Abstract: This invention relates to chemical polymer compositions, methods of synthesis, and fabrication methods for devices regarding polymers capable of displaying shape memory behavior (SMPs) and which can first be polymerized to a linear or branched polymeric structure, having thermoplastic properties, subsequently processed into a device through processes typical of polymer melts, solutions, and dispersions and then crossed linked to a shape memory thermoset polymer retaining the processed shape.

Abstract: The present invention relates to compositions or vaccines for combating Mycoplasma hyopneumoniae (M hyo), Porcine Circovirus type 2 (PCV2), and Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) infections in animals and for increasing the ability of pigs to gain weight and/or improve death loss, methods of vaccination against the infections, and kits for use with such methods and compositions.

Abstract: Disclosed herein are compounds and compositions having potency in the modulation of Myc family proteins. Such compounds and compositions can be used in the treatment of proliferative diseases, such as cancer, or in the treatment of disease where modulation of Myc family proteins is desired. Also disclosed herein are methods of using said compounds and compositions.

Abstract: The present system for modeling intelligent sensor selection and placement takes signal and sensor information and calculates a statistical inference. As signal data passes through a series of processors, it is transformed by functions to account for signal emission, sensor reception, environmental factors, and noise. This produces a simulation of what the emitted signal would appear to be at a given sensor. The system may be used to select the most effective sensors for a given area or to determine the best sensor coverage for a given area.

Abstract: Methods, systems, and devices supporting data processing are described. In some systems, a data processing platform may support communication message analysis using machine learning. For example, a system may receive a set of communication messages (e.g., social media messages) and perform a machine learning process on the message contents and message interaction data to train a machine learned model. The system may further receive a subject line for a communication message for analysis, input the subject line into the machine learned model, and receive, as an output of the machine learned model, an engagement score based on the subject line. The engagement score may indicate an estimated probability that a user receiving the communication message opens the communication message (e.g., based on the subject line). A user—or the system—may modify the subject line based on the analysis to improve the engagement score.

Abstract: Disclosed herein are compounds and compositions having potency in the modulation of Myc family proteins. Such compounds and compositions can be used in the treatment of proliferative diseases, such as cancer, or in the treatment of disease where modulation of Myc family proteins is desired. Also disclosed herein are methods of using said compounds and compositions.

Abstract: Provided herein are methods of treating acute myeloid leukemia (AML) and multiple myeloma (MM) by administering an effective amount of a cell population comprising natural killer cells, wherein the cell population comprising natural killer cells is produced by a three-stage method comprising culturing a population of hematopoietic stem or progenitor cells in media comprising stem cell mobilizing factors, e.g., three-stage methods of producing NK cells in media comprising stem cell mobilizing factors starting with hematopoietic stem or progenitor cells from cells of the placenta, for example, from placental perfusate (e.g., human placental perfusate) or other tissues, for example, umbilical cord blood or peripheral blood. Further provided herein are methods of using the NK cells produced by the three-stage methods provided herein to suppress the proliferation of acute myeloid leukemia cells.

Abstract: A computing system of an organization receives data through multiple channels of communication; a programmatic interface for each of the different channel infrastructures may be called to convert data about a user's contact with the system. Contact records for contain data such as a user ID and a channel identifier. An operational database may receive the converted contact records from the devices or software. A transaction application may perform various tasks resulting in the generation of transaction data. A transaction record containing the transaction data may be generated in a message queue or operational database. The interface for the communication channel may convert the transaction data in a message queue, after the transaction data is detected by a listening application that monitors the message queue and logs new transaction data to the operational database.

Abstract: A method of upgrading refining streams with high polynucleararomatic hydrocarbon (PNA) concentrations can include: hydrocracking a PNA feed in the presence of a catalyst and hydrogen at 380° C. to 430° C., 2500 psig or greater, and 0.1 hr?1 to 5 hr?1 liquid hourly space velocity (LSHV), wherein the weight ratio of PNA feed to hydrogen is 30:1 to 10:1, wherein the PNA feed comprises 25 wt % or less of hydrocarbons having a boiling point of 700° F. (371° C.) or less and having an aromatic content of 50 wt % or greater to form a product comprising 50 wt % or greater of the hydrocarbons having a boiling point of 700° F. (371° C.) or less and having an aromatic content of 20 wt % or less.

Abstract: Methods, systems, and devices supporting data processing are described. In some systems, a data processing platform may support communication message analysis using machine learning. For example, a system may receive a set of communication messages (e.g., social media messages) and perform a machine learning process on the message contents and message interaction data to train a machine learned model. The system may further receive a subject line for a communication message for analysis, input the subject line into the machine learned model, and receive, as an output of the machine learned model, an engagement score based on the subject line. The engagement score may indicate an estimated probability that a user receiving the communication message opens the communication message (e.g., based on the subject line). A user—or the system—may modify the subject line based on the analysis to improve the engagement score.

Abstract: A method and apparatus for generating a profile page. A computer system identifies a group of potential profiles images from an image. The computer system identifies a group of features in the image. The computer system generates the profile page based on a potential profile image selected from the group of potential profile images and the group of features in the image. The computer system displays the profile page on a display system, enabling generating the profile page.

Abstract: Provided herein are methods of producing natural killer (NK) cells using a three-stage expansion and differentiation method with media comprising stem cell mobilizing factors. Also provided herein are methods of suppressing tumor cell proliferation using the NK cells and the NK cell populations produced by the three-stage methods described herein, as well as methods of treating individuals having cancer or a viral infection, comprising administering the NK cells and the NK cell populations produced by the three-stage methods described herein to an individual having the cancer or viral infection.

Abstract: The present disclosure provides processes for hydroprocessing hydrocarbon feedstocks comprising a silicon content of about 1 wppm or greater. In at least one embodiment, a process includes introducing, in a reactor or to the reactor, a hydrocarbon feedstock having a silicon content of at least about 1 wppm, based on the total weight of the hydrocarbon feedstock, to a treat gas to produce a hydrocarbon feedstock/treat gas mixture. The process includes introducing the hydrocarbon feedstock/treat gas mixture to a catalyst composition comprising at least one group 6 metal and at least one group 8-10 metal, wherein the molar ratio of group 6 metal to group 8-10 metal is from about 10:1 to about 1:10. The process includes obtaining a liquid product comprising a sulfur content of 5,000 wppm or less. Furthermore, processes of the present disclosure provide hydroprocessing of high Si content feeds using hydrocarbon feeds at high liquid hourly space velocities.

Abstract: A method and apparatus for facilitating networking in a social network. A computer system identifies a group of features in an image for a person in the social network. The computer system also identifies a characteristic for networking from the group of features. Further, the computer system identifies a set of people in the social network having the characteristic. The computer system also performs an action enabling networking in the social network with respect to the person and the set of people in the social network having the characteristic.

Abstract: The invention relates to the purification of bispecific antibodies carrying a different specificity for each binding site of the immunoglobulin molecule from a mixture of monospecific antibodies. The bispecific antibodies are composed of a single heavy chain and two different light chains, one containing a Kappa constant domain and the other a Lambda constant domain. This invention in particular relates to the isolation of these bispecific antibodies from mixtures that contain monospecific antibodies having two Kappa light chains or portions thereof and monospecific antibodies having two Lambda light chains or portions thereof. The invention also provides the methods of efficiently purifying these bispecific antibodies.

Abstract: A method of upgrading refining streams with high polynucleararomatic hydrocarbon (PNA) concentrations can include: hydrocracking a PNA feed in the presence of a catalyst and hydrogen at 380° C. to 430° C., 2500 psig or greater, and 0.1 hr?1 to 5 hr?1 liquid hourly space velocity (LSHV), wherein the weight ratio of PNA feed to hydrogen is 30:1 to 10:1, wherein the PNA feed comprises 25 wt % or less of hydrocarbons having a boiling point of 700° F. (371° C.) or less and having an aromatic content of 50 wt % or greater to form a product comprising 50 wt % or greater of the hydrocarbons having a boiling point of 700° F. (371° C.) or less and having an aromatic content of 20 wt % or less.

Abstract: A method and apparatus for providing assistance for an application. The application runs in a web browser displayed on a display system for a client device. The application monitors for user input to the web browser. When assistance is needed for a location in the web page, the location is identified based on the user input. A graphical element with a portion of the web page at the location is generated. A group of audio files on how to use the application at the location is identified. The graphical element with the portion of the web page at the location is displayed on the display system. The audio files are played on the client device while the graphical element with the portion of the web page at the location of the web page is displayed. The audio files and the graphical element provide the assistance.

Abstract: A base station for wireless network uses one or more MIMO channels having subchannels, to communicate with multiple user equipments, and allocates the sub channels to the user equipments. Different subchannels of a given one of the channels can be allocated to different user equipments. The ability to allocate sub channels individually rather than only allocating entire channels can enable higher data rates to be achieved. This is particularly useful for improving data rates at cell boundaries or sector boundaries, where the coverage is traditionally weakest. A user equipment can use subchannels from different MIMO channels from different sectors or from different base stations.

Abstract: The invention relates to the purification of bispecific antibodies carrying a different specificity for each binding site of the immunoglobulin molecule from a mixture of monospecific antibodies. The bispecific antibodies are composed of a single heavy chain and two different light chains, one containing a Kappa constant domain and the other a Lambda constant domain. This invention in particular relates to the isolation of these bispecific antibodies from mixtures that contain monospecific antibodies having two Kappa light chains or portions thereof and monospecific antibodies having two Lambda light chains or portions thereof. The invention also provides the methods of efficiently purifying these bispecific antibodies.

Abstract: A computing system of an organization receives data through multiple channels of communication; a programmatic interface for each of the different channel infrastructures may be called to convert data about a member's contact with the system. Contact records for contain data such as a member ID and a channel identifier. An operational database may receive the converted contact records from the devices or software. A transaction application may perform various tasks resulting in the generation of transaction data. A transaction record containing the transaction data may be generated in a message queue or operational database. The interface for the communication channel may convert the transaction data in a message queue, after the transaction data is detected by a listening application that monitors the message queue and logs new transaction data to the operational database.