Patents by Inventor Keith W. Woods

Keith W. Woods has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • New Chemical Entities To Be Used For Wee1 Inhibition For The Treatment Of Cancer
    Publication number: 20130018045
    Abstract: The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, wherein R1, R2, R3, A, B, and n are defined in the description. The present invention relates also to compositions containing said compounds which are useful for inhibiting kinases such as wee-1 and methods of treating diseases such as cancer.
    Type: Application
    Filed: July 12, 2012
    Publication date: January 17, 2013
    Applicant: ABBOTT LABORATORIES
    Inventors: Keith W. Woods, Chunqui Lai, Thomas D. Penning, Julie M. Miyashiro
  • TRICYCLIC INHIBITORS OF KINASES
    Publication number: 20120220572
    Abstract: The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, wherein X, Y, Z, R3 and R4 are defined in the description. The present invention relates also to compositions containing said compounds which are useful for inhibiting kinases such as wee-1 and methods of treating diseases such as cancer.
    Type: Application
    Filed: February 28, 2012
    Publication date: August 30, 2012
    Applicant: ABBOTT LABORATORIES
    Inventors: Yunsong Tong, Thomas D. Penning, Alan S. Florjancic, Julie Miyashiro, Keith W. Woods
  • PYRROLOPYRIDINE INHIBITORS OF KINASES
    Publication number: 20110257152
    Abstract: The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, wherein R1a, R1b, R1c, X, and Y are defined in the description. The present invention relates also to compositions containing said compounds which are useful for inhibiting kinases such as Cdc7 and methods of treating diseases such as cancer.
    Type: Application
    Filed: April 14, 2011
    Publication date: October 20, 2011
    Applicant: ABBOTT LABORATORIES
    Inventors: Thomas D. Penning, Keith W. Woods, Chunqiu Lai, Yunsong Tong, Alan S. Florjancic
  • Cyclobut-3-ene-1,2,-dione inhibitors of polo-like kinases
    Patent number: 7956185
    Abstract: Compounds of formula (I) where X1, C1, and D1 are defined herein, are inhibitors of polo-like kinases. The compounds of formula (I) are useful for treatment of diseases of cellular proliferation, such as, for example, cancer.
    Type: Grant
    Filed: May 24, 2007
    Date of Patent: June 7, 2011
    Assignee: Abbott Laboratories
    Inventors: Robert B. Diebold, Stevan W. Djuric, Vincent L. Giranda, Laura A. Hexamer, Nan-Horng Lin, Julie M. Miyashiro, Thomas D. Penning, Magdalena Przytulinska, Thomas J. Sowin, Gerard M. Sullivan, Zhi-Fu Tao, Yunsong Tong, Anil Vasudevan, Le Wang, Keith W. Woods, Zhiren Xia, Henry Q. Zhang
  • PYRROLOPYRAZINE INHIBITORS OF KINASES
    Publication number: 20110015172
    Abstract: The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, wherein R1a, R1b, X, and Y are defined in the description. The present invention relates also to compositions containing said compounds which are useful for inhibiting kinases such as Cdc7 and methods of treating diseases such as cancer.
    Type: Application
    Filed: July 15, 2010
    Publication date: January 20, 2011
    Applicant: ABBOTT LABORATORIES
    Inventors: Thomas D. Penning, Virajkumar B. Gandhi, Gui-Dong Zhu, Yunsong Tong, Keith W. Woods, Chunqiu Lai, Jane Gong, Alan S. Florjancic
  • Pyrroloquinoxalinone inhibitors of poly(ADP-ribose)polymerase
    Patent number: 7790721
    Abstract: Compounds of formula I where X is a bond; A1 and A2, together with the atoms to which they are attached, is pyrrole; and A3 and A4, together with the atoms to which they are attached, are benzene; are poly(ADP-ribose)polymerase inhibitors. The compounds of formula I are useful for the treatment of diseases such as cancer.
    Type: Grant
    Filed: December 27, 2007
    Date of Patent: September 7, 2010
    Assignee: Abbott Laboratories
    Inventors: Vincent L. Giranda, Julie M Miyashiro, Thomas D Penning, Keith W. Woods
  • 5-SUBSTITUTED INDAZOLES AS KINASE INHIBITORS
    Publication number: 20090203690
    Abstract: The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, wherein A, R1, R2, R3 and m, are defined in the description. The present invention relates also to methods of making said compounds, and compositions containing said compounds which are useful for inhibiting kinases such as Glycogen Synthase kinase 3 (GSK-3), Rho kinase (ROCK), Janus Kinases (JAK), Cdc7, AKT, PAK4, PLK, CK2, KDR, MK2, JNK1, aurora, pim 1 and nek 2.
    Type: Application
    Filed: December 4, 2008
    Publication date: August 13, 2009
    Applicant: ABBOTT LABORATORIES
    Inventors: Irini Akritopoulou-Zanze, Brian D. Wakefield, Helmut Mack, Sean C. Turner, Alan F. Gasiecki, Vijaya J. Gracias, Kathy A. Sarris, Douglas M. Kalvin, Melissa J. Michmerhuizen, Qi Shuai, Jyoti R. Patel, Margaretha H.M. Bakker, Nicole Teusch, Eric F. Johnson, Peter J. Kovar, Stevan W. Djuric, Andrew J. Long, Anil Vasudevan, Dawn George, Lu Wang, Biqin Li, N. St. John Moore, Adrian D. Hobson, Keith W. Woods, Julie M. Miyashiro, Steven L. Swann, JR., Thomas D. Penning
  • INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE
    Publication number: 20080161292
    Abstract: Inhibitors of poly(ADP-ribose)polymerase, ways to make them and methods of treating patients using them are disclosed.
    Type: Application
    Filed: December 27, 2007
    Publication date: July 3, 2008
    Applicant: Abbott Laboratories
    Inventors: Vincent L. Giranda, Julie M. Miyashiro, Thomas D. Penning, Keith W. Woods
  • Cell proliferation inhibitors
    Patent number: 6924304
    Abstract: Compounds having formula (I) inhibit cellular proliferation. Processes for the preparation of the compounds, pharmaceutical compositions containing the compounds, and methods of treatment using the compounds are disclosed.
    Type: Grant
    Filed: November 21, 2002
    Date of Patent: August 2, 2005
    Assignee: Abbott Laboratories
    Inventors: Qun Li, Hing Sham, Keith W. Woods, Beth A. Steiner, Stephen L. Gwaltney, II, Kenneth J. Barr, Hovis M. Imade, Saul Rosenberg
  • Kinase inhibitors
    Patent number: 6831175
    Abstract: Compounds having the formula are useful for inhibiting protein kinases. Also disclosed are compositions which inhibit protein kinases and methods of inhibiting protein kinases in a patient.
    Type: Grant
    Filed: December 12, 2002
    Date of Patent: December 14, 2004
    Assignee: Abbott Laboratories
    Inventors: Qun Li, Keith W. Woods, Gui-Dong Zhu, John P. Fischer, Jianchun Gong, Tongmei Li, Virajkumar Gandhi, Sheela A. Thomas, Garrick K. Packard, Xiaohong Song, Jason N. Abrams, Robert B. Diebold, Jürgen Dinges, Charles W. Hutchins, Vincent S. Stoll, Saul H. Rosenberg, Vincent L. Giranda
  • Farnesyltransferase inhibitors
    Publication number: 20030199542
    Abstract: Compounds having the formula 1
    Type: Application
    Filed: April 18, 2002
    Publication date: October 23, 2003
    Inventors: Keith W. Woods, Qun Li, Hing L. Sham
  • Kinase inhibitors
    Publication number: 20030199511
    Abstract: Compounds having the formula 1
    Type: Application
    Filed: December 12, 2002
    Publication date: October 23, 2003
    Inventors: Qun Li, Keith W. Woods, Gui-Dong Zhu, John P. Fischer, Jianchun Gong, Tongmei Li, Virajkumar Gandhi, Sheela A. Thomas, Garrick K. Packard, Xiaohong Song, Jason N. Abrams, Robert B. Diebold, Jurgen Dinges, Charles W. Hutchins, Vincent S. Stoll, Saul H. Rosenberg, Vincent L. Giranda
  • Farnesyltransferase inhibitors
    Publication number: 20030199544
    Abstract: Compounds having the formula 1
    Type: Application
    Filed: April 18, 2003
    Publication date: October 23, 2003
    Inventors: Keith W. Woods, Qun Li, Hing L. Sham
  • Kinase inhibitors
    Publication number: 20030187026
    Abstract: Compounds having the formula 1
    Type: Application
    Filed: November 18, 2002
    Publication date: October 2, 2003
    Inventors: Qun Li, Keith W. Woods, Gui-Dong Zhu, John P. Fischer, Jianchun Gong, Tongmei Li, Virajkumar Gandhi, Sheela A. Thomas, Garrick K. Packard, Xiaohong Song, Jason N. Abrams, Robert Diebold, Jurgen Dinges, Charles Hutchins, Vincent S. Stoll, Saul H. Rosenberg, Vincent L. Giranda
  • Cell proliferation inhibitors
    Publication number: 20030096856
    Abstract: Compounds having formula (I) 1
    Type: Application
    Filed: November 21, 2002
    Publication date: May 22, 2003
    Inventors: Qun Li, Hing Sham, Keith W. Woods, Beth A. Steiner, Stephen L. Gwaltney, Kenneth J. Barr, Hovis M. Imade, Saul Rosenberg
  • Cell proliferation inhibitors
    Patent number: 6521658
    Abstract: Compounds having formula (I) inhibit cellular proliferation. Processes for the preparation of the compounds, pharmaceutical compositions containing the compounds, and methods of treatment using the compounds are disclosed.
    Type: Grant
    Filed: May 26, 2000
    Date of Patent: February 18, 2003
    Assignee: Abbott Laboratories
    Inventors: Qun Li, Hing Sham, Keith W. Woods, Beth A. Steiner, Stephen L. Gwaltney, II, Kenneth J. Barr, Hovis M. Imade, Saul Rosenberg
  • Triazine angiogenesis inhibitors
    Patent number: 6288228
    Abstract: Compounds having Formula I or pharmaceutically acceptable salts or prodrugs thereof, are useful for treating pathological states which arise from or are exacerbated by angiogenesis. The invention also relates to pharmaceutical compositions comprising these compounds and to methods of inhibiting angiogenesis in a mammal.
    Type: Grant
    Filed: October 5, 2000
    Date of Patent: September 11, 2001
    Assignee: Abbott Laboratories
    Inventors: Jack Henkin, Donald J. Davidson, George S. Sheppard, Keith W. Woods, Richard W. McCroskey
  • Oxazoline antiproliferative agents
    Patent number: 6228868
    Abstract: Compounds having Formula I are useful for treating cancer. Also disclosed are pharmaceutical compositions comprising compounds of Formula I, and methods of treating cancer in a mammal.
    Type: Grant
    Filed: July 23, 1999
    Date of Patent: May 8, 2001
    Assignee: Abbott Laboratories
    Inventors: Stephen L. Gwaltney, II, Hwan-Soo Jae, Douglas M. Kalvin, Gang Liu, Hing L. Sham, Qun Li, Akiyo K. Claiborne, Le Wang, Kenneth J. Barr, Keith W. Woods
  • Imidazole antiproliferative agents
    Patent number: 6201001
    Abstract: Compounds of formula I inhibit celluar proliferation. Processes for the preparation of the compounds, pharmaceutical compositions containing the compounds, and methods of treatment using the compounds are disclosed.
    Type: Grant
    Filed: August 2, 1999
    Date of Patent: March 13, 2001
    Assignee: Abbott Laboratories
    Inventors: Le Wang, Qun Li, Hing L. Sham, Keith W. Woods
  • Heterocyclic compounds as COX-2 inhibitors
    Patent number: 5811425
    Abstract: The present invention relates to COX-2 inhibitors of the formula: ##STR1## wherein, A=halogen, C.sub.1 -C.sub.6 alkyl, SR.sup.1 or OR.sup.1 ;B=O, or H,H;X=Br or Cl;L=5-,6- or 7-membered heteroatom containing rings and is preferrably a 5-membered heteroaromatics such as thiazole, oxazole, imidazole, or oxadiazole;n=1-6, wherein the (C) is optionally branched;R=optionally substituted aryl wherein aryl is selected from phenyl, pyridyl, naphthyl, benzothienyl, or quinoxolyl, alkyl, carboxyl, esters, amino, amide, or urea; andR.sup.1 =alkyl. The compounds are useful as research tools and could be useful as potential therapeutic agents in the inhibition of the PGHS-2 isozyme and in the treatment of inflammation in mammals including humans or other conditions associated with the production of prostaglandins.
    Type: Grant
    Filed: March 4, 1997
    Date of Patent: September 22, 1998
    Assignee: Abbott Laboratories
    Inventors: Keith W. Woods, Richard W. McCroskey, Michael R. Michaelides