Abstract: Provided herein are drug implants comprising a therapeutically active agent for the treatment of disease in a subject. In some cases, the drug implant may comprise a polymer matrix and a therapeutically active agent disposed therein. Additionally, provided are methods for manufacturing the drug implants and methods of treating diseases with the implants. In some cases, the drug implant may comprise bicalutamide, e.g., for use in the treatment of prostate cancer.

Abstract: A contact arrangement for a Pre-Insertion Resistor (PIR) wherein a control rod is arranged to move a movable contact, against the force of a biasing member, into temporary connection with a PIR. The control rod comprises a tulip with a plurality of resilient fingers and having a first diameter where it is able to mechanically couple to a latching ring on the movable contact, and a second diameter where the tulip is deformed with the fingers deflected inwards, once the resistance to movement exceeds a predetermined value, wherein the latching ring is able to pass over the tulip to decouple the movable contact from the control rod. The contact arrangement is particularly suited for a PIR arranged for connection in parallel to the interrupter of a gas-insulated switchgear (GIS) circuit breaker.

Abstract: The invention concerns a contact arrangement (50) for a Pre-Insertion Resistor (PIR) wherein a control rod (20) is arranged to move a movable contact (30), against the force of a biasing member (18), into temporary connection with a PIR. The control rod (20) comprises a tulip (21) with a plurality of resilient fingers (24) and having a first diameter where it is able to mechanically couple to a latching ring (31) on the movable contact (30), and a second diameter where the tulip (21) is deformed with the fingers (24) deflected inwards, once the resistance to movement exceeds a predetermined value, wherein the latching ring (31) is able to pass over the tulip (21) to decouple the movable contact (30) from the control rod (20). The contact arrangement (50) is particularly suited for a PIR arranged for connection in parallel to the interrupter of a gas-insulated switchgear (GIS) circuit breaker.

Abstract: A manufactured piece of a tank made by casting or molding for a high-voltage circuit breaker is provided. It comprises a hollow body with at least one wall extending longitudinally along a main axis to delimit a cavity with two ends, a top and a bottom; at least one opening in the top of the body; and at least one particle trap in the bottom of the body for collecting particles. The particle trap is a groove extending between two set apart points belonging to a plan perpendicular to the main axis, the groove preferably extending in a plan perpendicular to the main axis.