Patents by Inventor Keith Manning

Keith Manning has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9910960
    Abstract: Methods and systems are presented for indicating the proximity of a process requirement metric to a corresponding system process requirement in a physiological monitor. Metrics are determined based on a received physiological signal, such as a PPG signal. At least one of the metrics is compared to a corresponding system process requirement, such as a threshold, which can be used to trigger a system process, such as an alarm, a recalibration, or a measurement. The proximity of the metric to the corresponding system process requirement is calculated and indicated. Indicating the proximity to a system process requirement may provide valuable information to clinicians and allow them to manually trigger system processes, such as measurements or recalibrations, when a metric is close to a system process requirement for a significant period of time.
    Type: Grant
    Filed: May 20, 2015
    Date of Patent: March 6, 2018
    Assignee: Covidien LP
    Inventors: James Watson, Paul S. Addison, Keith Manning
  • Patent number: 9877651
    Abstract: Systems and method for utilizing energy harvesting techniques to power a battery-less wireless medical sensor to perform intermittent operations are disclosed. The systems may include one or more sensing components configured to generate data related to one or more physiological parameters by performing intermittent measurements on a patient. The systems and method may include wireless communication circuitry configured to wirelessly transmit the data to a monitor. The monitor may be configured to operate with the battery-less wireless medical sensor or may download required operational algorithms if needed. The intermittent measurement and transmission may be asynchronously executed. The systems and method may include a processing device configured to determine when to perform the intermittent measurement and transmit data based at least upon a power source energy level, a rate at which to perform the intermittent measurement and transmit data, a prioritization, or a triggering event.
    Type: Grant
    Filed: March 13, 2015
    Date of Patent: January 30, 2018
    Inventors: James N. Watson, Paul S. Addison, James H. Dripps, George Keith Manning
  • Publication number: 20160262640
    Abstract: Systems and methods are provided for storing event markers. The value of a monitored physiological metric may be monitored and compared to a reference value. A patient monitoring system may compute a difference between a monitored metric and a reference value, and compare the difference to a threshold value to determine whether a physiological event has occurred. Based on the determination, a patient monitoring system may store an event marker, trigger a response, update a metric value, or perform any other suitable function.
    Type: Application
    Filed: May 24, 2016
    Publication date: September 15, 2016
    Inventors: James N. Watson, Paul Stanley Addison, Rakesh Sethi, Keith Manning
  • Patent number: 9357934
    Abstract: Systems and methods are provided for storing event markers. The value of a monitored physiological metric may be monitored and compared to a reference value. A patient monitoring system may compute a difference between a monitored metric and a reference value, and compare the difference to a threshold value to determine whether a physiological event has occurred. Based on the determination, a patient monitoring system may store an event marker, trigger a response, update a metric value, or perform any other suitable function.
    Type: Grant
    Filed: December 1, 2010
    Date of Patent: June 7, 2016
    Assignee: Nellcor Puritan Bennett Ireland
    Inventors: James N. Watson, Paul Stanley Addison, Rakesh Sethi, Keith Manning
  • Patent number: 9259160
    Abstract: Systems and methods are provided for determining when to update a blood pressure measurement. The value of a physiological metric may be monitored and compared to a reference value. A patient monitoring system may compute a difference between a monitored metric and a reference value, and compare the difference to a threshold value to determine whether to update a blood pressure measurement. The threshold value may be constant or variable, and may depend on the monitored metric.
    Type: Grant
    Filed: December 1, 2010
    Date of Patent: February 16, 2016
    Assignee: Nellcor Puritan Bennett Ireland
    Inventors: James N. Watson, Paul Stanley Addison, Rakesh Sethi, Keith Manning
  • Patent number: 9224962
    Abstract: A novel class of saturated or conjugated dendrimers containing at least one strong ?-donating group coordinated to cyclometalated tridentate gold(III) compounds having the chemical structure depicted by generic formula: wherein: (a) [Au] is a cyclometalated tridentate gold(III) group; (b) Unit A is a ?-donating chemical group; (c) Unit B is a central part of the dendrons comprising a branch point of component dendrimers; (d) Unit C is optional surface groups or dendrons of the dendrimers; (e) n=0 or 1.
    Type: Grant
    Filed: February 27, 2013
    Date of Patent: December 29, 2015
    Assignee: The University of Hong Kong
    Inventors: Vivian Wing Wah Yam, Kobe Man Chung Tang, Maggie Mei Yee Chan, Keith Man Chung Wong
  • Publication number: 20150363561
    Abstract: Methods and systems are presented for indicating the proximity of a process requirement metric to a corresponding system process requirement in a physiological monitor. Metrics are determined based on a received physiological signal, such as a PPG signal. At least one of the metrics is compared to a corresponding system process requirement, such as a threshold, which can be used to trigger a system process, such as an alarm, a recalibration, or a measurement. The proximity of the metric to the corresponding system process requirement is calculated and indicated. Indicating the proximity to a system process requirement may provide valuable information to clinicians and allow them to manually trigger system processes, such as measurements or recalibrations, when a metric is close to a system process requirement for a significant period of time.
    Type: Application
    Filed: May 20, 2015
    Publication date: December 17, 2015
    Inventors: James Watson, Paul S. Addison, Keith Manning
  • Patent number: 9180260
    Abstract: An indicator dilution system includes a catheter configured to deliver an indicator to a patient, an injection device configured to deliver the indicator to the catheter, and a connector coupling the injection device to the catheter. The system also includes one or more sensors configured to acquire measurements from components of the system, which may be used to determine the start and end time of the injection of the indicator to the patient. For example, the one or more sensors may be configured to acquire signals relating to a state of the connector, which may be used to determine whether the connector is in an open state to enable flow of the indicator or in a closed state to reduce flow of the indicator.
    Type: Grant
    Filed: August 30, 2013
    Date of Patent: November 10, 2015
    Assignee: Covidien LP
    Inventors: Qiaojian Huang, Youzhi Li, Sarah Hayman, Keith Manning
  • Publication number: 20150257643
    Abstract: Systems and method for utilizing energy harvesting techniques to power a battery-less wireless medical sensor to perform intermittent operations are disclosed. The systems may include one or more sensing components configured to generate data related to one or more physiological parameters by performing intermittent measurements on a patient. The systems and method may include wireless communication circuitry configured to wirelessly transmit the data to a monitor. The monitor may be configured to operate with the battery-less wireless medical sensor or may download required operational algorithms if needed. The intermittent measurement and transmission may be asynchronously executed. The systems and method may include a processing device configured to determine when to perform the intermittent measurement and transmit data based at least upon a power source energy level, a rate at which to perform the intermittent measurement and transmit data, a prioritization, or a triggering event.
    Type: Application
    Filed: March 13, 2015
    Publication date: September 17, 2015
    Inventors: James N. Watson, Paul S. Addison, James H. Dripps, George Keith Manning
  • Patent number: 8987450
    Abstract: In one embodiment, the present invention provides a class of luminescent gold(III) compounds containing a tridentate ligand with one strong ?-donating group. The present invention also provides methods for synthesizing these compounds, as well as uses of these compounds as electrophosphorescent materials in phosphorescent organic light-emitting devices (OLEDs) to provide electroluminescence (EL).
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: March 24, 2015
    Assignee: The University of Hong Kong
    Inventors: Vivian Wing-Wah Yam, Vonika Ka-Man Au, Mei-Yee Chan, Keith Man-Chung Wong, King Chin Yim
  • Publication number: 20150065956
    Abstract: An indicator dilution system includes a catheter configured to deliver an indicator to a patient, an injection device configured to deliver the indicator to the catheter, and a connector coupling the injection device to the catheter. The system also includes one or more sensors configured to acquire measurements from components of the system, which may be used to determine the start and end time of the injection of the indicator to the patient. For example, the one or more sensors may be configured to acquire signals relating to a state of the connector, which may be used to determine whether the connector is in an open state to enable flow of the indicator or in a closed state to reduce flow of the indicator.
    Type: Application
    Filed: August 30, 2013
    Publication date: March 5, 2015
    Applicant: Covidien LP
    Inventors: Qiaojian Huang, Youzhi Li, Sarah Hayman, Keith Manning
  • Publication number: 20150057554
    Abstract: Various methods and systems for blood pressure monitoring are provided. A device for monitoring blood pressure may include a memory storing instructions for receiving one or more signals representative of one or more patient parameters, wherein at least one of the one or more signals comprises a plethysmography signal. The memory also stores instructions for determining a change in a pulse shape metric of the plethysmography signal and determining a change in a blood pressure signal over a period of time based on the one or more signals. The memory also stores instructions for determining a confidence level of the blood pressure signal based at least in part on a correlation between the change in the blood pressure signal and the change in the pulse shape metric over the period of time. The device also includes a processor configured to execute the instructions.
    Type: Application
    Filed: August 23, 2013
    Publication date: February 26, 2015
    Applicant: Covidien LP
    Inventors: James Watson, Keith Manning, Paul S. Addison
  • Publication number: 20130228758
    Abstract: A novel class of saturated or conjugated dendrimers containing at least one strong ?-donating group coordinated to cyclometalated tridentate gold(III) compounds having the chemical structure depicted by generic formula: wherein: (a) [Au] is a cyclometalated tridentate gold(III) group; (b) Unit A is a ?-donating chemical group; (c) Unit B is a central part of the dendrons comprising a branch point of component dendrimers; (d) Unit C is optional surface groups or dendrons of the dendrimers; (e) n=0 or 1.
    Type: Application
    Filed: February 27, 2013
    Publication date: September 5, 2013
    Inventors: Vivian Wing Wah Yam, Kobe Man Chung Tang, Maggie Mei Yee Chan, Keith Man Chung Wong
  • Patent number: 8415473
    Abstract: A class of luminescent gold(III) compounds containing a tridentate ligand with one strong ?-donating group having the chemical structure depicted by generic formula (I): wherein: (a) X is selected from nitrogen; (b) Y and Z selected from carbon; (c) A is cyclic structure derivative of pyridine group; (d) B and C are cyclic structure derivative of phenyl groups; (e) R1 is an optionally substituted carbon donor ligand attached to the gold atom; (f) n is zero, a positive integer or a negative integer.
    Type: Grant
    Filed: June 30, 2009
    Date of Patent: April 9, 2013
    Assignee: Versitech Limited
    Inventors: Vivian Wing-Wah Yam, Vonika Ka-Man Au, Mei-Yee Chan, Keith Man-Chung Wong, Hoi-Sing Kwok
  • Patent number: 8372977
    Abstract: Embodiments of the invention are directed to luminescent gold(III) compounds contains a bidentate ligand with at least one strong ?-donating group, a method of preparation of these compounds and the use of these compounds in organic light emitting devices. The gold(III) compounds have the chemical structure: wherein: X is a nitrogen atom; Y is selected from a carbon or a nitrogen atom; A-B is a substituted or unsubstituted cyclometalating ligand (for Y?C) or diimine ligand (for Y?N); where A and B are cyclic structure derivatives; R1 and R2 are optionally substituted carbon donor ligands attached to the gold atom, with the proviso that R1 and R2 are not —CH3, —CH2SiMe3, mesityl, pentafluorophenyl, —CH2C(O)R?, —CH(R)SO2CH(R)—, —C6H4N?NC6H5, and wherein R1 and R2 can optionally be combined into a bidentate ligand; and n is greater or equal to zero.
    Type: Grant
    Filed: June 24, 2010
    Date of Patent: February 12, 2013
    Assignee: The University of Hong Kong
    Inventors: Vivian Wing-Wah Yam, Vonika Ka-Man Au, Mei-Yee Chan, Keith Man-Chung Wong
  • Patent number: 8309304
    Abstract: The present invention provides a composition for detecting and/or characterizing a multiple-charged biomolecule comprising a charged d8 or d10 metal complex, wherein the metal complex electrostatically binds to the multiple-charged biomolecule to induce aggregation and self-assembly of the metal complex through metal-metal interactions, ? . . . ? interactions, or a combination of both interactions. The present invention further provides assay methods and kits for label-free optical detection and/or characterization of biomolecules carrying multiple charges, e.g., single-stranded nucleic acids, using a composition comprising a charged d8 or d10 metal complex.
    Type: Grant
    Filed: January 21, 2008
    Date of Patent: November 13, 2012
    Assignee: The University of Hong Kong
    Inventors: Vivian Wing-Wah Yam, Cong Yu, Kenneth Hoi-Yiu Chan, Keith Man-Chung Wong
  • Publication number: 20120253141
    Abstract: Systems and methods are provided for passive photoplethysmograph sensing. A patient monitoring system may provide active sensing, passive sensing, or both. In some cases, a patient monitor may determine whether to provide passive or active sensing. Passive photoplethysmograph sensing may be used to determine physiological information such as pulse rate, respiration rate, or other information. Passive photoplethysmograph sensing may allow for reduced power consumption relative to active sensing.
    Type: Application
    Filed: March 31, 2011
    Publication date: October 4, 2012
    Applicant: Nellcor Puritan Bennett Ireland
    Inventors: Paul Stanley Addison, Keith Manning, James N. Watson
  • Publication number: 20120143012
    Abstract: Systems and methods are provided for storing event markers. The value of a monitored physiological metric may be monitored and compared to a reference value. A patient monitoring system may compute a difference between a monitored metric and a reference value, and compare the difference to a threshold value to determine whether a physiological event has occurred. Based on the determination, a patient monitoring system may store an event marker, trigger a response, update a metric value, or perform any other suitable function.
    Type: Application
    Filed: December 1, 2010
    Publication date: June 7, 2012
    Applicant: Nellcor Puritan Bennett Ireland
    Inventors: James N. Watson, Paul Stanley Addison, Rakesh Sethi, Keith Manning
  • Publication number: 20120143067
    Abstract: Systems and methods are provided for determining when to update a blood pressure measurement. The value of a physiological metric may be monitored and compared to a reference value. A patient monitoring system may compute a difference between a monitored metric and a reference value, and compare the difference to a threshold value to determine whether to update a blood pressure measurement. The threshold value may be constant or variable, and may depend on the monitored metric.
    Type: Application
    Filed: December 1, 2010
    Publication date: June 7, 2012
    Applicant: Nellcor Puritan Bennett Ireland
    Inventors: James N. Watson, Paul Stanley Addison, Rakesh Sethi, Keith Manning
  • Patent number: D807531
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: January 9, 2018
    Assignee: YUSEAL LIMITED
    Inventor: Keith Manning