Patents by Inventor Keith MANSFIELD

Keith MANSFIELD has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODULATORS OF ADENO-ASSOCIATED VIRUS TRANSDUCTION AND USES THEREOF
    Publication number: 20250001013
    Abstract: The disclosure provides compositions and methods for modulating transduction efficiency of AAV particles. Specifically, the disclosure provides AAV transduction modulators that modulate genes or gene products associated with AAV transduction efficiency in gene therapies.
    Type: Application
    Filed: November 23, 2022
    Publication date: January 2, 2025
    Inventors: Eloise Hudry, Katie Kubek-Luck, Keith Mansfield
  • BCMA-TARGETING CHIMERIC ANTIGEN RECEPTOR, AND USES THEREOF
    Publication number: 20200371091
    Abstract: The invention provides compositions and methods for treating diseases associated with expression of BCMA. The invention also relates to a method of administering a BCMA-targeting chimeric antigen receptor (CAR) therapy and an additional therapeutic agent.
    Type: Application
    Filed: November 30, 2018
    Publication date: November 26, 2020
    Inventors: Iulian Pruteanu-Malinici, Keith Mansfield, Boris Engels, Jan J. Melenhorst, Adam David Cohen, Edward A. Stadtmauer, Alfred Garfall, Michael C. Milone, Joseph A. Fraietta
  • Organic compounds
    Patent number: 10203327
    Abstract: The present invention relates to modulators of the interaction between G-protein coupled receptor 15(GPR15) and c10orf99. The modulator may be a small chemical molecule, antibody or other therapeutic protein. Methods of medical treatment and methods of identifying modulators are also described.
    Type: Grant
    Filed: October 23, 2014
    Date of Patent: February 12, 2019
    Assignees: Novartis AG, Odega S.A.
    Inventors: Frederic Bassilana, Birgit Uta Baumgarten, Nathalie Marie-Therese Carte, Michel Detheux, Rocco Falchetto, Sebastien Hannedouche, Vincent Lannoy, Keith Mansfield, Klaus Peter Seuwen, Thomas Laurent Henri Suply
  • ORGANIC COMPOUNDS
    Publication number: 20160274110
    Abstract: The present invention relates to modulators of the interaction between G-protein coupled receptor 15(GPR15) and c10orf99. The modulator maybe a small chemical molecule, antibody or other therapeutic protein. Methods of medical treatment and methods of identifying modulators are also described.
    Type: Application
    Filed: October 23, 2014
    Publication date: September 22, 2016
    Applicants: NOVARTIS AG, EUROSCREEN S.A.
    Inventors: Frederic BASSILANA, Birgit Uta BAUMGARTEN, Nathalie Marie-Therese CARTE, Michel DETHEUX, Rocco FALCHETTO, Sebastien HANNEDOUCHE, Vincent LANNOY, Keith MANSFIELD, Klaus Peter SEUWEN, Thomas Laurent Henri Suply