogenic storage tank. An inner manway lid is coupled to an inner wall of the cryogenic storage tank and disposed over at least a portion of the manway. An outer manway lid is coupled to an outer wall of the cryogenic storage tank and disposed over at least a portion of the manway. The inner and outer manway lids are configured to retain pressure within the cryogenic storage tank.

Abstract: A mobile phone case is provided having a cover shaped to fit snugly around and cover sides and a back of a mobile phone inserted into the cover, the cover having a flat back portion, and a slit formed in the cover between the flat back portion of the cover and sides of the cover for mounting the mobile phone case to a belt. The flat back portion is configured to open with respect to the sides of the cover along the slit such that the mobile phone case is capable of tightly receiving a belt within the slit between the flat back portion and sides of the case.