Patents by Inventor Keith R. Cromack

Keith R. Cromack has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080145402
    Abstract: A medical device comprises a supporting structure capable of containing or supporting a pharmaceutically acceptable carrier or excipient, which carrier or excipient may contain one or more therapeutic agents or substances, with the carrier preferably including a coating on the surface thereof, and the coating containing the therapeutic substances, such as, for example, drugs. Supporting structures for the medical devices that are suitable for use in this invention include, but are not limited to, coronary stents, peripheral stents, catheters, arterio-venous grafts, by-pass grafts, and drug delivery balloons used in the vasculature. Drugs that are suitable for use in this invention include, but are not limited to drugs of Formula (I).
    Type: Application
    Filed: March 3, 2008
    Publication date: June 19, 2008
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Karl W. Mollison, Angela M. LeCaptain, Sandra E. Burke, Keith R. Cromack, Peter J. Tarcha, Yen-Chih J. Chen, John L. Toner
  • Patent number: 7378105
    Abstract: A system and compositions including zotarolimus and paclitaxel are disclosed, as well as methods of delivery, wherein the drugs have effects that complement each other. Medical devices are disclosed which include supporting structures that include at least one pharmaceutically acceptable carrier or excipient, which carrier or excipient can include one or more therapeutic agents or substances, with the carrier including at least one coating on the surface thereof, and the coating associated with the therapeutic substances, such as, for example, drugs. Supporting structures for the medical devices that are suitable for use in this invention include, but are not limited to, coronary stents, peripheral stents, catheters, arterio-venous grafts, by-pass grafts, and drug delivery balloons used in the vasculature.
    Type: Grant
    Filed: August 15, 2006
    Date of Patent: May 27, 2008
    Assignee: Abbott Laboratories
    Inventors: Sandra E. Burke, Keith R. Cromack, Matthew Mack, John L. Toner
  • Patent number: 7357942
    Abstract: A system and compositions including zotarolimus and paclitaxel are disclosed, as well as methods of delivery, wherein the drugs have effects that complement each other. Medical devices are disclosed which include supporting structures that include at least one pharmaceutically acceptable carrier or excipient, which carrier or excipient can include one or more therapeutic agents or substances, with the carrier including at least one coating on the surface thereof, and the coating associated with the therapeutic substances, such as, for example, drugs. Supporting structures for the medical devices that are suitable for use in this invention include, but are not limited to, coronary stents, peripheral stents, catheters, arterio-venous grafts, by-pass grafts, and drug delivery balloons used in the vasculature.
    Type: Grant
    Filed: August 15, 2006
    Date of Patent: April 15, 2008
    Assignee: Abbott Laboratories
    Inventors: Sandra E. Burke, Keith R. Cromack, Matthew Mack, John L. Toner
  • Patent number: 6890546
    Abstract: A medical device comprising a supporting structure having a coating on the surface thereof, the coating containing a therapeutic substance, such as, for example, a drug. Supporting structures for the medical devices that are suitable for use in this invention include, but are not limited to, coronary stents, peripheral stents, catheters, arterio-venous grafts, by-pass grafts, and drug delivery balloons used in the vasculature.
    Type: Grant
    Filed: September 10, 2001
    Date of Patent: May 10, 2005
    Assignee: Abbott Laboratories
    Inventors: Karl W. Mollison, Angela M. LeCaptain, Sandra E. Burke, Keith R. Cromack, Peter J. Tarcha
  • Publication number: 20040234573
    Abstract: A medical device comprising a supporting structure capable of containing or supporting a pharmaceutically acceptable carrier or excipient, which carrier or excipient may contain one or more therapeutic agents or substances, with the carrier preferably including a coating on the surface thereof, and the coating containing the therapeutic substances, such as, for example, drugs. Supporting structures for the medical devices that are suitable for use in this invention include, but are not limited to, coronary stents, peripheral stents, catheters, arterio-venous grafts, by-pass grafts, and drug delivery balloons used in the vasculature. Drugs that are suitable for use in this invention include, but are not limited to Formula (I).
    Type: Application
    Filed: March 5, 2004
    Publication date: November 25, 2004
    Inventors: Karl W. Mollison, Angela M. LeCaptain, Sandra E. Burke, Keith R. Cromack, Peter J. Tarcha, Yen-Chih J. Chen, John L. Toner
  • Publication number: 20040180039
    Abstract: A medical device having a hydration inhibitor for controlled delivery of a beneficial agent and methods of manufacturing of the same. The medical device includes an interventional component loaded with a beneficial agent having a first LogP value, the beneficial agent being associated with a hydration inhibitor to control the elution rate of at least part of the beneficial agent, the hydration inhibitor having a second LogP value which is greater than the first LogP value.
    Type: Application
    Filed: March 9, 2004
    Publication date: September 16, 2004
    Inventors: John L. Toner, Keith R. Cromack
  • Publication number: 20040048932
    Abstract: The present invention relates to an anesthetic composition containing a fluoroether compound and a physiologically acceptable Lewis acid inhibitor. This composition exhibits improved stability and does not readily degrade in the presence of a Lewis acid.
    Type: Application
    Filed: June 26, 2003
    Publication date: March 11, 2004
    Inventors: Christopher Bieniarz, Steve H. Chang, Keith R. Cromack, Shuyen L. Huang, Toshikazu Kawai, Manami Kobayashi, David Loffredo, Rajagopalan Raghavan, Earl R. Speicher, Honorate A. Stelmach
  • Patent number: 6677492
    Abstract: The present invention relates to an anesthetic composition containing a fluoroether compound and a physiologically acceptable Lewis acid inhibitor. This composition exhibits improved stability and does not readily degrade in the presence of a Lewis acid.
    Type: Grant
    Filed: July 3, 2002
    Date of Patent: January 13, 2004
    Assignee: Abbott Laboratories
    Inventors: Christopher Bieniarz, Steve H. Chang, Keith R. Cromack, Shuyen L. Huang, Toshikazu Kawai, Manami Kobayashi, David Loffredo, Rajagopalan Raghavan, Earl R. Speicher, Honorats A. Stelmach
  • Publication number: 20030200963
    Abstract: A pharmaceutical product. The pharmaceutical product includes a container constructed from a material containing one or more of polypropylene, polyethylene, and ionomeric resins. The container defines an interior space. A volume of a fluoroether-containing inhalation anesthetic is contained in the interior space defined by the container.
    Type: Application
    Filed: April 4, 2003
    Publication date: October 30, 2003
    Inventors: Mary Jane Flament-Garcia, Keith R. Cromack, David Loffredo, Rajagopalan Raghavan, George M. Ramsay, Earl R. Speicher
  • Publication number: 20030129215
    Abstract: A medical device comprising a supporting structure having a coating on the surface thereof, the coating containing a therapeutic substance, such as, for example, a drug. Supporting structures for the medical devices that are suitable for use in this invention include, but are not limited to, coronary stents, peripheral stents, catheters, arterio-venous grafts, by-pass grafts, and drug delivery balloons used in the vasculature.
    Type: Application
    Filed: September 6, 2002
    Publication date: July 10, 2003
    Applicant: T-RAM, Inc.
    Inventors: Karl W. Mollison, Angela M. LeCaptain, Sandra E. Burke, Keith R. Cromack, Peter J. Tarcha, Yen-Chih J. Chen, John L. Toner
  • Publication number: 20030130359
    Abstract: The present invention relates to an anesthetic composition containing a fluoroether compound and a physiologically acceptable Lewis acid inhibitor. This composition exhibits improved stability and does not readily degrade in the presence of a Lewis acid.
    Type: Application
    Filed: July 3, 2002
    Publication date: July 10, 2003
    Inventors: Christopher Bieniarz, Steve H. Chang, Keith R. Cromack, Shuyen L. Huang, Toshikazu Kawai, Manami Kobayashi, David Loffrado, Rajagopalan Raghavan, Earl R. Speicher, Honorate A. Stelmach
  • Patent number: 6558679
    Abstract: A pharmaceutical product. The pharmaceutical product includes a container constructed from a material containing one or more of polypropylene, polyethylene, and ionomeric resins. The container defines an interior space. A volume of a fluoroether-containing inhalation anesthetic is contained in the interior space defined by the container.
    Type: Grant
    Filed: December 19, 2000
    Date of Patent: May 6, 2003
    Assignee: Abbott Laboratories
    Inventors: Mary Jane Flament-Garcia, Keith R. Cromack, David Loffredo, Rajagopalan Raghavan, George M. Ramsay, Earl R. Speicher
  • Publication number: 20020123505
    Abstract: A medical device comprising a supporting structure having a coating on the surface thereof, the coating containing a therapeutic substance, such as, for example, a drug. Supporting structures for the medical devices that are suitable for use in this invention include, but are not limited to, coronary stents, peripheral stents, catheters, arterio-venous grafts, by-pass grafts, and drug delivery balloons used in the vasculature.
    Type: Application
    Filed: September 10, 2001
    Publication date: September 5, 2002
    Inventors: Karl W. Mollison, Angela M. LeCaptain, Sandra E. Burke, Keith R. Cromack, Peter J. Tarcha
  • Patent number: 6444859
    Abstract: The present invention relates to an anesthetic composition containing a fluoroether compound and a physiologically acceptable Lewis acid inhibitor. This composition exhibits improved stability and does not readily degrade in the presence of a Lewis acid.
    Type: Grant
    Filed: August 8, 2001
    Date of Patent: September 3, 2002
    Assignees: Abbott Laboratories, Central Glass Company LTD
    Inventors: Christopher Bieniarz, Steve H. Chang, Keith R. Cromack, Shuyen L. Huang, Toshikazu Kawai, Manami Kobayashi, David Loffredo, Rajagopalan Raghavan, Earl R. Speicher, Honorate A. Stelmach
  • Publication number: 20020016373
    Abstract: The present invention relates to an anesthetic composition containing a fluoroether compound and a physiologically acceptable Lewis acid inhibitor. This composition exhibits improved stability and does not readily degrade in the presence of a Lewis acid.
    Type: Application
    Filed: August 8, 2001
    Publication date: February 7, 2002
    Inventors: Christopher Bieniarz, Steve H. Chang, Keith R. Cromack, Shuyen L. Huang, Toshikazu Kawai, Manami Kobayashi, David Loffredo, Rajagopalan Raghavan, Earl R. Speicher, Honorate A. Stelmach
  • Patent number: 6288127
    Abstract: The present invention relates to an anesthetic composition containing a fluoroether compound and a physiologically acceptable Lewis acid inhibitor. This composition exhibits improved stability and does not readily degrade in the presence of a Lewis acid.
    Type: Grant
    Filed: November 23, 1999
    Date of Patent: September 11, 2001
    Assignee: Abbott Laboratories & Central Glass Co LTD
    Inventors: Christopher Bieniarz, Steve H. Chang, Keith R. Cromack, Shuyen L. Huang, Toshikazu Kawai, Manami Kobayashi, David Loffredo, Rajagopalan Raghavan, Earl R. Speicher, Honorate A. Stelmach
  • Publication number: 20010000729
    Abstract: A pharmaceutical product. The pharmaceutical product includes a container constructed from a material containing one or more of polypropylene, polyethylene, and ionomeric resins. The container defines an interior space. A volume of a fluoroether-containing inhalation anesthetic is contained in the interior space defined by the container.
    Type: Application
    Filed: December 19, 2000
    Publication date: May 3, 2001
    Inventors: Mary Jane Flament-Garcia, Keith R. Cromack, David Loffredo, Rajagopalan Raghavan, George M. Ramsay, Earl R. Speicher
  • Patent number: 6162443
    Abstract: A pharmaceutical product. The pharmaceutical product includes a container constructed from a material containing one or more of polypropylene, polyethylene, and ionomeric resins. The container defines an interior space. A volume of a fluoroether-containing inhalation anesthetic is contained in the interior space defined by the container.
    Type: Grant
    Filed: December 4, 1998
    Date of Patent: December 19, 2000
    Assignee: Abbott Laboratories
    Inventors: Mary Jane Flament-Garcia, Keith R. Cromack, David Loffredo, Rajagopalan Raghavan, George M. Ramsay, Earl R. Speicher
  • Patent number: 6083514
    Abstract: A pharmaceutical product. The pharmaceutical product includes a container constructed from a material containing polymethylpentene. The container defines an interior space. A volume of a fluoroether-containing inhalation anesthetic is contained in the interior space defined by the container.
    Type: Grant
    Filed: January 9, 1998
    Date of Patent: July 4, 2000
    Assignee: Abbott Laboratories
    Inventors: Steve H. Chang, Keith R. Cromack, Mary Jane Flament-Garcia, Joan Garapolo, David Loffredo, Rajagopalan Raghavan, George M. Ramsay, Patrick Rice, Jeffrey Setesak
  • Patent number: 6074668
    Abstract: A pharmaceutical product. The pharmaceutical product includes a container constructed from a material containing polyethylene napthalate. The container defines an interior space. A volume of a fluoroether-containing inhalation anesthetic is contained in the interior space defined by the container.
    Type: Grant
    Filed: January 9, 1998
    Date of Patent: June 13, 2000
    Assignee: Abbott Laboratories
    Inventors: Mary Jane Flament-Garcia, Steve H. Chang, Keith R. Cromack, Joan Garapolo, David Loffredo, Rajagopalan Raghavan, George M. Ramsay, Patrick Rice, Jeffrey Setesak