Patents by Inventor Keith McCullagh

Keith McCullagh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RNA Antagonist Compounds for the Modulation of FABP4/AP2
    Publication number: 20110054011
    Abstract: Oligonucleotides directed against the FABP4 gene are developed for modulating the expression of FABP4 protein. The compositions comprise oligonucleotides, particularly antisense oligonucleotides, targeted to nucleic acids encoding FABP4. Methods of using these compounds for modulation of FABP4 expression and for the treatment of diseases associated with over expression of FABP4 are provided. Examples of such diseases are the metabolic syndrome, diabetes, atherosclerosis, and inflammatory states such as arthritis. The oligomer may be composed of deoxyribonucleosides or a nucleic acid analogue such as for example locked nucleic acid (LNA) or a combination thereof.
    Type: Application
    Filed: August 29, 2008
    Publication date: March 3, 2011
    Inventors: Keith McCullagh, Ellen Marie Straarup, Niels Fisker Nielsen