Patents by Inventor Keith M. Davies

Keith M. Davies has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Targeted delivery of antimicrobial agents
    Patent number: 9849189
    Abstract: A cationic antimicrobial peptide (CAMP) conjugate is disclosed. The CAMP conjugate may be made by identifying a suitable carrier peptide; identifying a suitable antimicrobial agent; creating a conjugate by conjugating the peptide with the antimicrobial agent; and evaluating and refining the conjugate. The peptide may be short peptide based on the sequence of a CAMP, such as human ?-defensin-3. The peptide can be directly connected to the antimicrobial agent or through a linker segment. The antimicrobial agent may be connected to the peptide or the linker segment through stable or cleavable bonding. The peptide may carry and facilitate the delivery of the conjugated antimicrobial agent to a microbe.
    Type: Grant
    Filed: May 2, 2016
    Date of Patent: December 26, 2017
    Assignee: George Mason Research Foundation, Inc.
    Inventors: Barney Bishop, Monique van Hoek, Keith M. Davies
  • TARGETED DELIVERY OF ANTIMICROBIAL AGENTS
    Publication number: 20160367692
    Abstract: A cationic antimicrobial peptide (CAMP) conjugate is disclosed. The CAMP conjugate may be made by identifying a suitable carrier peptide; identifying a suitable antimicrobial agent; creating a conjugate by conjugating the peptide with the antimicrobial agent; and evaluating and refining the conjugate. The peptide may be short peptide based on the sequence of a CAMP, such as human ?-defensin-3. The peptide can be directly connected to the antimicrobial agent or through a linker segment. The antimicrobial agent may be connected to the peptide or the linker segment through stable or cleavable bonding. The peptide may carry and facilitate the delivery of the conjugated antimicrobial agent to a microbe.
    Type: Application
    Filed: May 2, 2016
    Publication date: December 22, 2016
    Inventors: Barney Bishop, Monique van Hoek, Keith M. Davies
  • Targeted delivery of antimicrobial agents
    Patent number: 8404636
    Abstract: A cationic antimicrobial peptide (CAMP) conjugate is disclosed. The CAMP conjugate may be made by identifying a suitable carrier peptide; identifying a suitable antimicrobial agent; creating a conjugate by conjugating the peptide with the antimicrobial agent; and evaluating and refining the conjugate. The peptide may be short peptide based on the sequence of a CAMP, such as human ?-defensin-3. The peptide can be directly connected to the antimicrobial agent or through a linker segment. The antimicrobial agent may be connected to the peptide or the linker segment through stable or cleavable bonding. The peptide may carry and facilitate the delivery of the conjugated antimicrobial agent to a microbe.
    Type: Grant
    Filed: July 14, 2009
    Date of Patent: March 26, 2013
    Assignee: George Mason Intellectual Properties, Inc.
    Inventors: Barney Bishop, Monique van Hoek, Keith M. Davies
  • Targeted Delivery of Antimicrobial Agents
    Publication number: 20100022750
    Abstract: A cationic antimicrobial peptide (CAMP) conjugate is disclosed. The CAMP conjugate may be made by identifying a suitable carrier peptide; identifying a suitable antimicrobial agent; creating a conjugate by conjugating the peptide with the antimicrobial agent; and evaluating and refining the conjugate. The peptide may be short peptide based on the sequence of a CAMP, such as human ?-defensin-3. The peptide can be directly connected to the antimicrobial agent or through a linker segment. The antimicrobial agent may be connected to the peptide or the linker segment through stable or cleavable bonding. The peptide may carry and facilitate the delivery of the conjugated antimicrobial agent to a microbe.
    Type: Application
    Filed: July 14, 2009
    Publication date: January 28, 2010
    Inventors: Barney Bishop, Monique van Hoek, Keith M. Davies