Patents by Inventor Keith Oberg

Keith Oberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF DRUG FORMULATION BASED ON INCREASING THE AFFINITY OF ACTIVE AGENTS FOR CRYSTALLINE MICROPARTICLE SURFACES
    Publication number: 20230390206
    Abstract: Methods are provided for promoting the adsorption of an active agent to microparticles by modifying the structural properties of the active agent in order to facilitate favorable association to the microparticle.
    Type: Application
    Filed: August 18, 2023
    Publication date: December 7, 2023
    Applicant: MANNKIND Corporation
    Inventors: Mark Hokenson, Keith A. Oberg
  • INSULIN INFUSION SET
    Publication number: 20220226568
    Abstract: Embodiments of devices and methods to maintain preservative concentration in a medication delivered using a medical device are provided. A barrier layer can be used to prevent migration of preservatives. A vent can be used to allow release of preservatives prior to delivery to the patient. An absorbent element can be used to maintain preservative concentration at a desired level. A filter can be used to capture particulates from the medication prior to delivery to a patient.
    Type: Application
    Filed: August 27, 2021
    Publication date: July 21, 2022
    Inventors: Keith A. OBERG, Mark C. ESTES, Kenneth C. HSU, David S. GILLETT
  • METHOD OF DRUG FORMULATION BASED ON INCREASING THE AFFINITY OF ACTIVE AGENTS FOR CRYSTALLINE MICROPARTICLE SURFACES
    Publication number: 20210353544
    Abstract: Methods are provided for promoting the adsorption of an active agent to microparticles by modifying the structural properties of the active agent in order to facilitate favorable association to the microparticle.
    Type: Application
    Filed: July 26, 2021
    Publication date: November 18, 2021
    Applicant: MannKind Corporation
    Inventors: Mark Hokenson, Keith A. Oberg
  • Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces
    Patent number: 11103459
    Abstract: Methods are provided for promoting the adsorption of an active agent to microparticles by modifying the structural properties of the active agent in order to facilitate favorable association to the microparticle.
    Type: Grant
    Filed: October 4, 2018
    Date of Patent: August 31, 2021
    Assignee: MannKind Corporation
    Inventors: Mark Hokenson, Keith A. Oberg
  • Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents
    Patent number: 11013692
    Abstract: Methods are provided for coating crystalline microparticles with an active agent by altering the surface properties of the microparticles in order to facilitate favorable association on the microparticle by the active agent. Types of surface properties that are altered by the disclosed methods include electrostatic properties, hydrophobic properties, and hydrogen bonding properties.
    Type: Grant
    Filed: June 12, 2019
    Date of Patent: May 25, 2021
    Assignee: MannKind Corporation
    Inventors: Keith A. Oberg, Joseph Sulner, Marshall L. Grant
  • Processing blood samples to detect target nucleic acids
    Patent number: 10858690
    Abstract: Provided herein are porous polymer monolith materials and processes that enable integration of blood fractionation, specific nucleic acid amplification and/or detection of nucleic acids from whole blood.
    Type: Grant
    Filed: May 25, 2017
    Date of Patent: December 8, 2020
    Assignee: Monolythix, Inc.
    Inventors: Ivan Rueda, Ian McFadden, Mark D. Dobbs, Victor Shum, Keith A. Oberg, Anthony Spence, Walt Caldwell
  • Processing blood samples to detect target nucleic acids
    Patent number: 10752937
    Abstract: Provided herein are porous polymer monolith materials and processes that enable integration of blood fractionation, specific nucleic acid amplification and/or detection of nucleic acids from whole blood.
    Type: Grant
    Filed: July 28, 2017
    Date of Patent: August 25, 2020
    Assignee: MONOLYTHIX, INC.
    Inventors: Ivan Rueda, Ian McFadden, Mark D. Dobbs, Victor Shum, Keith A. Oberg, Anthony Spence, Walt Caldwell
  • Sample concentration devices
    Patent number: 10570439
    Abstract: The present disclosure relates to a concentrator for concentrating, purifying or otherwise isolating one or more target analytes in a fluid matrix, and related methods, using self-wicking materials, such as monoliths. The present disclosure can be used as a point-of need sample preparation device. The self-contained device can be used for the extraction and concentration of specific target molecules, such as nucleic acids.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: February 25, 2020
    Assignees: Monolythix, Inc., Alfred E. Mann Foundation for Scientific Research
    Inventors: Keith A. Oberg, Anthony Spence, Ivan Rueda, Mark D. Dobbs, Milton Lee
  • MONOLITHS
    Publication number: 20190338100
    Abstract: The present invention relates to a monolith for processing fluid samples, and methods of making and using the monolith. The monolith can contain certain monomers or combinations of monomers that can be polymerized to give a polymeric monolith that can efficiently self-wick fluid. The self-wicking polymeric monolith can be used as a convenient tool for point of care/on site diagnostics and analytics. The monolith is easily stored and transported, comparatively cost-efficient to make, permits good detection of analyte molecules and is readily functionalizable by impregnation of and/or covalently grafting additional chemical moieties to either the whole monolith or in zones.
    Type: Application
    Filed: May 14, 2019
    Publication date: November 7, 2019
    Applicants: Monolythix, Inc., Alfred E. Mann Foundation for Scientific Research
    Inventors: Keith A. Oberg, Mark D. Dobbs, Ekaterina Tkatchouk, Scott P. Layne, Milton Lee
  • METHOD OF DRUG FORMULATION BASED ON INCREASING THE AFFINITY OF CRYSTALLINE MICROPARTICLE SURFACES FOR ACTIVE AGENTS
    Publication number: 20190290586
    Abstract: Methods are provided for coating crystalline microparticles with an active agent by altering the surface properties of the microparticles in order to facilitate favorable association on the microparticle by the active agent. Types of surface properties that are altered by the disclosed methods include electrostatic properties, hydrophobic properties, and hydrogen bonding properties.
    Type: Application
    Filed: June 12, 2019
    Publication date: September 26, 2019
    Inventors: Keith A. Oberg, Joseph Sulner, Marshall L. Grant
  • Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents
    Patent number: 10357459
    Abstract: Methods are provided for coating crystalline microparticles with an active agent by altering the surface properties of the microparticles in order to facilitate favorable association on the microparticle by the active agent. Types of surface properties that are altered by the disclosed methods include electrostatic properties, hydrophobic properties, and hydrogen bonding properties.
    Type: Grant
    Filed: June 21, 2017
    Date of Patent: July 23, 2019
    Assignee: MannKind Corporation
    Inventors: Keith A. Oberg, Joseph Sulner, Marshall L. Grant
  • Monoliths
    Patent number: 10336881
    Abstract: The present invention relates to a monolith for processing fluid samples, and methods of making and using the monolith. The monolith can contain certain monomers or combinations of monomers that can be polymerized to give a polymeric monolith that can efficiently self-wick fluid. The self-wicking polymeric monolith can be used as a convenient tool for point of care/on site diagnostics and analytics. The monolith is easily stored and transported, comparatively cost-efficient to make, permits good detection of analyte molecules and is readily functionalizable by impregnation of and/or covalently grafting additional chemical moieties to either the whole monolith or in zones.
    Type: Grant
    Filed: September 28, 2016
    Date of Patent: July 2, 2019
    Assignees: Alfred E. Mann Foundation for Scientific Research, Monolythix, Inc.
    Inventors: Keith A. Oberg, Mark D. Dobbs, Ekaterina Tkatchouk, Scott P. Layne, Milton Lee
  • METHOD OF DRUG FORMULATION BASED ON INCREASING THE AFFINITY OF ACTIVE AGENTS FOR CRYSTALLINE MICROPARTICLE SURFACES
    Publication number: 20190029961
    Abstract: Methods are provided for promoting the adsorption of an active agent to microparticles by modifying the structural properties of the active agent in order to facilitate favorable association to the microparticle.
    Type: Application
    Filed: October 4, 2018
    Publication date: January 31, 2019
    Inventors: Mark Hokenson, Keith A. Oberg
  • Method of drug formulation
    Patent number: 10143655
    Abstract: Methods are provided for promoting the adsorption of an active agent to microparticles by modifying the structural properties of the active agent in order to facilitate favorable association to the microparticle.
    Type: Grant
    Filed: August 10, 2016
    Date of Patent: December 4, 2018
    Assignee: MannKind Corporation
    Inventors: Mark Hokenson, Keith A. Oberg
  • Valves, valved fluid transfer devices and ambulatory infusion devices including the same
    Patent number: 10004848
    Abstract: Valves, valved fluid transfer devices and ambulatory infusion devices including the same.
    Type: Grant
    Filed: October 8, 2016
    Date of Patent: June 26, 2018
    Assignee: Medallion Therapeutics, Inc.
    Inventors: Susan McConnell, Keith A. Oberg, Lawrence S. Ring, Peter C. Lord
  • Valves, valved fluid transfer devices and ambulatory infusion devices including the same
    Patent number: 9968741
    Abstract: Valves, valved fluid transfer devices and ambulatory infusion devices including the same.
    Type: Grant
    Filed: October 8, 2016
    Date of Patent: May 15, 2018
    Assignee: Medallion Therapeutics, Inc.
    Inventors: Susan McConnell, Keith A. Oberg, Lawrence S. Ring, Peter C. Lord
  • PROCESSING BLOOD SAMPLES TO DETECT TARGET NUCLEIC ACIDS
    Publication number: 20170342464
    Abstract: Provided herein are porous polymer monolith materials and processes that enable integration of blood fractionation, specific nucleic acid amplification and/or detection of nucleic acids from whole blood.
    Type: Application
    Filed: May 25, 2017
    Publication date: November 30, 2017
    Inventors: Ivan Rueda, Ian McFadden, Mark D. Dobbs, Victor Shum, Keith A. Oberg, Anthony Spence, Walt Caldwell
  • PROCESSING BLOOD SAMPLES TO DETECT TARGET NUCLEIC ACIDS
    Publication number: 20170342466
    Abstract: Provided herein are porous polymer monolith materials and processes that enable integration of blood fractionation, specific nucleic acid amplification and/or detection of nucleic acids from whole blood.
    Type: Application
    Filed: July 28, 2017
    Publication date: November 30, 2017
    Inventors: Ivan Rueda, Ian McFadden, Mark D. Dobbs, Victor Shum, Keith A. Oberg, Anthony Spence, Walt Caldwell
  • METHOD OF DRUG FORMULATION BASED ON INCREASING THE AFFINITY OF CRYSTALLINE MICROPARTICLE SURFACES FOR ACTIVE AGENTS
    Publication number: 20170281549
    Abstract: Methods are provided for coating crystalline microparticles with an active agent by altering the surface properties of the microparticles in order to facilitate favorable association on the microparticle by the active agent. Types of surface properties that are altered by the disclosed methods include electrostatic properties, hydrophobic properties, and hydrogen bonding properties.
    Type: Application
    Filed: June 21, 2017
    Publication date: October 5, 2017
    Inventors: Keith A. Oberg, Joseph Sulner, Marshall L. Grant
  • Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents
    Patent number: 9717689
    Abstract: Methods are provided for coating crystalline microparticles with an active agent by altering the surface properties of the microparticles in order to facilitate favorable association on the microparticle by the active agent. Types of surface properties that are altered by the disclosed methods include electrostatic properties, hydrophobic properties, and hydrogen bonding properties.
    Type: Grant
    Filed: February 5, 2016
    Date of Patent: August 1, 2017
    Assignee: MannKind Corporation
    Inventors: Keith A. Oberg, Joseph Sulner, Marshall L. Grant