Patents by Inventor Keith Washco

Keith Washco has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions comprising amphotericin B, mehods and systems
    Patent number: 8513204
    Abstract: The present invention comprises compositions and formulations comprising amphotericin B, compositions and formulations comprising amphotericin B with one or more excipients, methods of making amphotericin B compositions and formulations, as well as systems for using amphotericin B compositions and formulations. Also provided are pharmaceutical compositions comprising the formulation, methods of administering the pharmaceutical compositions and methods of treating patients with the pharmaceutical compositions.
    Type: Grant
    Filed: September 20, 2006
    Date of Patent: August 20, 2013
    Assignee: Novartis AG
    Inventors: Richard Malcolmson, Alan Kugler, Theresa D. Sweeney, Keith Washco, Danforth Miller
  • Compositions Comprising Amphotericin B
    Publication number: 20120128728
    Abstract: The present invention comprises compositions and formulations comprising amphotericin B comprising less than 10% degradants, compositions and formulations comprising amphotericin B with one or more excipients, methods of making amphotericin B compositions and formulations, as well as systems for using amphotericin B compositions and formulations. Also provided are pharmaceutical compositions comprising the formulation, methods of administering the pharmaceutical compositions and methods of treating patients with the pharmaceutical compositions.
    Type: Application
    Filed: December 21, 2006
    Publication date: May 24, 2012
    Applicant: NOVARTIS PHARMA AG
    Inventors: Richard J. Malcolmson, Theresa D. Sweeney, Danforth P. Miller, Alan R. Kugler, Keith Washco, David Han, Ramakrishna Gadiraju, Farzaneh Nakhjiri
  • Compositions comprising amphotericin B, methods, and systems
    Patent number: 7326691
    Abstract: A composition includes particles including at least about 95 wt % of amphotericin B, wherein the particles have a mass median diameter ranging from about 1.1 ?m to about 1.9 ?m. Another composition also includes particles including at least about 95 wt % of amphotericin B, wherein at least about 80 wt % of the particles have a geometric diameter ranging from about 1.1 ?m to about 1.9 ?m. Yet another composition includes particles including amphotericin B, wherein the particles have a mass median diameter less than about 1.9 ?m, and wherein the amphotericin B has a crystallinity level of at least about 20%. Unit dosage forms, delivery systems, and methods may involve similar compositions.
    Type: Grant
    Filed: June 21, 2005
    Date of Patent: February 5, 2008
    Assignee: Nektar Therapeutics
    Inventors: Sarma Duddu, Srinivas Palakodaty, David Lechuga-Ballesteros, Danforth Miller, Alan R. Kugler, Christopher Frantz, Trixie Tan, Richard Malcolmson, Keith Washco, Theresa Sweeney, Thomas E. Tarara, Sarvajna Dwivedi, Michael A. Eldon
  • Compositions comprising amphotericin B, methods, and systems
    Publication number: 20070123477
    Abstract: The present invention comprises compositions and formulations comprising amphotericin B, compositions and formulations comprising amphotericin B with one or more excipients, methods of making amphotericin B compositions and formulations, as well as systems for using amphotericin B compositions and formulations. Also provided are pharmaceutical compositions comprising the formulation, methods of administering the pharmaceutical compositions and methods of treating patients with the pharmaceutical compositions.
    Type: Application
    Filed: September 20, 2006
    Publication date: May 31, 2007
    Inventors: Richard Malcolmson, Alan Kugler, Theresa Sweeney, Keith Washco, Danforth Miller
  • Compositions comprising amphotericin B, methods, and systems
    Publication number: 20060025355
    Abstract: A composition includes particles including at least about 95 wt % of amphotericin B, wherein the particles have a mass median diameter ranging from about 1.1 ?m to about 1.9 ?m. Another composition also includes particles including at least about 95 wt % of amphotericin B, wherein at least about 80 wt % of the particles have a geometric diameter ranging from about 1.1 ?m to about 1.9 ?m. Yet another composition includes particles including amphotericin B, wherein the particles have a mass median diameter less than about 1.9 ?m, and wherein the amphotericin B has a crystallinity level of at least about 20%. Unit dosage forms, delivery systems, and methods may involve similar compositions.
    Type: Application
    Filed: June 21, 2005
    Publication date: February 2, 2006
    Applicant: Nektar Therapeutics
    Inventors: Sarma Duddu, Srinivas Palakodaty, David Lechuga-Ballesteros, Danforth Miller, Alan Kugler, Christopher Frantz, Trixie Tan, Richard Malcomson, Keith Washco, Theresa Sweeney, Thomas Tarara, Sarvajna Dwivedi, Michael Eldon
  • Gel delivery vehicles for anticellular proliferative agents
    Publication number: 20040076679
    Abstract: Methods and compositions are provided for the treatment of a host suffering from a cellular proliferative disease. In the subject methods, antiproliferative agents are administered in a substantially non-aqueous gel delivery vehicle comprising at least one polar organic solvent in combination with one or more thickening agents. The subject methods and compositions provide for the enhanced efficacy of regionally or locally administered antiproliferative proliferative agents.
    Type: Application
    Filed: September 3, 2003
    Publication date: April 22, 2004
    Inventors: Richard E. Jones, Keith Washco, Kathleen V. Roskos, Richard Maskiewicz, George Trager
  • Gel delivery vehicles for anticellular proliferative agents
    Patent number: 6630168
    Abstract: Methods and compositions are provided for the treatment of a host suffering from a cellular proliferative disease. In the subject methods, antiproliferative agents are administered in a substantially non-aqueous gel delivery vehicle comprising at least one polar organic solvent in combination with one or more thickening agents. The subject methods and compositions provide for the enhanced efficacy of regionally or locally administered antiproliferative proliferative agents.
    Type: Grant
    Filed: February 20, 1997
    Date of Patent: October 7, 2003
    Assignee: BioMedicines, Inc.
    Inventors: Richard E. Jones, Keith Washco, Kathleen V. Roskos, Richard Maskiewicz, George Trager