Patents by Inventor Keith S. Bahjat

Keith S. Bahjat has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS USING LISTERIA FOR ENHANCING IMMUNOGENICITY BY PRIME BOOST
    Publication number: 20190015488
    Abstract: Provided herein are prime-boost regimens and materials used therein. The prime-boost regimens enhance the immune response to a target antigen. The vaccines used for boost are comprised of recombinant attenuated metabolically active Listeria that encodes an expressible antigen that is cross-reactive with the target antigen. In some examples, the immune response is a cellular immune response.
    Type: Application
    Filed: January 29, 2018
    Publication date: January 17, 2019
    Applicant: ADURO BIOTECH, INC.
    Inventors: Thomas W. Dubensky, Jr., Dirk G. Brockstedt, Meredith Lai Ling Leong, Keith S. Bahjat
  • Methods and compositions using for enhancing immunogenicity by prime boost
    Patent number: 9878024
    Abstract: Provided herein are prime-boost regimens and materials used therein. The prime-boost regimens enhance the immune response to a target antigen. The vaccines used for boost are comprised of recombinant attenuated metabolically active Listeria that encodes an expressible antigen that is cross-reactive with the target antigen. In some examples, the immune response is a cellular immune response.
    Type: Grant
    Filed: November 25, 2015
    Date of Patent: January 30, 2018
    Assignee: ADURO BIOTECH, INC.
    Inventors: Thomas W. Dubensky, Jr., Dirk G. Brockstedt, Meredith Lai Ling Leong, Keith S. Bahjat
  • METHODS AND COMPOSITIONS USING LISTERIA FOR ENHANCING IMMUNOGENICITY BY PRIME BOOST
    Publication number: 20160175415
    Abstract: Provided herein are prime-boost regimens and materials used therein. The prime-boost regimens enhance the immune response to a target antigen. The vaccines used for boost are comprised of recombinant attenuated metabolically active Listeria that encodes an expressible antigen that is cross-reactive with the target antigen. In some examples, the immune response is a cellular immune response.
    Type: Application
    Filed: November 25, 2015
    Publication date: June 23, 2016
    Inventors: Thomas W. Dubensky, JR., Dirk G. Brockstedt, Meredith Lai Ling Leong, Keith S. Bahjat
  • Methods and compositions using listeria for enhancing immunogenicity by prime boost
    Patent number: 9198960
    Abstract: Provided herein are prime-boost regimens and materials used therein. The prime-boost regimens enhance the immune response to a target antigen. The vaccines used for boost are comprised of recombinant attenuated metabolically active Listeria that encodes an expressible antigen that is cross-reactive with the target antigen. In some examples, the immune response is a cellular immune response.
    Type: Grant
    Filed: January 5, 2015
    Date of Patent: December 1, 2015
    Assignee: Aduro Biotech, Inc.
    Inventors: Thomas W. Dubensky, Jr., Dirk G. Brockstedt, Meredith Lai Ling Leong, Keith S. Bahjat
  • Methods and compositions using listeria for adjuvant treatment of cancer
    Patent number: 9161974
    Abstract: Provided herein are prime-boost regimens and materials used therein. The prime-boost regimens enhance the immune response to a target antigen. The vaccines used for boost are comprised of recombinant attenuated metabolically active Listeria that encodes an expressible antigen that is cross-reactive with the target antigen. In some examples, the immune response is a cellular immune response.
    Type: Grant
    Filed: May 23, 2011
    Date of Patent: October 20, 2015
    Assignee: ADURO BIOTECH, INC.
    Inventors: Thomas W. Dubensky, Dirk G. Brockstedt, Meredith Leong, Keith S. Bahjat
  • METHODS AND COMPOSITIONS USING LISTERIA FOR ENHANCING IMMUNOGENICITY BY PRIME BOOST
    Publication number: 20150125485
    Abstract: Provided herein are prime-boost regimens and materials used therein. The prime-boost regimens enhance the immune response to a target antigen. The vaccines used for boost are comprised of recombinant attenuated metabolically active Listeria that encodes an expressible antigen that is cross-reactive with the target antigen. In some examples, the immune response is a cellular immune response.
    Type: Application
    Filed: January 5, 2015
    Publication date: May 7, 2015
    Inventors: Thomas W. Dubensky, JR., Dirk G. Brockstedt, Meredith Lai Ling Leong, Keith S. Bahjat
  • Methods and compositions using for enhancing immunogenicity by prime boost
    Patent number: 8926993
    Abstract: Provided herein are prime-boost regimens and materials used therein. The prime-boost regimens enhance the immune response to a target antigen. The vaccines used for boost are comprised of recombinant attenuated metabolically active Listeria that encodes an expressible antigen that is cross-reactive with the target antigen. In some examples, the immune response is a cellular immune response.
    Type: Grant
    Filed: July 17, 2007
    Date of Patent: January 6, 2015
    Assignee: Aduro Biotech
    Inventors: Thomas W. Dubensky, Jr., Dirk G. Brockstedt, Meredith Leong, Keith S. Bahjat
  • METHODS AND COMPOSITIONS USING LISTERIA FOR ADJUVANT TREATMENT OF CANCER
    Publication number: 20130315950
    Abstract: Provided herein are prime-boost regimens and materials used therein. The prime-boost regimens enhance the immune response to a target antigen. The vaccines used for boost are comprised of recombinant attenuated metabolically active Listeria that encodes an expressible antigen that is cross-reactive with the target antigen. In some examples, the immune response is a cellular immune response.
    Type: Application
    Filed: May 23, 2011
    Publication date: November 28, 2013
    Applicant: ADURO BIOTECH
    Inventors: Thomas W. Dubensky, Dirk G. Brockstedt, Meredith Leong, Keith S. Bahjat
  • Modified free-living microbes, vaccine compositions and methods of use thereof
    Patent number: 7927606
    Abstract: Free-living microbes are provided in which the nucleic acid has been modified so that the microbe is attenuated for proliferation and/or which comprise genetic mutations that attenuate the ability of the microbe to repair its nucleic acid. Methods of using the modified microbes for the loading, activation, and/or maturation of antigen-presenting cells are also provided. Vaccine compositions comprising the modified microbes and/or the antigen-presenting cells and methods of using the vaccines are also provided. The microbes may be further modified to include heterologous antigens, such as tumor antigens or infectious disease antigens, for use as a vaccine against cancer or infectious diseases.
    Type: Grant
    Filed: August 11, 2006
    Date of Patent: April 19, 2011
    Assignee: Aduro Biotech
    Inventors: Thomas W. Dubensky, Jr., Dirk G. Brockstedt, Keith S. Bahjat, John E. Hearst, David N. Cook, William S. Luckett, Jr.
  • METHODS AND COMPOSITIONS USING LISTERIA FOR ENHANCING IMMUNOGENICITY BY PRIME BOOST
    Publication number: 20100233212
    Abstract: Provided herein are prime-boost regimens and materials used therein. The prime-boost regimens enhance the immune response to a target antigen. The vaccines used for boost are comprised of recombinant attenuated metabolically active Listeria that encodes an expressible antigen that is cross-reactive with the target antigen. In some examples, the immune response is a cellular immune response.
    Type: Application
    Filed: July 17, 2007
    Publication date: September 16, 2010
    Applicant: ANZA THERAPEUTICS, INC.
    Inventors: Thomas W. Dubensky, JR., Dirk G. Brockstedt, Meredith Leong, Keith S. Bahjat
  • Modified free-living microbes, vaccine compositions and methods of use thereof
    Publication number: 20080248066
    Abstract: Free-living microbes are provided in which the nucleic acid has been modified so that the microbe is attenuated for proliferation and/or which comprise genetic mutations that attenuate the ability of the microbe to repair its nucleic acid. Methods of using the modified microbes for the loading, activation, and/or maturation of antigen-presenting cells are also provided. Vaccine compositions comprising the modified microbes and/or the antigen-presenting cells and methods of using the vaccines are also provided. The microbes may be further modified to include heterologous antigens, such as tumor antigens or infectious disease antigens, for use as a vaccine against cancer or infectious diseases.
    Type: Application
    Filed: August 11, 2006
    Publication date: October 9, 2008
    Applicant: Cerus Corporation
    Inventors: Thomas W. Dubensky, Dirk G. Brockstedt, Keith S. Bahjat, John E. Hearst, David N. Cook, William S. Luckett