Patents by Inventor Keith Knisley

Keith Knisley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Implantable encapsulation devices
    Patent number: 12246153
    Abstract: The present disclosure relates to implantable encapsulation devices for housing a biological moiety or a therapeutic device that contains a biological moiety. Particularly, aspects of the present disclosure are directed to an implantable apparatus that includes a distal end, a proximal end, a manifold including at least one access port positioned either at the distal end or the proximal end, and a plurality of containment tubes affixed to the manifold and in fluid communication with the at least one access port. Additionally, the encapsulation device may contain a flush port and a tube that are fluidly connected to the manifold. The containment tubes may contain therein a biological moiety (e.g., cells) or a therapeutic device (e.g. a cell encapsulation member).
    Type: Grant
    Filed: May 19, 2021
    Date of Patent: March 11, 2025
    Assignee: W.L. Gore & Associates, Inc.
    Inventors: Edward H. Cully, Edward Gunzel, Keith Knisley, Greg Rusch, Lauren Zambotti
  • Implantable encapsulation devices
    Patent number: 11938294
    Abstract: The present disclosure relates to implantable encapsulation devices for housing a biological moiety or a therapeutic device that contains a biological moiety. Particularly, aspects of the present disclosure are directed to an implantable apparatus that includes a distal end, a proximal end, a manifold including at least one access port positioned either at the distal end or the proximal end, and a plurality of containment tubes affixed to the manifold and in fluid communication with the at least one access port. Additionally, the encapsulation device may contain a flush port and a tube that are fluidly connected to the manifold. The containment tubes may contain therein a biological moiety (e.g., cells) or a therapeutic device (e.g. a cell encapsulation member).
    Type: Grant
    Filed: January 10, 2022
    Date of Patent: March 26, 2024
    Assignee: W. L. Gore & Associates, Inc.
    Inventors: Edward H. Cully, Edward Gunzel, Keith Knisley, Greg Rusch, Lauren Zambotti
  • IMPLANTABLE ENCAPSULATION DEVICES
    Publication number: 20220126076
    Abstract: The present disclosure relates to implantable encapsulation devices for housing a biological moiety or a therapeutic device that contains a biological moiety. Particularly, aspects of the present disclosure are directed to an implantable apparatus that includes a distal end, a proximal end, a manifold including at least one access port positioned either at the distal end or the proximal end, and a plurality of containment tubes affixed to the manifold and in fluid communication with the at least one access port. Additionally, the encapsulation device may contain a flush port and a tube that are fluidly connected to the manifold. The containment tubes may contain therein a biological moiety (e.g., cells) or a therapeutic device (e.g. a cell encapsulation member).
    Type: Application
    Filed: January 10, 2022
    Publication date: April 28, 2022
    Inventors: Edward H. Cully, Edward Gunzel, Keith Knisley, Greg Rusch, Lauren Zambotti
  • Implantable Encapsulation Devices
    Publication number: 20210268245
    Abstract: The present disclosure relates to implantable encapsulation devices for housing a biological moiety or a therapeutic device that contains a biological moiety. Particularly, aspects of the present disclosure are directed to an implantable apparatus that includes a distal end, a proximal end, a manifold including at least one access port positioned either at the distal end or the proximal end, and a plurality of containment tubes affixed to the manifold and in fluid communication with the at least one access port. Additionally, the encapsulation device may contain a flush port and a tube that are fluidly connected to the manifold. The containment tubes may contain therein a biological moiety (e.g., cells) or a therapeutic device (e.g. a cell encapsulation member).
    Type: Application
    Filed: May 19, 2021
    Publication date: September 2, 2021
    Inventors: Edward H. Cully, Edward Gunzel, Keith Knisley, Greg Rusch, Lauren Zambotti
  • Implantable encapsulation devices
    Patent number: 11052230
    Abstract: The present disclosure relates to implantable encapsulation devices for housing a biological moiety or a therapeutic device that contains a biological moiety. Particularly, aspects of the present disclosure are directed to an implantable apparatus that includes a distal end, a proximal end, a manifold including at least one access port positioned either at the distal end or the proximal end, and a plurality of containment tubes affixed to the manifold and in fluid communication with the at least one access port. Additionally, the encapsulation device may contain a flush port and a tube that are fluidly connected to the manifold. The containment tubes may contain therein a biological moiety (e.g., cells) or a therapeutic device (e.g. a cell encapsulation member).
    Type: Grant
    Filed: November 7, 2017
    Date of Patent: July 6, 2021
    Assignee: W. L. Gore & Associates, Inc.
    Inventors: Edward H. Cully, Edward Gunzel, Keith Knisley, Greg Rusch, Lauren Zambotti
  • Implantable Encapsulation Devices
    Publication number: 20180126134
    Abstract: The present disclosure relates to implantable encapsulation devices for housing a biological moiety or a therapeutic device that contains a biological moiety. Particularly, aspects of the present disclosure are directed to an implantable apparatus that includes a distal end, a proximal end, a manifold including at least one access port positioned either at the distal end or the proximal end, and a plurality of containment tubes affixed to the manifold and in fluid communication with the at least one access port. Additionally, the encapsulation device may contain a flush port and a tube that are fluidly connected to the manifold. The containment tubes may contain therein a biological moiety (e.g., cells) or a therapeutic device (e.g. a cell encapsulation member).
    Type: Application
    Filed: November 7, 2017
    Publication date: May 10, 2018
    Inventors: Edward H. Cully, Edward Gunzel, Keith Knisley, Greg Rusch, Lauren Zambotti