Patents by Inventor Keizo Sugimachi

Keizo Sugimachi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20030120428
    Abstract: A method of predicting the effectiveness of radiotherapy for cancer patients. A method of predicting the effectiveness of radiotherapy for cancer patients, which includes the steps of: (a) performing a biopsy to collect cancer cells or cancer tissues from a cancer patient, (b) determining the expression level of hepatoma derived growth factor (HDGF) in the cancer cells or cancer tissues obtained in step (a), and (c) on the basis of the results obtained by the determination in step (b), predicting whether or not a significant treatment effect can be obtained when radiotherapy is carried out on the cancer patient.
    Type: Application
    Filed: July 31, 2002
    Publication date: June 26, 2003
    Applicant: PHARMADESIGN, INC.
    Inventors: Masaki Mori, Keizo Sugimachi, Yoichi Tanaka, Kenji Shibuta, Hiroshi Inoue, Ayumi Matsuyama
  • Patent number: 5141847
    Abstract: In an apparatus which applies periodic pulsation to a solution flowing through a conduit while undergoing perfusion by a pump, a first valve is disposed in the conduit downstream of the pump, a bypass line is provided to the conduit downstream of the first valve, and a second valve is disposed in the bypass line for withdrawing some of a first pulsed flow formed in the conduit by opening and closing the first valve, through the bypass line as a second pulsed flow. A valve driving circuit periodically opens and closes the first valve and second valve at predetermined time schedules so that the second pulsed flow is superimposed upon the first pulsed flow to form a waveform in the conduit. Any desired pulsatile waveform can be obtained by adjusting the pulse width, the crest values, the delay time, etc., of the two pulsed flows.
    Type: Grant
    Filed: February 20, 1990
    Date of Patent: August 25, 1992
    Assignee: Kureha Chemical Industry Co., Ltd.
    Inventors: Keizo Sugimachi, Kenji Takenaka, Mitsuo Shimada, Kengo Fukuzawa, Takashi Nishizaki, Tetsuo Ikeda, Atsushi Yoshihara
  • Patent number: 4676258
    Abstract: A device for radio-frequency hyperthermia havinga first electrode adapted to be disposed in a tract organ of a living body.A second electrode is provided which is adapted to be disposed on an outer circumference of the living body such that the second electrode is opposed to the first electrode such that there is generated a spatially inhomogeneous electric field within the living body in cooperation with the first electrode so that a part of the living body near the first electrode may be heated more strongly than a part of the living body near the second electrode.This serves to selectively heat a tumor or malignancy region at the deep inside of the living body by a noninvasive technique.
    Type: Grant
    Filed: June 5, 1986
    Date of Patent: June 30, 1987
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Kiyoshi Inokuchi, Keizo Sugimachi, Toshiharu Shirakami, Hidenobu Kai, Yoshio Kawai, Tetsuya Hotta
  • Patent number: 4662383
    Abstract: An endotract antenna used for hyperthermia treatments. A microwave radiation antenna is surrounded by a balloon-like member made of a thin polymeric film. Tubes for feeding and draining a cooling liquid to and from the inside of the balloon-like member enable the device to effectively warm an endotract lesion such as a tumor by effectively supplying the energy of the microwaves emitted from the antenna to the endotract lesion.
    Type: Grant
    Filed: September 23, 1983
    Date of Patent: May 5, 1987
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Akira Sogawa, Kiyoshi Inokuchi, Keizo Sugimachi, Hidenobu Kai, Tetsuya Hotta, Yoshio Kawai