Patents by Inventor Keith Lorimer

Keith Lorimer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240083856
    Abstract: The present invention provides crystalline forms of (E)-6-(4-Phenylcyclohexyl)-5-(3-trifluoromethylbenzyl)-1H-pyrimidine-2,4-dione, and methods of making and using the same.
    Type: Application
    Filed: August 7, 2023
    Publication date: March 14, 2024
    Inventors: Hazel Joan Hunt, Lorraine Donaghy, Keith Lorimer, Nathan Jay Dixon, Jeffrey Mark Dener
  • Patent number: 11760731
    Abstract: The present invention provides crystalline forms of (E)-6-(4-Phenylcyclohexyl)-5-(3-trifluoromethylbenzyl)-1H-pyrimidine-2,4-dione, and methods of making and using the same.
    Type: Grant
    Filed: December 5, 2022
    Date of Patent: September 19, 2023
    Assignee: Corcept Therapeutics Incorporated
    Inventors: Hazel Joan Hunt, Lorraine Donaghy, Keith Lorimer, Nathan Jay Dixon, Jeffrey Mark Dener
  • Publication number: 20230212128
    Abstract: The present invention provides crystalline forms of (E)-6-(4-Phenylcyclohexyl)-5-(3-trifluoromethylbenzyl)-1H-pyrimidine-2,4-dione, and methods of making and using the same.
    Type: Application
    Filed: December 5, 2022
    Publication date: July 6, 2023
    Inventors: Hazel Joan Hunt, Lorraine Donaghy, Keith Lorimer, Nathan Jay Dixon, Jeffrey Mark Dener
  • Patent number: 11548856
    Abstract: The present invention provides crystalline forms of (E)-6-(4-Phenylcyclohexyl)-5-(3-trifluoromethylbenzyl)-1H-pyrimidine-2,4-dione, and methods of making and using the same.
    Type: Grant
    Filed: May 5, 2021
    Date of Patent: January 10, 2023
    Assignee: Corcept Therapeutics Incorporated
    Inventors: Hazel Joan Hunt, Lorraine Donaghy, Keith Lorimer, Nathan Jay Dixon, Jeffrey Mark Dener
  • Publication number: 20210363112
    Abstract: The present invention provides crystalline forms of (E)-6-(4-Phenylcyclohexyl)-5-(3-trifluoromethylbenzyl)-1H-pyrimidine-2,4-dione, and methods of making and using the same.
    Type: Application
    Filed: May 5, 2021
    Publication date: November 25, 2021
    Inventors: Hazel Joan HUNT, Lorraine DONAGHY, Keith LORIMER, Nathan Jay DIXON, Jeffrey Mark DENER
  • Patent number: 9975921
    Abstract: Crystalline forms of anamorelin which are useful as pharmaceutical agents are disclosed. Methods of production and isolation of these polymorphs and pharmaceutical compositions which include these polymorphs and pharmaceutical methods of treatment are also disclosed. The crystalline polymorphs of the present invention are useful as they act directly on the pituitary gland cells to release growth hormone.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: May 22, 2018
    Assignee: HELSINN HEALTHCARE SA
    Inventors: Keith Lorimer, Seemon H Pines, Bernhard Paul, Benjamin Littler
  • Patent number: 9492425
    Abstract: The disclosure relates to new crystalline forms of genistein. The disclosed crystalline forms include crystalline genistein sodium salt dihydrate; crystalline genistein potassium salt dihydrate; crystalline genistein calcium salt; crystalline genistein magnesium salt; crystalline genistein L-lysine salt; crystalline genistein N-methylglucamine salt; crystalline genistein N-ethylglucamine salt; crystalline genistein diethylamine salt; and crystalline genistein monohydrate. The disclosure also relates to the novel genistein salts represented by these crystalline forms. Therapeutic compositions containing at least one of these crystalline forms of genistein and/or a genistein salt and a pharmaceutically acceptable carrier are described.
    Type: Grant
    Filed: April 20, 2015
    Date of Patent: November 15, 2016
    Assignee: AXCENTUA PHARMACEUTICALS AB
    Inventors: Anders Berkenstam, Stefan Rehnmark, Michael-Robin Witt, Keith Lorimer, Stephen Watt
  • Patent number: 9314471
    Abstract: The invention provides and describes solid state 17?-ethynyl-5?-androstane-3?,17?-diol including amorphous and crystalline forms and specific polymorphic forms thereof. Anhydrates and solvates of 17?-ethynyl-5?-androstane-3?,17?-diol include Form III anhydrate and Form I solvate. The invention further relates to solid and suspension formulations containing 17?-ethynyl-5?-androstane-3?,17?-diol in a described solid state form and use of the formulations to treat cancers or precancers such as prostate cancer or breast cancer in subjects or human patients. The invention also relates to methods to make liquid formulations from solid state forms of 17?-ethynyl-5?-androstane-3?,17?-diol and uses of such formulations in treating the described conditions.
    Type: Grant
    Filed: June 17, 2013
    Date of Patent: April 19, 2016
    Assignee: NEURMEDIX, INC.
    Inventors: Steven K. White, Erin E. Jansen, Keith Lorimer, Brenton Skylar Wolfe
  • Publication number: 20160046667
    Abstract: Crystalline forms of anamorelin which are useful as pharmaceutical agents are disclosed. Methods of production and isolation of these polymorphs and pharmaceutical compositions which include these polymorphs and pharmaceutical methods of treatment are also disclosed. The crystalline polymorphs of the present invention are useful as they act directly on the pituitary gland cells to release growth hormone.
    Type: Application
    Filed: October 30, 2015
    Publication date: February 18, 2016
    Inventors: Keith Lorimer, Seemon H. Pines, Bernhard Paul, Benjamin Littler
  • Publication number: 20150290166
    Abstract: The disclosure relates to new crystalline forms of genistein. The disclosed crystalline forms include crystalline genistein sodium salt dihydrate; crystalline genistein potassium salt dihydrate; crystalline genistein calcium salt; crystalline genistein magnesium salt; crystalline genistein L-lysine salt; crystalline genistein N-methylglucamine salt; crystalline genistein N-ethylglucamine salt; crystalline genistein diethylamine salt; and crystalline genistein monohydrate. The disclosure also relates to the novel genistein salts represented by these crystalline forms. Therapeutic compositions containing at least one of these crystalline forms of genistein and/or a genistein salt and a pharmaceutically acceptable carrier are described.
    Type: Application
    Filed: April 20, 2015
    Publication date: October 15, 2015
    Applicant: AXCENTUA PHARMACEUTICALS AB
    Inventors: Anders BERKENSTAM, Stefan REHNMARK, Michael-Robin WITT, Keith LORIMER, Stephen WATT
  • Publication number: 20150203474
    Abstract: This invention relates to: a) compounds and salts thereof that, inter alia, inhibit HCV; (b) intermediates useful for the preparation of such compounds and salts; (c) composition comprising such compounds and salts; (d) methods for preparing such intermediates, compounds, salts, and composition; (e) method of use of such compounds, salts, and compositions; and (f) kits comprising such compounds, salts, and composition.
    Type: Application
    Filed: February 13, 2013
    Publication date: July 23, 2015
    Inventors: Keith Lorimer, Leping Li, Min Zhong, Anna Muchnik
  • Patent number: 9012495
    Abstract: The disclosure relates to new crystalline forms of genistein. The disclosed crystalline forms include crystalline genistein sodium salt dihydrate; crystalline genistein potassium salt dihydrate; crystalline genistein calcium salt; crystalline genistein magnesium salt; crystalline genistein L-lysine salt; crystalline genistein N-methylglucamine salt; crystalline genistein N-ethylglucamine salt; crystalline genistein diethylamine salt; and crystalline genistein monohydrate. The disclosure also relates to the novel genistein salts represented by these crystalline forms. Therapeutic compositions containing at least one of these crystalline forms of genistein and/or a genistein salt and a pharmaceutically acceptable carrier are described.
    Type: Grant
    Filed: December 11, 2009
    Date of Patent: April 21, 2015
    Assignee: Axcentua Pharmaceuticals AB
    Inventors: Anders Berkenstam, Stefan Rehnmark, Michael-Robin Witt, Keith Lorimer, Stephen Watt
  • Patent number: 8975410
    Abstract: This invention relates to novel polymorphs of (HO)2NO2(C6H)—(C2N2O)—(C5N)(CH3)2Cl2O, to processes for their preparation, and to pharmaceutical compositions containing said novel polymorphs as active pharmaceutical ingredient.
    Type: Grant
    Filed: March 16, 2009
    Date of Patent: March 10, 2015
    Assignee: BIAL—Portela & CA., S.A.
    Inventors: David Alexander Learmonth, Keith Lorimer, Kevin Wayne Meyer, Tibor Eszenyi, Álmosné Kovách
  • Publication number: 20140194510
    Abstract: The subject invention provides a solid dispersion of rasagiline citrate, a composition and a process for the manufacture thereof.
    Type: Application
    Filed: March 10, 2014
    Publication date: July 10, 2014
    Applicant: Teva Pharmaceutical Industries Ltd.
    Inventors: Keith Lorimer, David Engers
  • Patent number: 8691872
    Abstract: The subject invention provides a solid dispersion of rasagiline citrate, a composition and a process for the manufacture thereof.
    Type: Grant
    Filed: July 27, 2011
    Date of Patent: April 8, 2014
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Keith Lorimer, David Engers
  • Publication number: 20130345184
    Abstract: The invention provides and describes solid state 17?-ethynyl-5?-androstane-3?,17?-diol including amorphous and crystalline forms and specific polymorphic forms thereof. Anhydrates and solvates of 17?-ethynyl-5?-androstane-3?,17?-diol include Form III anhydrate and Form I solvate. The invention further relates to solid and suspension formulations containing 17?-ethynyl-5?-androstane-3?,17?-diol in a described solid state form and use of the formulations to treat cancers or precancers such as prostate cancer or breast cancer in subjects or human patients. The invention also relates to methods to make liquid formulations from solid state forms of 17?-ethynyl-5?-androstane-3?,17?-diol and uses of such formulations in treating the described conditions.
    Type: Application
    Filed: June 17, 2013
    Publication date: December 26, 2013
    Inventors: Steven K. White, Erin E. Jansen, Keith Lorimer, Brenton Skylar Wolfe
  • Publication number: 20130345455
    Abstract: The invention provides and describes solid state 17?-ethynyl-5?-androstane-3?,17?-diol including amorphous and crystalline forms and specific polymorphic forms thereof. Anhydrates and solvates of 17?-ethynyl-5?-androstane-3?,17?-diol include Form III anhydrate and Form I solvate. The invention further relates to solid and suspension formulations containing 17?-ethynyl-5?-androstane-3?,17?-diol in a described solid state form and use of the formulations to treat cancers or precancers such as prostate cancer or breast cancer in subjects or human patients. The invention also relates to methods to make liquid formulations from solid state forms of 17?-ethynyl-5?-androstane-3?,17?-diol and uses of such formulations in treating the described conditions.
    Type: Application
    Filed: June 17, 2013
    Publication date: December 26, 2013
    Inventors: Steven K. White, Erin E. Jansen, Keith Lorimer, Brenton Skylar Wolfe
  • Publication number: 20130281701
    Abstract: Crystalline forms of anamorelin which are useful as pharmaceutical agents are disclosed. Methods of production and isolation of these polymorphs and pharmaceutical compositions which include these polymorphs and pharmaceutical methods of treatment are also disclosed. The crystalline polymorphs of the present invention are useful as they act directly on the pituitary gland cells to release growth hormone.
    Type: Application
    Filed: June 17, 2013
    Publication date: October 24, 2013
    Applicant: Helsinn Therapeutics (U.S.), Inc.
    Inventors: Keith Lorimer, Marcia Philipson, Bernhard Paul, Benjamin Littler
  • Patent number: 8518922
    Abstract: The invention provides and describes solid state 17?-ethynyl-5?-androstane-3?,17?-diol including amorphous and crystalline forms and specific polymorphic forms thereof. Anhydrates and solvates of 17?-ethynyl-5?-androstane-3?,17?-diol include Form III anhydrate and Form I solvate. The invention further relates to solid and suspension formulations containing 17?-ethynyl-5?-androstane-3?,17?-diol in a described solid state form and use of the formulations to treat cancers or precancers such as prostate cancer or breast cancer in subjects or human patients. The invention also relates to methods to make liquid formulations from solid state forms of 17?-ethynyl-5?-androstane-3?,17?-diol and uses of such formulations in treating the described conditions.
    Type: Grant
    Filed: February 12, 2009
    Date of Patent: August 27, 2013
    Assignee: Harbor Therapeutics, Inc.
    Inventors: Steven White, Erin Olson, Keith Lorimer, Brenton Skylar Wolfe
  • Patent number: 8466173
    Abstract: Crystalline polymorphs of (3R)-1-(2-methylalanyl-D-tryptophyl)-3-(phenylmethyl)-3-piperidinecarboxylic acid 1,2,2-trimethylhydrazide which are useful as pharmaceutical agents are disclosed. Methods of production and isolation of these polymorphs and pharmaceutical compositions which include these polymorphs and pharmaceutical methods of treatment are also disclosed. The crystalline polymorphs of the present invention are useful as they act directly on the pituitary gland cells to release growth hormone.
    Type: Grant
    Filed: July 6, 2010
    Date of Patent: June 18, 2013
    Assignee: Helsinn Therapeutics (U.S.), Inc.
    Inventors: Keith Lorimer, Seemon H. Pines, Paul Bernhard, Benjamin Littler