Patents by Inventor Keith R. Mulholland

Keith R. Mulholland has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heteroaryl compounds used as pharmaceuticals
    Patent number: 5620992
    Abstract: A compound of formula (I) ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, X.sub.1, X.sub.2, x, Y and Z are as defined in the specification are useful in the treatment or prophylaxis of gastrointestinal disorders, cardiovascular disorders and CNS disorders.
    Type: Grant
    Filed: March 10, 1995
    Date of Patent: April 15, 1997
    Assignee: SmithKline Beecham plc
    Inventors: Francis D. King, Laramie M. Gaster, Keith R. Mulholland
  • 5-HT.sub.4 receptor antagonists
    Patent number: 5580885
    Abstract: The use of a compound of formula (I) or pharmaceutically acceptable salt thereof, in which X.sub.1 --(CH.sub.2).sub.x --X.sub.2 forms a 5-7 membered ring wherein: X.sub.1 is O or S; X.sub.2 is O, S, NR or NRCO wherein R is hydrogen or C.sub.1-6 alkyl; x is 1, 2 or 3; Y is O or NH; Z is sub-formula (a), (b) or (c) in the manufacture of a medicament for use in the treatment of gastrointestinal disorders, cardiovascular disorders and CNS disorders.
    Type: Grant
    Filed: July 28, 1994
    Date of Patent: December 3, 1996
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Francis D. King, Laramie M. Gaster, Keith R. Mulholland, Shirley K. Rahman, Paul A. Wyman, Gareth J. Sanger, Kay A. Wardle, Gordon S. Baxter, Guy A. Kennett, Alberto J. Kauman
  • 5-HT.sub.4 receptor antagonists
    Patent number: 5492919
    Abstract: The invention provides the use of a compound of formula (I) ##STR1## wherein A, E, F, U, X, Y, Z, are as defined in the specification, or a pharmaceutically acceptable salt thereof, for the treatment of diarrhea predominant irritable bowel syndrome.
    Type: Grant
    Filed: July 6, 1994
    Date of Patent: February 20, 1996
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Gareth J. Sanger, Francis D. King, Gordon S. Baxter, Laramie M. Gaster, Alberto J. Kaumann, Guy A. Kennett, Keith R. Mulholland, Mythily Vimal, Kay A. Wardle, Paul A. Wyman, Rodney C. Young