Patents by Inventor Keith Roger Bley

Keith Roger Bley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-(substituted-phenyl)amino-imidazoline derivatives
    Patent number: 7141584
    Abstract: This invention relates to IP receptor antagonists selected from the group of compounds represented by Formula I: where: R1 is a group represented by formula (A), (B) or (C); and other substituents as defined in the specification, and their pharmaceutically acceptable salts or crystal forms thereof; and pharmaceutical compositions containing them; and methods for their use as therapeutic agents.
    Type: Grant
    Filed: December 9, 2003
    Date of Patent: November 28, 2006
    Assignee: Roche Palo Alto LLC
    Inventors: Keith Roger Bley, Robin Douglas Clark, Alam Jahangir, Bruce Andrew Kowalczyk, Francisco Javier Lopez-Tapia, Alexander Victor Muehldorf, Counde O'Yang, Thomas Weitao Sun
  • Thiophenylaminoimidazolines as IP antagonists
    Patent number: 7078401
    Abstract: Methods for treatment of IP antagonist mediated diseases or conditions by administration to a subject in need thereof a compound of formula (I) wherein R1, R2, A and X are as defined herein. Also disclosed are compounds and related compositions.
    Type: Grant
    Filed: July 9, 2004
    Date of Patent: July 18, 2006
    Assignee: Roche Palo Alto LLC
    Inventors: Keith Roger Bley, Robin Douglas Clark, Alam Jahangir
  • 2-(substituted-phenyl)amino-imidazoline derivatives
    Publication number: 20040122053
    Abstract: This invention relates to IP receptor antagonists selected from the group of compounds represented by Formula I: 1
    Type: Application
    Filed: December 9, 2003
    Publication date: June 24, 2004
    Inventors: Keith Roger Bley, Robin Douglas Clark, Alam Jahangir, Bruce Andrew Kowalczyk, Francisco Javier Lopez-Tapia, Alexander Victor Muehldorf, Counde O'Yang, Thomas Weitao Sun
  • 2-(substituted-phenyl)amino-imidazoline derivatives
    Patent number: 6693200
    Abstract: This invention relates to IP receptor antagonists selected from the group of compounds represented by Formula I: where: R1 is a group represented by formula (A), (B) or (C); and other substituents as defined in the specification, and their pharmaceutically acceptable salts or crystal forms thereof; and pharmaceutical compositions containing them; and methods for their use as therapeutic agents.
    Type: Grant
    Filed: April 29, 2003
    Date of Patent: February 17, 2004
    Assignee: Syntex (U.S.A.) LLC
    Inventors: Keith Roger Bley, Robin Douglas Clark, Alam Jahangir, Bruce Andrew Kowalczyk, Francisco Javier Lopez-Tapia, Alexander Victor Muehldorf, Counde O'Yang, Thomas Weitao Sun
  • 2-(Substituted-phenyl)amino-imidazoline derivatives
    Publication number: 20030229123
    Abstract: This invention relates to IP receptor antagonists selected from the group of compounds represented by Formula I: 1
    Type: Application
    Filed: April 29, 2003
    Publication date: December 11, 2003
    Inventors: Keith Roger Bley, Robin Douglas Clark, Alam Jahangir, Bruce Andrew Kowalczyk, Francisco Javier Lopez-Tapia, Alexander Victor Muehldorf, Counde O'Yang, Thomas Weitao Sun
  • 2-(substituted-phenyl)amino-imidazoline derivatives
    Patent number: 6596876
    Abstract: This invention relates to IP receptor antagonists selected from the group of compounds represented by Formula I: where: R1 is a group represented by formula (A), (B) or (C);  and other substituents as defined in the specification, and their pharmaceutically acceptable salts or crystal forms thereof; and pharmaceutical compositions containing them; and methods and their use as therapeutic agents.
    Type: Grant
    Filed: May 31, 2002
    Date of Patent: July 22, 2003
    Assignee: Syntex (U.S.A.) LLC
    Inventors: Keith Roger Bley, Robin Douglas Clark, Alam Jahangir, Bruce Andrew Kowalczyk, Francisco Javier Lopez-Tapia, Alexander Victor Muehldorf, Counde O'Yang, Thomas Weitao Sun
  • 2-(substituted-phenyl)amino-imidazoline derivatives
    Publication number: 20030036655
    Abstract: This invention relates to IP receptor antagonists selected from the group of compounds represented by Formula I: 1
    Type: Application
    Filed: May 31, 2002
    Publication date: February 20, 2003
    Inventors: Keith Roger Bley, Robin Douglas Clark, Alam Jahangir, Bruce Andrew Kowalczyk, Francisco Javier Lopez-Tapia, Alexander Victor Muehldorf, Counde O'Yang, Thomas Weitao Sun
  • 2-(substituted-phenyl)amino-imidazoline derivatives
    Patent number: 6472536
    Abstract: This invention relates to IP receptor antagonists selected from the group of compounds represented by Formula I: where: R1 is a group represented by formula (A), (B) or (C); and other substituents as defined in the specification, and their pharmaceutically acceptable salts or crystal forms thereof; and pharmaceutical compositions containing them; and methods for their use as therapeutic agents.
    Type: Grant
    Filed: September 19, 2000
    Date of Patent: October 29, 2002
    Assignee: Syntex (U.S.A.) LLC
    Inventors: Keith Roger Bley, Robin Douglas Clark, Alam Jahangir, Bruce Andrew Kowalczyk, Francisco Javier Lopez-Tapia, Alexander Victor Muehldorf, Counde O'Yang, Thomas Weitao Sun
  • 2-(substituted-phenyl)amino-imidazoline derivatives
    Patent number: 6184242
    Abstract: This invention relates to IP receptor antagonists selected from the group of compounds represented by Formula I: where: R1 is a group represented by formula (A), (B) or (C); and other substituents as defined in the specification, and their pharmaceutically acceptable salts or crystal forms thereof; and pharmaceutical compositions containing them; and methods for their use as therapeutic agents.
    Type: Grant
    Filed: August 20, 1998
    Date of Patent: February 6, 2001
    Assignee: Syntex USA (LLC)
    Inventors: Keith Roger Bley, Robin Douglas Clark, Alam Jahangir, Bruce Andrew Kowalczyk, Francisco Javier Lopez-Tapia, Alexander Victor Muehldorf, Counde O'Yang, Thomas Weitao Sun