Patents by Inventor Keith John Simons

Keith John Simons has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for fabrication of epinephrine bitartrate nanoparticles and epinephrine bitartrate nanoparticles fabricated thereby
    Patent number: 10682316
    Abstract: The invention provides a composition including epinephrine nanoparticles and methods for therapeutic use of the composition in the treatment of conditions responsive to epinephrine such as a cardiac event or an allergic reaction, particularly anaphylaxis. The epinephrine nanoparticles can be incorporated into orally-disintegrating and fast-disintegrating tablet pharmaceutical formulations and can significantly increase the sublingual bioavailability of epinephrine, and thereby reduce the epinephrine dose required. Additionally, the invention provides methods for fabrication of stabilized epinephrine nanoparticles for use in the described compositions.
    Type: Grant
    Filed: November 22, 2016
    Date of Patent: June 16, 2020
    Assignee: Nova Southeastern University
    Inventors: Mutasem Rawas-Qalaji, Ousama Rachid, Keith John Simons, Estelle Simons, Enrique Nieves
  • EPINEPHRINE NANOPARTICLES, METHODS OF FABRICATION THEREOF, AND METHODS FOR USE THEREOF FOR TREATMENT OF CONDITIONS RESPONSIVE TO EPINEPHRINE
    Publication number: 20120322884
    Abstract: The invention provides a composition including epinephrine nanoparticles and methods for therapeutic use of the composition in the treatment of conditions responsive to epinephrine such as a cardiac event or an allergic reaction, particularly anaphylaxis. The epinephrine nanoparticles can be incorporated into orally-disintegrating and fast-disintegrating tablet pharmaceutical formulations and can significantly increase the sublingual bioavailability of epinephrine, and thereby reduce the epinephrine dose required. Additionally, the invention provides methods for fabrication of stabilized epinephrine nanoparticles for use in the described compositions.
    Type: Application
    Filed: March 1, 2011
    Publication date: December 20, 2012
    Applicants: UNIVERSITY OF MANITOBA, NOVA SOUTHEASTERN UNIVERSITY
    Inventors: Mutasem Rawas-Qalaji, Enrique Nieves, Keith John Simons, Frances Estelle Reed Simons, Ousama Rachid