Abstract: A method and system (1) for incorporating legacy systems in a service oriented architecture (SOA) includes decoupling legacy system business services from legacy system data services by creating, from the legacy system business services and data services, a set of (e.g. Java WebSphere®) SOA business services (5a-5c) for transactions and (e.g. DB2) stored procedures (7a-7d) for SOA data services. The business services are constructed from one or more data services and the transactional integrity of the transaction is maintained, in use. The stored procedures may be written to a transaction log and a check made to verify that all of the stored procedures from which the business service is constructed have been written to the log.

Abstract: Films containing a sealant layer composition comprising: (1) polyethylene homopolymer, and ethylene/alpha-olefin copolymer, ethylene vinyl acetate copolymer, and ethylene/acrylate copolymer; and (2) elastomer, plastomer, ionomer, and carboxyl-modified polyethylene; when sealed to another outer film layer comprising at least one member selected from the group consisting of ionomer, ethylene/acid copolymer, ethylene/vinyl acetate copolymer and ethylene/acrylate copolymer, have been discovered to provide a seal strength comparable to an ionomer to ionomer seal.

Abstract: This invention relates to compounds of formula I their salts, and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions comprising these compounds and their use in the treatment of picornavirus infections in mammals, as well as novel intermediates useful in the preparation of the compounds of formula I.

Abstract: This invention relates to compounds of formula I their salts, and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions comprising these compounds and their use in the treatment of picornavirus infections in mammals, as well as novel intermediates useful in the preparation of the compounds of formula I.

Abstract: The invention relates to compounds of general formula (I); in which R is an amino or guanidino group; R2 is acetyl or trifluoroacetyl; and n is an integer from 10 to 18 or a pharmaceutically acceptable derivative thereof, methods for their preparation, pharmaceutical formulations containing them or their use in the prevention or treatment of a viral infection.

Abstract: Nano-scale DMC catalyst complexes are highly active alkylene oxide polymerization catalysts. Thy show a greatly improved ability to catalyze the formation of EO-capping onto secondary hydroxyl-terminated polyethers. The catalysts can be prepared by precipitation in the dispersed adequous phase of a water-in-oil emulsion.

Abstract: This invention relates to compounds of formula I their salts, and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions comprising these compounds and their use in the treatment of picornavirus infections in mammals, as well as novel intermediates useful in the preparation of the compounds of formula I.

Abstract: This invention relates to compounds of formula I their salts, and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions comprising these compounds and their use in the treatment of picornavirus infections in mammals, as well as novel intermediates useful in the preparation of the compounds of formula I.

Abstract: The present invention relates to novel tyrosine kinase (TK) inhibitors in the form of prodrugs.

Abstract: The invention relates to a multimeric compound or a pharmaceutically acceptable salt or derivative thereof which comprises three or more neuraminidase-binding groups attached to a spacer or linking group, in which the neuraminidase-binding group is a compound which binds to the active site of influenza virus neuraminidase, but is not cleaved by the neuraminidase. The invention also relates to processes for the preparation of the multimeric compound defined above, pharmaceutical compositions containing them or methods for the treatment and/or prophylaxis of a viral infection involving them.

Abstract: This invention relates to compounds of formula I their salts, and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions comprising these compounds and their use in the treatment of picornavirus infections in mammals as well as novel intermediates useful in the preparation of the compounds of formula I

Abstract: Disclosed herein are compounds of formula II: wherein Alk, Z, X1, X2, R1, —R10 and R11 are defined herein, and their salts and pharmaceutically acceptable derivatives thereof, as well as other compounds of the general formula Het-A-Alk-W-Ar-C(X2)?NO-X2 where Het, A, W and Ar are also defined herein. These compounds are useful in treating picornavirus infections in mammals. Novel intermediates of these compounds, as well as pharmaceutical compositions and methods of use, are also disclosed herein.

Abstract: Films containing a sealant layer composition comprising: (1) polyethylene homopolymer, and ethylene/alpha-olefin copolymer, ethylene vinyl acetate copolymer, and ethylene/acrylate copolymer; and (2) elastomer, plastomer, ionomer, and carboxyl-modified polyethylene; when sealed to another outer film layer comprising at least one member selected from the group consisting of ionomer, ethylene/acid copolymer, ethylene/vinyl acetate copolymer and ethylene/acrylate copolymer, have been discovered to provide a seal strength comparable to an ionomer to ionomer seal.

Abstract: A method, system and graphic user interface for modifying a recipient field label associated with a recipient of an e-mail message are disclosed. A recipient field label modifier function is provided that operates to modify the recipient field label associated with a selected recipient. An object associated with the modifier function is provided on a screen including a list of e-mail recipients. Selection of the object associated with the modifier function causes objects to be displayed for modifying the recipient field label associated with a selected recipient to any available type of recipient field label.

Abstract: Cyclic oligomers containing ester linkages are polymerized in the presence of a catalyst having at least one oxygen atom bonded to two metal atoms. At least one of the metal atoms is a tin atom, which is preferably tetravalent, i.e., bonded to three other groups in addition to the oxygen atom. The other metal atom may also be another tin atom, which is again preferably tetravalent, or a zinc, aluminum or titanium atom. The catalyst may contain multiple oxygen atoms that are bonded to two such metal atoms as described. These catalysts are active, efficient polymerization catalysts. They are often liquids at polymerization temperatures. The catalysts can be formed in situ in the polymerization process, which provides additional flexibility in the process and increased storage stability of starting materials.

Abstract: A method for automated design of orthotic and prosthetic devices has been developed. The method includes scanning a three dimensional model of the patient's limb with a laser scanner. The model is loaded into a computer for use in manufacturing an orthotic or prosthetic device. Before the model is used, it is modified by reducing the overall volume of the model by up to twelve percent of the total volume. Also the model's distal end length is reduced by a calculated percentage of the thickness of a prosthetic liner to be worn with the prosthetic device.

Abstract: The invention is a photoswitchable benzocyclobutene-based polymer that while remaining aqueous developable, avoids the problem of significant moisture uptake. The oligomer or polymer comprises a polymeric backbone, benzocyclobutene reactive groups, and photoswitchable pendant groups. The pendant groups are bonded to the polymeric backbone and are characterized by the presence of a moiety that converts to carboxylic acid upon exposure to activating wavelengths of radiation a carboxylic acid. When the oligomer or polymer is subsequently heated to cause cure of the oligomer or polymer, carbon dioxide is emitted and the group forms a substantially non-polar moiety. The invention is also a method of making such a polymer and a method of forming a patterned film using such a polymer.

Abstract: A scent media that uses silicone or other elastomeric material as a base component has been developed. The method for making a scented media, includes forming an elastomeric material and then adding a scented material to the elastomeric material to form the scented media. Finally the scented media is cured for a specified time based on the desired characteristics for the media.

Abstract: The invention relates to compounds of general formula (I); in which R is an amino or guanidino group; R2 is acetyl or trifluoroacetyl; and n is an integer from 10 to 18 or a pharmaceutically acceptable derivative thereof, methods for their preparation, pharmaceutical formulations containing them or their use in the prevention or treatment of a viral infection.