Patents by Inventor Keith Sudheimer
Keith Sudheimer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240341607Abstract: Systems and methods for predicting and treating relapses for neurological conditions in accordance with embodiments of the invention are illustrated. One embodiment includes a method for predicting and treating a clinical neurological condition relapse. The method includes steps for selecting a threshold heart rate variability value for a patient suffering from a clinical neurological condition, monitoring, using a cardiac monitor, the heart rate variability of the patient over time, providing an indicator that a relapse is imminent when the heart rate variability of the patient falls below the threshold heart rate variability value, and treating the patient using a transcranial magnetic stimulation device by applying an accelerated theta burst stimulation protocol where the transcranial magnetic stimulation target is the left prefrontal dorsolateral cortex.Type: ApplicationFiled: April 23, 2024Publication date: October 17, 2024Applicant: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Nolan R. Williams, Keith Sudheimer
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Publication number: 20240206749Abstract: Systems and methods for treatment of neurological conditions using aTBS in accordance with embodiments of the invention are illustrated. One embodiment includes a method for treating neurological conditions, including generating a personalized accelerated theta burst stimulation (aTBS) target representing a location in a patient's brain related to a neurological condition, placing a TMS device relative to the patient's brain such that the focus of the magnetic field is over the aTBS target, applying TMS to the aTBS target according to an aTBS protocol to the brain using the TMS device to alleviate the neurological condition.Type: ApplicationFiled: October 24, 2023Publication date: June 27, 2024Applicant: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Nolan R. Williams, Keith Sudheimer
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Patent number: 11992298Abstract: Systems and methods for predicting and treating relapses for neurological conditions in accordance with embodiments of the invention are illustrated. One embodiment includes a method for predicting and treating a clinical neurological condition relapse. The method includes steps for selecting a threshold heart rate variability value for a patient suffering from a clinical neurological condition, monitoring, using a cardiac monitor, the heart rate variability of the patient over time, providing an indicator that a relapse is imminent when the heart rate variability of the patient falls below the threshold heart rate variability value, and treating the patient using a transcranial magnetic stimulation device by applying an accelerated theta burst stimulation protocol where the transcranial magnetic stimulation target is the left prefrontal dorsolateral cortex.Type: GrantFiled: October 26, 2023Date of Patent: May 28, 2024Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Nolan Williams, Keith Sudheimer
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Publication number: 20240065564Abstract: Systems and methods for predicting and treating relapses for neurological conditions in accordance with embodiments of the invention are illustrated. One embodiment includes a method for predicting and treating a clinical neurological condition relapse. The method includes steps for selecting a threshold heart rate variability value for a patient suffering from a clinical neurological condition, monitoring, using a cardiac monitor, the heart rate variability of the patient over time, providing an indicator that a relapse is imminent when the heart rate variability of the patient falls below the threshold heart rate variability value, and treating the patient using a transcranial magnetic stimulation device by applying an accelerated theta burst stimulation protocol where the transcranial magnetic stimulation target is the left prefrontal dorsolateral cortex.Type: ApplicationFiled: October 26, 2023Publication date: February 29, 2024Applicant: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Nolan Williams, Keith Sudheimer
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Patent number: 11839455Abstract: Systems and methods for treatment of neurological conditions using aTBS in accordance with embodiments of the invention are illustrated. One embodiment includes a method for treating neurological conditions, including generating a personalized accelerated theta burst stimulation (aTBS) target representing a location in a patient's brain related to a neurological condition, placing a TMS device relative to the patient's brain such that the focus of the magnetic field is over the aTBS target, applying TMS to the aTBS target according to an aTBS protocol to the brain using the TMS device to alleviate the neurological condition.Type: GrantFiled: March 13, 2020Date of Patent: December 12, 2023Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Nolan Williams, Keith Sudheimer
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Publication number: 20230210388Abstract: Systems and methods for predicting and treating relapses for neurological conditions in accordance with embodiments of the invention are illustrated. One embodiment includes a method for predicting and treating a clinical neurological condition relapse. The method includes steps for selecting a threshold heart rate variability value for a patient suffering from a clinical neurological condition, monitoring, using a cardiac monitor, the heart rate variability of the patient over time, providing an indicator that a relapse is imminent when the heart rate variability of the patient falls below the threshold heart rate variability value, and treating the patient using a transcranial magnetic stimulation device by applying an accelerated theta burst stimulation protocol where the transcranial magnetic stimulation target is the left prefrontal dorsolateral cortex.Type: ApplicationFiled: December 23, 2022Publication date: July 6, 2023Applicant: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Nolan Williams, Keith Sudheimer
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Patent number: 11534074Abstract: Systems and methods for predicting and treating relapses for neurological conditions in accordance with embodiments of the invention are illustrated. One embodiment includes a method for predicting and treating a clinical neurological condition relapse. The method includes steps for selecting a threshold heart rate variability value for a patient suffering from a clinical neurological condition, monitoring, using a cardiac monitor, the heart rate variability of the patient over time, providing an indicator that a relapse is imminent when the heart rate variability of the patient falls below the threshold heart rate variability value, and treating the patient using a transcranial magnetic stimulation device by applying an accelerated theta burst stimulation protocol where the transcranial magnetic stimulation target is the left prefrontal dorsolateral cortex.Type: GrantFiled: January 11, 2019Date of Patent: December 27, 2022Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Nolan Williams, Keith Sudheimer
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Publication number: 20220202302Abstract: Systems and methods for clinical neuronavigation in accordance with embodiments of the invention are illustrated. One embodiment includes a method for generating a brain stimulation target, including obtaining functional magnetic resonance imaging (fMRI) image data of a patient's brain, were brain imaging data describes neuronal activations within the patient's brain, determining a brain stimulation target by mapping at least one region of interest to the patient's brain, locating functional subregions within the at least one region of interest based on the fMRI image data, determining functional relationships between at least two brain regions of interest, generating parameters for each functional subregion, generating a target quality score for each functional subregion based on the parameters and selecting a brain stimulation target based on its target quality score and the patient's neurological condition.Type: ApplicationFiled: January 3, 2022Publication date: June 30, 2022Applicant: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Nolan Williams, Keith Sudheimer
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Patent number: 11213215Abstract: Systems and methods for clinical neuronavigation in accordance with embodiments of the invention are illustrated. One embodiment includes a method for generating a brain stimulation target, including obtaining functional magnetic resonance imaging (fMRI) image data of a patient's brain, where brain imaging data describes neuronal activations within the patient's brain, determining a brain stimulation target by mapping at least one region of interest to the patient's brain, locating functional subregions within the at least one region of interest based on the fMRI image data, determining functional relationships between at least two brain regions of interest, generating parameters for each functional subregion, generating a target quality score for each functional subregion based on the parameters and selecting a brain stimulation target based on its target quality score and the patient's neurological condition.Type: GrantFiled: July 19, 2019Date of Patent: January 4, 2022Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Nolan Williams, Keith Sudheimer
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Publication number: 20210378531Abstract: Systems and methods for treatment of neurological conditions using implantable neurostimulators in accordance with embodiments of the invention are illustrated. One embodiment includes a method for treating neurological conditions, including obtaining image data of a patient's brain, where the image data describes neuronal activations within the patient's brain, determining a location on the patient's brain to implant a neurostimulator, and surgically implanting a neurostimulator at the location, and applying a stimulation protocol to the brain at the location using the neurostimulator to treat the neurological condition. An additional embodiment includes an implantable neurostimulator configured to apply an aTBS protocol to a patient's brain.Type: ApplicationFiled: May 21, 2021Publication date: December 9, 2021Applicant: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Nolan Williams, Keith Sudheimer
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Patent number: 11013423Abstract: Systems and methods for treatment of neurological conditions using implantable neurostimulators in accordance with embodiments of the invention are illustrated. One embodiment includes a method for treating neurological conditions, including obtaining image data of a patient's brain, where the image data describes neuronal activations within the patient's brain, determining a location on the patient's brain to implant a neurostimulator, and surgically implanting a neurostimulator at the location, and applying a stimulation protocol to the brain at the location using the neurostimulator to treat the neurological condition. An additional embodiment includes an implantable neurostimulator configured to apply an aTBS protocol to a patient's brain.Type: GrantFiled: December 10, 2018Date of Patent: May 25, 2021Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Nolan Williams, Keith Sudheimer
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Publication number: 20200214581Abstract: Systems and methods for treatment of neurological conditions using aTBS in accordance with embodiments of the invention are illustrated. One embodiment includes a method for treating neurological conditions, including generating a personalized accelerated theta burst stimulation (aTBS) target representing a location in a patient's brain related to a neurological condition, placing a TMS device relative to the patient's brain such that the focus of the magnetic field is over the aTBS target, applying TMS to the aTBS target according to an aTBS protocol to the brain using the TMS device to alleviate the neurological condition.Type: ApplicationFiled: March 13, 2020Publication date: July 9, 2020Applicant: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Nolan Williams, Keith Sudheimer
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Patent number: 10595735Abstract: Systems and methods for treatment of neurological conditions using aTBS in accordance with embodiments of the invention are illustrated. One embodiment includes a method for treating neurological conditions, including generating a personalized accelerated theta burst stimulation (aTBS) target representing a location in a patient's brain related to a neurological condition, placing a TMS device relative to the patient's brain such that the focus of the magnetic field is over the aTBS target, applying TMS to the aTBS target according to an aTBS protocol to the brain using the TMS device to alleviate the neurological condition.Type: GrantFiled: December 10, 2018Date of Patent: March 24, 2020Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Nolan Williams, Keith Sudheimer
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Publication number: 20190336018Abstract: Systems and methods for clinical neuronavigation in accordance with embodiments of the invention are illustrated. One embodiment includes a method for generating a brain stimulation target, including obtaining functional magnetic resonance imaging (fMRI) image data of a patient's brain, were brain imaging data describes neuronal activations within the patient's brain, determining a brain stimulation target by mapping at least one region of interest to the patient's brain, locating functional subregions within the at least one region of interest based on the fMRI image data, determining functional relationships between at least two brain regions of interest, generating parameters for each functional subregion, generating a target quality score for each functional subregion based on the parameters and selecting a brain stimulation target based on its target quality score and the patient's neurological condition.Type: ApplicationFiled: July 19, 2019Publication date: November 7, 2019Applicant: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Nolan Williams, Keith Sudheimer
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Patent number: 10449384Abstract: Systems and methods for clinical neuronavigation in accordance with embodiments of the invention are illustrated. One embodiment includes a method for generating a brain stimulation target, including obtaining functional magnetic resonance imaging (fMRI) image data of a patient's brain, were brain imaging data describes neuronal activations within the patient's brain, determining a brain stimulation target by mapping at least one region of interest to the patient's brain, locating functional subregions within the at least one region of interest based on the fMRI image data, determining functional relationships between at least two brain regions of interest, generating parameters for each functional subregion, generating a target quality score for each functional subregion based on the parameters and selecting a brain stimulation target based on its target quality score and the patient's neurological condition.Type: GrantFiled: December 10, 2018Date of Patent: October 22, 2019Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Nolan Williams, Keith Sudheimer
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Publication number: 20190217113Abstract: Systems and methods for treatment of neurological conditions using implantable neurostimulators in accordance with embodiments of the invention are illustrated. One embodiment includes a method for treating neurological conditions, including obtaining image data of a patient's brain, where the image data describes neuronal activations within the patient's brain, determining a location on the patient's brain to implant a neurostimulator, and surgically implanting a neurostimulator at the location, and applying a stimulation protocol to the brain at the location using the neurostimulator to treat the neurological condition. An additional embodiment includes an implantable neurostimulator configured to apply an aTBS protocol to a patient's brain.Type: ApplicationFiled: December 10, 2018Publication date: July 18, 2019Applicant: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Nolan Williams, Keith Sudheimer
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Publication number: 20190217112Abstract: Systems and methods for clinical neuronavigation in accordance with embodiments of the invention are illustrated. One embodiment includes a method for generating a brain stimulation target, including obtaining functional magnetic resonance imaging (fMRI) image data of a patient's brain, were brain imaging data describes neuronal activations within the patient's brain, determining a brain stimulation target by mapping at least one region of interest to the patient's brain, locating functional subregions within the at least one region of interest based on the fMRI image data, determining functional relationships between at least two brain regions of interest, generating parameters for each functional subregion, generating a target quality score for each functional subregion based on the parameters and selecting a brain stimulation target based on its target quality score and the patient's neurological condition.Type: ApplicationFiled: December 10, 2018Publication date: July 18, 2019Applicant: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Nolan Williams, Keith Sudheimer
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Publication number: 20190216342Abstract: Systems and methods for predicting and treating relapses for neurological conditions in accordance with embodiments of the invention are illustrated. One embodiment includes a method for predicting and treating a clinical neurological condition relapse. The method includes steps for selecting a threshold heart rate variability value for a patient suffering from a clinical neurological condition, monitoring, using a cardiac monitor, the heart rate variability of the patient over time, providing an indicator that a relapse is imminent when the heart rate variability of the patient falls below the threshold heart rate variability value, and treating the patient using a transcranial magnetic stimulation device by applying an accelerated theta burst stimulation protocol where the transcranial magnetic stimulation target is the left prefrontal dorsolateral cortex.Type: ApplicationFiled: January 11, 2019Publication date: July 18, 2019Applicant: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Nolan Williams, Keith Sudheimer
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Publication number: 20190217116Abstract: Systems and methods for treatment of neurological conditions using aTBS in accordance with embodiments of the invention are illustrated. One embodiment includes a method for treating neurological conditions, including generating a personalized accelerated theta burst stimulation (aTBS) target representing a location in a patient's brain related to a neurological condition, placing a TMS device relative to the patient's brain such that the focus of the magnetic field is over the aTBS target, applying TMS to the aTBS target according to an aTBS protocol to the brain using the TMS device to alleviate the neurological condition.Type: ApplicationFiled: December 10, 2018Publication date: July 18, 2019Applicant: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Nolan Williams, Keith Sudheimer