Patents by Inventor Keith R. Olewine

Keith R. Olewine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10910123
    Abstract: Methods for isolating Pb and/or Pb isotopes from various sources are provided. Compositions comprising Pb and/or Pb isotopes free of certain amounts of various contaminants are also provided.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: February 2, 2021
    Assignee: Lantheus Medical Imaging, Inc.
    Inventor: Keith R. Olewine
  • Publication number: 20190131025
    Abstract: Methods for isolating Pb and/or Pb isotopes from various sources are provided. Compositions comprising Pb and/or Pb isotopes free of certain amounts of various contaminants are also provided.
    Type: Application
    Filed: December 20, 2018
    Publication date: May 2, 2019
    Applicant: Lantheus Medical Imaging, Inc.
    Inventor: Keith R. Olewine
  • Patent number: 10199130
    Abstract: Methods for isolating Pb and/or Pb isotopes from various sources are provided. Compositions comprising Pb and/or Pb isotopes free of certain amounts of various contaminants are also provided.
    Type: Grant
    Filed: April 15, 2015
    Date of Patent: February 5, 2019
    Assignee: Lantheus Medical Imaging, Inc.
    Inventor: Keith R. Olewine
  • Publication number: 20170040074
    Abstract: Methods for isolating Pb and/or Pb isotopes from various sources are provided. Compositions comprising Pb and/or Pb isotopes free of certain amounts of various contaminants are also provided.
    Type: Application
    Filed: April 15, 2015
    Publication date: February 9, 2017
    Applicant: Lantheus Medical Imaging, Inc.
    Inventor: Keith R. Olewine
  • Patent number: 7138643
    Abstract: Methods and apparatus for separating ions of metallic elements are provided. Preferred methods utilize a hydrophobic chelating extractant, such as an organophosphorus compound, adsorbed onto carbon or graphite fibers in the form of felt. Also described is a new thallium-201 generator that comprises a column containing an acidic organophosphorus extractant adsorbed on carbon or graphite fibers, and a yttrium-90 generator system comprised of two extraction columns designed to selectively absorb yttrium-90 at different pH, to enable the separation of yttrium-90 from strontium-90. The two columns are connected in series for stepwise separation. The yttrium-90 product is freed from residual strontium-90 and metal contaminants and can be eluted from the second column with dilute acid, acetate buffer, water or saline for labeling biological targeted molecules. The new generator system provides rapid and efficient separation of yttrium-90 and is amenable to both scale-up and automation.
    Type: Grant
    Filed: January 22, 2004
    Date of Patent: November 21, 2006
    Assignee: Bristol-Myers Squibb Pharma Company
    Inventors: Robert E. Lewis, Fu-Min Su, Timothy A. Lane, Keith R. Olewine, Peter S. Holton
  • Publication number: 20040164025
    Abstract: Methods and apparatus for separating ions of metallic elements are provided. Preferred methods utilize a hydrophobic chelating extractant, such as an organophosphorus compound, adsorbed onto carbon or graphite fibers in the form of felt. Also described is a new thallium-201 generator that comprises a column containing an acidic organophosphorus extractant adsorbed on carbon or graphite fibers, and a yttrium-90 generator system comprised of two extraction columns designed to selectively absorb yttrium-90 at different pH, to enable the separation of yttrium-90 from strontium-90. The two columns are connected in series for stepwise separation. The yttrium-90 product is freed from residual strontium-90 and metal contaminants and can be eluted from the second column with dilute acid, acetate buffer, water or saline for labeling biological targeted molecules. The new generator system provides rapid and efficient separation of yttrium-90 and is amenable to both scale-up and automation.
    Type: Application
    Filed: January 22, 2004
    Publication date: August 26, 2004
    Inventors: Robert E. Lewis, Fu-Min Su, Timothy A. Lane, Keith R. Olewine, Peter S. Holton
  • Publication number: 20030152502
    Abstract: Methods and apparatus for separating ions of metallic elements are provided. Preferred methods utilize a hydrophobic chelating extractant, such as an organophosphorus compound, adsorbed onto carbon or graphite fibers in the form of felt. Also described is a new thallium-201 generator that comprises a column containing an acidic organophosphorus extractant adsorbed on carbon or graphite fibers, and a yttrium-90 generator system comprised of two extraction columns designed to selectively absorb yttrium-90 at different pH, to enable the separation of yttrium-90 from strontium-90. The two columns are connected in series for stepwise separation. The yttrium-90 product is freed from residual strontium-90 and metal contaminants and can be eluted from the second column with dilute acid, acetate buffer, water or saline for labeling biological targeted molecules. The new generator system provides rapid and efficient separation of yttrium-90 and is amenable to both scale-up and automation.
    Type: Application
    Filed: December 17, 2002
    Publication date: August 14, 2003
    Inventors: Robert E. Lewis, Fu-Min Su, Timothy A. Lane, Keith R. Olewine, Peter S. Holton
  • Patent number: 6391279
    Abstract: Novel radioactive seeds for brachytherapy and a reproducible method of manufacturing the seeds is described, wherein the seeds contain either Pd-103 or I-125 disposed within a cured resin matrix.
    Type: Grant
    Filed: November 13, 1998
    Date of Patent: May 21, 2002
    Assignee: Bristol-Myers Squibb Pharma Company
    Inventors: Prahlad R. Singh, Gerald P. Tercho, Jack N. Wentz, Keith R. Olewine