Patents by Inventor Keith Turner
Keith Turner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20170234015Abstract: A guard rail system that is assembled from a kit of components that includes bottom rails, top rails and balusters and U-shaped top rail inserts that fit into the underside of the top rails. The tops of the balusters are inserted through the spaced apart holes in the base of the insert. The top rail has a body and a pair of spaced apart legs extending downward from the body. After the system has been assembled the legs engage the uprights of the top rail insert to create a compression fit between the top rail insert and the tops of the balusters.Type: ApplicationFiled: February 12, 2016Publication date: August 17, 2017Inventors: Paul Bizzarri, Jason A. Davoll, Michael A. Gori, Richard Arthur Pearson, II, Ronald Keith Turner
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Patent number: 9554842Abstract: A cryoprobe for use in cryosurgery and other applications comprising a rigid outer tube, an inner coolant inlet tube. a short rigid penetrating segment extending distally from the distal end of the outer tube and a helical-shaped baffle having a heating element disposed about the outer surface of the inlet tube. The baffle is adapted to produce turbulent fluid flow improving heat transfer and is able to warm target tissue during rapid freezing and thawing cycles.Type: GrantFiled: June 9, 2015Date of Patent: January 31, 2017Assignee: Sanarus Technologies, Inc.Inventors: Russell L. DeLonzor, James B. Ross, Mathew J. Nalipinski, Keith Turner, David J. Foster, Tom A. Oakley, Michael R. Cane
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Patent number: 9493770Abstract: Provided herein are methods, and related compositions for identifying a putative essential gene which serves as an antibiotic target in a bacterium, the method, in some embodiments, comprising (a) generating an antibiotic resistant mutant of the bacterium by a method comprising the step of selecting for growth in the presence of an antibiotic to produce an antibiotic resistant mutant clone (AbR mutant); (b) transforming the AbR mutant with one or more essential genes of the bacterium and a transposon which insertionally inactivates bacterial DNA to produce a pool of transposon mutants which are merodiploid for the one or more essential genes; (c) growing bacteria from the merodiploid pool in the presence of different amounts of the antibiotic to produce two or more test cultures; and (d) comparing the distribution of transposon insertions between the test cultures to identify a putative essential gene serving as a target of the antibiotic in the bacterium.Type: GrantFiled: November 4, 2013Date of Patent: November 15, 2016Assignee: DISCUVA LIMITEDInventors: David Hugh Williams, Arthur Keith Turner
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Patent number: 9458392Abstract: In a catalytic treatment process, mercaptans in sour hydrocarbon are oxidized to disulfide oils using an aqueous treatment solution containing a chelated polyvalent metal catalyst, alkali metal hydroxide, and the alkali metal salt of at least one alcohol in a non-dispersive mixing apparatus wherein an upgraded hydrocarbon containing the disulfide oils is produced.Type: GrantFiled: November 3, 2014Date of Patent: October 4, 2016Assignee: MERICHEM COMPANYInventors: Tiejun Zhang, K. Michael Hardy, V. Keith Turner, Ignacio C. Bincaz, Tom Varadi
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Publication number: 20150307873Abstract: Described is a process for producing a mutant bacterium which exhibits improved survival and/or growth under a selected growth condition, the process comprising the steps of: (a) generating a pool of mutant bacteria by transposon mutagenesis with an activating transposon (TnA), wherein the TnA comprises a promoter capable of increasing transcription of a gene at or near its insertion site; (b) growing bacteria from the mutant pool under the selected growth condition and under one or more reference conditions to produce two or more test cultures; and (c) comparing the distribution of TnA insertions between test cultures to identify a first class of genes which are disadvantageous for growth and/or survival under the selected growth condition and a second class of genes which are advantageous for growth and/or survival under the selected growth condition.Type: ApplicationFiled: May 6, 2015Publication date: October 29, 2015Applicant: Bactevo Ltd.Inventors: David Hugh Williams, Arthur Keith Turner, John Richard Wain
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Publication number: 20150265330Abstract: A cryoprobe for use in cryosurgery and other applications comprising a rigid outer tube, an inner coolant inlet tube. a short rigid penetrating segment extending distally from the distal end of the outer tube and a helical-shaped baffle having a heating element disposed about the outer surface of the inlet tube. The baffle is adapted to produce turbulent fluid flow improving heat transfer and is able to warm target tissue during rapid freezing and thawing cycles.Type: ApplicationFiled: June 9, 2015Publication date: September 24, 2015Applicant: Sanarus Technologies, Inc.Inventors: Russell L. DeLonzor, James B. Ross, Mathew J. Nalipinski, Keith Turner, David J. Foster, Tom A. Oakley, Michael R. Cane
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Patent number: 9050072Abstract: A cryoprobe for use in cryosurgery and other applications comprising a rigid outer tube, an inner coolant inlet tube. a short rigid penetrating segment extending distally from the distal end of the outer tube and a helical-shaped baffle having a heating element disposed about the outer surface of the inlet tube. The baffle is adapted to produce turbulent fluid flow improving heat transfer and is able to warm target tissue during rapid freezing and thawing cycles.Type: GrantFiled: December 3, 2013Date of Patent: June 9, 2015Assignee: Sanarus Technologies, Inc.Inventors: Russell L. DeLonzor, James B. Ross, Mathew J. Nalipinski, Keith Turner, David J. Foster, Tom A. Oakley, Michael R. Cane
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Publication number: 20150048006Abstract: In a catalytic treatment process, mercaptans in sour hydrocarbon are oxidized to disulfide oils using an aqueous treatment solution containing a chelated polyvalent metal catalyst, alkali metal hydroxide, and the alkali metal salt of at least one alcohol in a non-dispersive mixing apparatus wherein an upgraded hydrocarbon containing the disulfide oils is produced.Type: ApplicationFiled: November 3, 2014Publication date: February 19, 2015Inventors: Tiejun Zhang, K. Michael Hardy, V. Keith Turner, Ignacio C. Bincaz, Tom Varadi
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Patent number: 8900446Abstract: In a catalytic treatment process, mercaptans in sour hydrocarbon are oxidized to disulfide oils using an aqueous treatment solution containing a chelated polyvalent metal catalyst, alkali metal hydroxide, and the alkali metal salt of at least one alcohol in a non-dispersive mixing apparatus wherein an upgraded hydrocarbon containing the disulfide oils is produced.Type: GrantFiled: January 31, 2011Date of Patent: December 2, 2014Assignee: Merichem CompanyInventors: Tiejun Zhang, K. Michael Hardy, V. Keith Turner, Ignacio C. Bincaz, Tom Varadi
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Publication number: 20140163539Abstract: A cryoprobe for use in cryosurgery and other applications comprising a rigid outer tube, an inner coolant inlet tube. a short rigid penetrating segment extending distally from the distal end of the outer tube and a helical-shaped baffle having a heating element disposed about the outer surface of the inlet tube. The baffle is adapted to produce turbulent fluid flow improving heat transfer and is able to warm target tissue during rapid freezing and thawing cycles.Type: ApplicationFiled: December 3, 2013Publication date: June 12, 2014Applicant: Sanarus Technologies, LLCInventors: Russell L. DeLonzor, James B. Ross, Mathew J. Nalipinski, Keith Turner, David J. Foster, Tom A. Oakley, Michael R. Cane
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Publication number: 20140141979Abstract: Disclosed is a method for identifying an essential gene which serves as an antibiotic target in a bacterium, the method comprising the steps of: (a) generating a pool of mutant bacteria by transposon mutagenesis with an activating transposon (TnA), wherein the TnA comprises a promoter such that transposon insertion into bacterial DNA increases the transcription of a gene at or near the insertion site; (b) growing bacteria from the mutant pool in the presence of different amounts of said antibiotic to produce two or more test cultures; and (c) comparing the distribution of TnA insertions between test cultures to identify a putative essential gene serving as a target of said antibiotic in said bacterium.Type: ApplicationFiled: November 4, 2013Publication date: May 22, 2014Applicant: DISCUVA LIMITEDInventors: DAVID HUGH WILLIAMS, Arthur Keith Turner
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Publication number: 20140135234Abstract: Disclosed is a method for identifying an essential gene which serves as an antibiotic target in a bacterium, the method comprising the steps of: (a) generating an antibiotic resistant mutant of said bacterium by a method comprising the step of selecting for growth in the presence of said antibiotic to produce an antibiotic resistant mutant clone (AbR mutant); (b) transforming the AbR mutant with: (i) one or more essential genes of said bacterium; and (ii) a transposon which insertionally inactivates bacterial DNA, to produce a pool of transposon mutants which are merodiploid for said one or more essential genes; (c) growing bacteria from the merodiploid pool in the presence of different amounts of said antibiotic to produce two or more test cultures; and (d) comparing the distribution of transposon insertions between test cultures to identify a putative essential gene serving as a target of said antibiotic in said bacterium.Type: ApplicationFiled: November 4, 2013Publication date: May 15, 2014Applicant: DISCUVA LIMITEDInventors: DAVID HUGH WILLIAMS, Arthur Keith Turner
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Patent number: 8597285Abstract: A cryoprobe for use in cryosurgery and other applications comprising a rigid outer tube, an inner coolant inlet tube. a short rigid penetrating segment extending distally from the distal end of the outer tube and a helical-shaped baffle having a heating element disposed about the outer surface of the inlet tube. The baffle is adapted to produce turbulent fluid flow improving heat transfer and is able to warm target tissue during rapid freezing and thawing cycles.Type: GrantFiled: November 9, 2010Date of Patent: December 3, 2013Assignee: Sanarus Technologies, LLCInventors: Russell L. DeLonzor, James B. Ross, Mathew J. Nalipinski, Keith Turner, David J. Foster, Tom A. Oakley, Michael R. Cane
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Patent number: 8454824Abstract: A separation process for separating two or more immiscible liquids using contactors utilizing high surface area vertical hanging fibers is disclosed. This separation process is especially useful in the separation of disulfide oil formed during the oxidation of spent caustic solution that was used to remove sulfur contaminates from light hydrocarbons.Type: GrantFiled: October 9, 2012Date of Patent: June 4, 2013Assignee: Merichem CompanyInventors: Tiejun Zhang, V. Keith Turner
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Patent number: 8318148Abstract: The invention provides strains of bacteria, especially enterotoxigenic E. coli, attenuated by mutations in the genes encoding enterotoxins (LT, ST, EAST1) and optionally further attenuated by deletion of additional chromosomal genes. In addition the invention provides strains of attenuated bacteria expressing immunogenic but non-toxic variants of one or more of these enterotoxins. These bacteria are useful as a vaccine against diarrhoeal disease.Type: GrantFiled: March 28, 2011Date of Patent: November 27, 2012Assignee: Acambis Research LimitedInventors: Arthur Keith Turner, Judith Greenwood, Jonathan Clive Stephens, Juliet Claire Beavis, Michael James Darsley
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Patent number: 8308957Abstract: A separation process for separating two or more immiscible liquids using contactors utilizing high surface area vertical hanging fibers is disclosed. This separation process is especially useful in the separation of disulfide oil formed during the oxidation of spent caustic solution that was used to remove sulfur contaminates from light hydrocarbons.Type: GrantFiled: August 3, 2010Date of Patent: November 13, 2012Assignee: Merichem CompanyInventors: Tiejun Zhang, V. Keith Turner
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Publication number: 20110200638Abstract: A bacterial cell which expresses three or more coli surface (CS) antigens and methods of making such a cell. The cell is useful in making vaccines against diarrhea.Type: ApplicationFiled: April 7, 2011Publication date: August 18, 2011Applicant: ACAMBIS RESEARCH LIMITEDInventors: Arthur Keith Turner, Judith Greenwood, Jonathan Clive Stephens, Juliet Claire Beavis, Michael James Darsley
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Publication number: 20110189225Abstract: The invention provides strains of bacteria, especially enterotoxigenic E. coli, attenuated by mutations in the genes encoding enterotoxins (LT, ST, EAST1) and optionally further attenuated by deletion of additional chromosomal genes. In addition the invention provides strains of attenuated bacteria expressing immunogenic but non-toxic variants of one or more of these enterotoxins. These bacteria are useful as a vaccine against diarrhoeal disease.Type: ApplicationFiled: March 28, 2011Publication date: August 4, 2011Applicant: ACAMBIS RESEARCH LIMITEDInventors: ARTHUR KEITH TURNER, JUDITH GREENWOOD, JONATHAN CLIVE STEPHENS, JULIET CLAIRE BEAVIS, MICHAEL JAMES DARSLEY
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Publication number: 20110163008Abstract: In a catalytic treatment process, mercaptans in sour hydrocarbon are oxidized to disulfide oils using an aqueous treatment solution containing a chelated polyvalent metal catalyst, alkali metal hydroxide, and the alkali metal salt of at least one alcohol in a non-dispersive mixing apparatus wherein an upgraded hydrocarbon containing the disulfide oils is produced.Type: ApplicationFiled: January 31, 2011Publication date: July 7, 2011Applicant: MERICHEM COMPANYInventors: Tiejun Zhang, K. Michael Hardy, V. Keith Turner, Ignacio C. Bincaz, Tom Varadi
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Publication number: 20110127194Abstract: In a catalytic treatment process, mercaptans in sour hydrocarbon are oxidized to disulfide oils using an aqueous treatment solution containing a chelated polyvalent metal catalyst, alkali metal hydroxide, and the alkali metal salt of at least one alcohol in a non-dispersive mixing apparatus wherein an upgraded hydrocarbon containing the disulfide oils is produced.Type: ApplicationFiled: November 30, 2009Publication date: June 2, 2011Inventors: Tiejun Zhang, K. Michael Hardy, V. Keith Turner, Ignacio C. Bincaz, Tom Varadi