Patents by Inventor Keith Paige

Keith Paige has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tissue engineered tendons and ligaments
    Patent number: 7914579
    Abstract: Connective tissue, including neo-tendons and ligaments, has been constructed using biodegradable synthetic scaffolds seeded with tenocytes. The scaffolds are preferably formed from biodegradable fibers formed of a polymer such as polyglycolic acid-polylactic acid copolymers, and seeded with cells isolated from autologous tendon or ligament by means of enzymatic digestion or direct seeding into tissue culture dishes from explants. The cell polymer constructs are then surgically transplanted to replace missing segments of functioning tendon or ligament.
    Type: Grant
    Filed: February 9, 2006
    Date of Patent: March 29, 2011
    Assignees: Children's Medical Center Corporation, Massachusetts Institute of Technology
    Inventors: Charles A. Vacanti, Yi Lin Cao, Robert S. Langer, Joseph P. Vacanti, Keith Paige, Joseph Upton
  • Tissue engineered tendons and ligaments
    Publication number: 20070005139
    Abstract: Connective tissue, including neo-tendons and ligaments, has been constructed using biodegradable synthetic scaffolds seeded with tenocytes. The scaffolds are preferably formed from biodegradable fibers formed of a polymer such as polyglycolic acid-polylactic acid copolymers, and seeded with cells isolated from autologous tendon or ligament by means of enzymatic digestion or direct seeding into tissue culture dishes from explants. The cell polymer constructs are then surgically transplanted to replace missing segments of functioning tendon or ligament.
    Type: Application
    Filed: February 9, 2006
    Publication date: January 4, 2007
    Inventors: Charles Vacanti, Yi Cao, Robert Langer, Joseph Vacanti, Keith Paige, Joseph Upton
  • Tissue engineered tendons and ligaments
    Publication number: 20050060033
    Abstract: Connective tissue, including neo-tendons and ligaments, has been constructed using biodegradable synthetic scaffolds seeded with tenocytes. The scaffolds are preferably formed from biodegradable fibers formed of a polymer such as polyglycolic acid-polylactic acid copolymers, and seeded with cells isolated from autologous tendon or ligament by means of enzymatic digestion or direct seeding into tissue culture dishes from explants. The cell polymer constructs are then surgically transplanted to replace missing segments of functioning tendon or ligament.
    Type: Application
    Filed: August 6, 2004
    Publication date: March 17, 2005
    Inventors: Charles Vacanti, Yi Cao, Robert Langer, Joseph Vacanti, Keith Paige, Joseph Upton
  • Tissue engineered tendons and ligaments
    Patent number: 6840962
    Abstract: Connective tissue, including neo-tendons and ligaments, has been constructed using biodegradable synthetic scaffolds seeded with tenocytes. The scaffolds are preferably formed from biodegradable fibers formed of a polymer such as polyglycolic acid-polylactic acid copolymers, and seeded with cells isolated from autologous tendon or ligament by means of enzymatic digestion or direct seeding into tissue culture dishes from explants. The cell polymer constructs are then surgically transplanted to replace missing segments of functioning tendon or ligament.
    Type: Grant
    Filed: September 25, 2000
    Date of Patent: January 11, 2005
    Assignees: Massachusetts Institute of Technology, Children's Medical Center Corporation
    Inventors: Charles A. Vacanti, Yi Lin Cao, Robert S. Langer, Joseph P. Vacanti, Keith Paige, Joseph Upton
  • Tissue engineered tendons and ligaments
    Patent number: 6123727
    Abstract: Connective tissue, including neo-tendons and ligaments, has been constructed using biodegradable synthetic scaffolds seeded with tenocytes. The scaffolds are preferably formed from biodegradable fibers formed of a polymer such as polyglycolic acid-polylactic acid copolymers, and seeded with cells isolated from autologous tendon or ligament by means of enzymatic digestion or direct seeding into tissue culture dishes from explants. The cell polymer constructs are then surgically transplanted to replace missing segments of functioning tendon or ligament.
    Type: Grant
    Filed: August 4, 1997
    Date of Patent: September 26, 2000
    Assignees: Massachusetts Institute of Technology, Cambridge Childern's Medical Center Corproration
    Inventors: Charles A. Vacanti, Yi Lin Cao, Robert S. Langer, Joseph P. Vacanti, Keith Paige, Joseph Upton