Patents by Inventor Keith Krenek

Keith Krenek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Electronic circuits for analyzing electrogenic cells and related methods
    Patent number: 12174140
    Abstract: Methods and systems for monitoring the activity of electrogenic networks are described. One representative system includes an array of electrode coupled to an analyzer having a stimulator and a receiver. The electrode is placed in contact with an electrogenic cell. The electrodes can be shaped as nanowires, tubes, cavities and/or cones. The analyzer may be configured to operate in a voltage stimulation mode, in which the cells are stimulated via voltages and monitored via current, or in a current stimulation mode, in which the cells are stimulated via currents and monitored via voltages. The analyzers may be arranged as single-stage amplifiers, and may include a feedback loop shared between the stimulation signal path and the sensing signal path. The feedback loop may be arranged to provide overlapping stimulation and sensing of the electrogenic network's cells.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: December 24, 2024
    Assignee: President and Fellows of Harvard College
    Inventors: Donhee Ham, Hongkun Park, Keith Krenek, Tianyang Ye, Jeffrey T. Abbott, Wenxuan Wu
  • ELECTRONIC CIRCUITS FOR ANALYZING ELECTROGENIC CELLS AND RELATED METHODS
    Publication number: 20200292482
    Abstract: Methods and systems for monitoring the activity of electrogenic networks are described. One representative system includes an array of electrode coupled to an analyzer having a stimulator and a receiver. The electrode is placed in contact with an electrogenic cell. The electrodes can be shaped as nanowires, tubes, cavities and/or cones. The analyzer may be configured to operate in a voltage stimulation mode, in which the cells are stimulated via voltages and monitored via current, or in a current stimulation mode, in which the cells are stimulated via currents and monitored via voltages. The analyzers may be arranged as single-stage amplifiers, and may include a feedback loop shared between the stimulation signal path and the sensing signal path. The feedback loop may be arranged to provide overlapping stimulation and sensing of the electrogenic network's cells.
    Type: Application
    Filed: October 30, 2018
    Publication date: September 17, 2020
    Applicant: President and Fellows of Harvard College
    Inventors: Donhee Ham, Hongkun Park, Keith Krenek, Tianyang Ye, Jeffrey T. Abbott, Wenxuan Wu