Patents by Inventor Keivan SADRERAFI

Keivan SADRERAFI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CYCLODEXTRIN DIMERS AND USES THEREOF
    Publication number: 20240043661
    Abstract: CD dimers, CD compositions, and uses thereof are disclosed herein. CD dimers, and compositions thereof, that may be useful for various purposes including the targeting of 7KC. The design and testing of CD dimers are described herein. Exemplary CD dimers include heterodimers, homodimers, or asymmetric dimer.
    Type: Application
    Filed: July 7, 2021
    Publication date: February 8, 2024
    Inventors: Matthew S. O'Connor, Maria de los Angeles Estiarte-Martinez, Amelia M. Anderson, Daniel M. Clemens, Christine A.T.M.B. Tom, Milo Malanga, Michael Kope, Keivan Sadrerafi
  • Bisphosphonate quinolone conjugates and uses thereof
    Patent number: 11840549
    Abstract: Described herein are bisphosphonate quinolone compounds, conjugates and pharmaceutical formulations thereof that can include a bisphosphonate and a quinolone, where the quinolone can be releasably coupled to the bisphosphonate. Also provided herein are methods of making and methods of using the bisphosphonate quinolone compounds, conjugates and pharmaceutical formulations thereof.
    Type: Grant
    Filed: December 11, 2020
    Date of Patent: December 12, 2023
    Assignees: BIOVINC, LLC, UNIVERSITY OF SOUTHERN CALIFORNIA
    Inventors: Frank H. Ebetino, Shuting Sun, Mark W. Lundy, Charles E. McKenna, Eric Richard, Parish Sedghizadeh, Keivan Sadrerafi, Philip T. Cherian
  • Skeletal removal of bisphosphonates
    Patent number: 11400104
    Abstract: Disclosed herein are methods and compositions for removing or displacing bisphosphonates in skeletal tissue.
    Type: Grant
    Filed: October 29, 2020
    Date of Patent: August 2, 2022
    Assignees: The Regents of the University of California, BioVinc LLC, University of Southern California
    Inventors: Frank Hallock Ebetino, Ichiro Nishimura, Shuting Sun, Mark Walden Lundy, Akishige Hokugo, Charles McKenna, Keivan Sadrerafi
  • CYCLODEXTRIN DIMERS AND USES THEREOF
    Publication number: 20210403607
    Abstract: CD dimers, CD compositions, and uses thereof are disclosed herein.
    Type: Application
    Filed: July 7, 2021
    Publication date: December 30, 2021
    Inventors: Matthew S. O'Connor, Maria de los Angeles Estiarte-Martinez, Amelia M. Anderson, Daniel M. Clemens, Christina A.T.M.B. Tom, Milo Malanga, Michael Kope, Keivan Sadrerafi
  • BONE TARGETED ANTIMICROBIAL OXAZOLIDINONE RELATED COMPOUNDS, FORMULATIONS THEREOF, AND USES THEREOF
    Publication number: 20210369849
    Abstract: Described herein are bisphosphonate oxazolidinone compounds, and conjugates and pharmaceutical formulations thereof, that can include a bisphosphonate and an oxazolidinone (or an oxazolidinone antimicrobial or antibiotic agent, substituent or derivative thereof), where the oxazolidinone can be releasably coupled to the bisphosphonate. Also provided herein are methods of making and methods of using the bisphosphonate oxazolidinone compounds, conjugates and pharmaceutical formulations thereof. Also provided herein are methods of use of the compounds, conjugates and formulations for treating a bone disease or for use in preparing a formulation for the treatment a bone disease.
    Type: Application
    Filed: June 25, 2019
    Publication date: December 2, 2021
    Inventors: Frank Hallock EBETINO, Shuting SUN, Charles E. MCKENNA, Keivan SADRERAFI, Philip CHERIAN
  • Skeletal Removal of Bisphosphonates
    Publication number: 20210121485
    Abstract: Disclosed herein are methods and compositions for removing or displacing bisphosphonates in skeletal tissue.
    Type: Application
    Filed: October 29, 2020
    Publication date: April 29, 2021
    Inventors: Frank Hallock Ebetino, Ichiro Nishimura, Shuting Sun, Mark Walden Lundy, Akishige Hokugo, Charles McKenna, Keivan Sadrerafi
  • BISPHOSPHONATE QUINOLONE CONJUGATES AND USES THEREOF
    Publication number: 20210101920
    Abstract: Described herein are bisphosphonate quinolone compounds, conjugates and pharmaceutical formulations thereof that can include a bisphosphonate and a quinolone, where the quinolone can be releasably coupled to the bisphosphonate. Also provided herein are methods of making and methods of using the bisphosphonate quinolone compounds, conjugates and pharmaceutical formulations thereof.
    Type: Application
    Filed: December 11, 2020
    Publication date: April 8, 2021
    Inventors: Frank H. EBETINO, Shuting SUN, Mark W. LUNDY, Charles E. MCKENNA, Eric RICHARD, Parish SEDGHIZADEH, Keivan SADRERAFI, Philip T. CHERIAN
  • Bisphosphonate quinolone conjugates and uses thereof
    Patent number: 10865220
    Abstract: Described herein are bisphosphonate quinolone compounds, conjugates and pharmaceutical formulations thereof that can include a bisphosphonate and a quinolone, where the quinolone can be releasably coupled to the bisphosphonate. Also provided herein are methods of making and methods of using the bisphosphonate quinolone compounds, conjugates and pharmaceutical formulations thereof.
    Type: Grant
    Filed: December 3, 2018
    Date of Patent: December 15, 2020
    Assignees: BIOVINC, LLC, UNIVERSITY OF SOUTHERN CALIFORNIA
    Inventors: Frank H. Ebetino, Shuting Sun, Mark W. Lundy, Charles E. McKenna, Eric Richard, Parish Sedghizadeh, Keivan Sadrerafi, Philip T. Cherian
  • Skeletal removal of bisphosphonates
    Patent number: 10857165
    Abstract: Disclosed herein are methods and compositions for removing or displacing bisphosphonates in skeletal tissue.
    Type: Grant
    Filed: May 31, 2017
    Date of Patent: December 8, 2020
    Assignees: The Regents of the University of California, BioVinc LLC, University of Southern California
    Inventors: Frank Hallock Ebetino, Ichiro Nishimura, Shuting Sun, Mark Walden Lundy, Akishige Hokugo, Charles McKenna, Keivan Sadrerafi
  • Skeletal Removal of Bisphosphonates
    Publication number: 20190209590
    Abstract: Disclosed herein are methods and compositions for removing or displacing bisphosphonates in skeletal tissue.
    Type: Application
    Filed: May 31, 2017
    Publication date: July 11, 2019
    Inventors: Frank Hallock Ebetino, Ph.D., Ichiro Nishimura, Shuting Sun, Mark Walden Lundy, Akishige Hokugo, Charles McKenna, Keivan Sadrerafi
  • BISPHOSPHONATE QUINOLONE CONJUGATES AND USES THEREOF
    Publication number: 20190169214
    Abstract: Described herein are bisphosphonate quinolone compounds, conjugates and pharmaceutical formulations thereof that can include a bisphosphonate and a quinolone, where the quinolone can be releasably coupled to the bisphosphonate. Also provided herein are methods of making and methods of using the bisphosphonate quinolone compounds, conjugates and pharmaceutical formulations thereof.
    Type: Application
    Filed: December 3, 2018
    Publication date: June 6, 2019
    Inventors: Frank H. EBETINO, Shuting SUN, Mark W. LUNDY, Charles E. MCKENNA, Eric RICHARD, Parish SEDGHIZADEH, Keivan SADRERAFI, Philip T. CHERIAN