Patents by Inventor Kejia Wu
Kejia Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240124426Abstract: Disclosed herein are compounds of Formula (I), or pharmaceutically acceptable salts thereof, that are inhibitors of Polo Like Kinase 4 (PLK4). Also disclosed herein are pharmaceutical compositions comprising the compounds of Formula (I), or pharmaceutically acceptable salts thereof, and one or more pharmaceutically acceptable excipients. Further disclosed herein are methods of treating cancer in a subject in need thereof, comprising administering to the subject an amount of a compound of Formula (I), or a pharmaceutically acceptable salt thereof.Type: ApplicationFiled: August 18, 2023Publication date: April 18, 2024Inventors: Chudi NDUBAKU, Jared Thomas MOORE, Paul Anthony GIBBONS, Jae Hyuk CHANG, F. Anthony ROMERO, Xiaohui DU, Hiroyuki KAWAI, Stephane CIBLAT, Hong WANG, Vincent ALBERT, Lea CONSTANTINEAU-FORGET, Hugo de Almeida SILVA, Dilan Emine POLAT, Amit NAYYAR, Daniel Gordon Michael SHORE, Kejia WU, Joanne TAN
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Publication number: 20240124512Abstract: Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.Type: ApplicationFiled: September 28, 2023Publication date: April 18, 2024Inventors: Xiaohui DU, John EKSTEROWICZ, Valeria R. FANTIN, Daqing SUN, Qiuping YE, Jared MOORE, Tatiana ZAVOROTINSKAYA, Brian R. BLANK, Yosup REW, Kejia WU, Liusheng ZHU, Johnny PHAM, Hiroyuki KAWAI
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Publication number: 20240025906Abstract: The invention provides compounds that modulate the activity of protein kinases that are associated with human diseases, disorders, and conditions. In particular, compounds of the invention inhibit TYK2, a member of the Janus Kinase (JAK) family of non-receptor protein kinases.Type: ApplicationFiled: June 16, 2023Publication date: January 25, 2024Inventors: Zhonghua Pei, Gyanendra Kumar, Anh Truong, Claudio Aquino, Derek Kejia Wu, Andrew Tasker
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Patent number: 11858915Abstract: Disclosed herein are compounds of Formula (I), or pharmaceutically acceptable salts thereof, that are inhibitors of Polo Like Kinase 4 (PLK4). Also disclosed herein are pharmaceutical compositions comprising the compounds of Formula (I), or pharmaceutically acceptable salts thereof, and one or more pharmaceutically acceptable excipients. Further disclosed herein are methods of treating cancer in a subject in need thereof, comprising administering to the subject an amount of a compound of Formula (I), or a pharmaceutically acceptable salt thereof.Type: GrantFiled: April 27, 2023Date of Patent: January 2, 2024Assignee: ORIC PHARMACEUTICALS, INC.Inventors: Chudi Ndubaku, Jared Thomas Moore, Paul Anthony Gibbons, Jae Hyuk Chang, F. Anthony Romero, Xiaohui Du, Hiroyuki Kawai, Stephane Ciblat, Hong Wang, Vincent Albert, Lea Constantineau-Forget, Hugo De Almeida Silva, Dilan Emine Polat, Amit Nayyar, Daniel Gordon Michael Shore, Kejia Wu, Joanne Tan
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Publication number: 20230410848Abstract: This application provides techniques for generating audio and video materials.Type: ApplicationFiled: June 7, 2023Publication date: December 21, 2023Inventors: Kejia WU, Yiou LI, Qiming CHEN, Yiwen YE, Bonan MA, Ligen WANG, Sizhen ZHU, Jingwei LI, Weifa YUAN, Jingwei MA, Maosu HE
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Publication number: 20230365537Abstract: Disclosed herein are compounds of Formula (I), or pharmaceutically acceptable salts thereof, that are inhibitors of Polo Like Kinase 4 (PLK4). Also disclosed herein are pharmaceutical compositions comprising the compounds of Formula (I), or pharmaceutically acceptable salts thereof, and one or more pharmaceutically acceptable excipients. Further disclosed herein are methods of treating cancer in a subject in need thereof, comprising administering to the subject an amount of a compound of Formula (I), or a pharmaceutically acceptable salt thereof.Type: ApplicationFiled: April 27, 2023Publication date: November 16, 2023Inventors: Chudi NDUBAKU, Jared Thomas MOORE, Paul Anthony GIBBONS, Jae Hyuk CHANG, F. Anthony ROMERO, Xiaohui DU, Hiroyuki KAWAI, Stephane CIBLAT, Hong WANG, Vincent ALBERT, Lea CONSTANTINEAU-FORGET, Hugo de Almeida SILVA, Dilan Emine POLAT, Amit NAYYAR, Daniel Gordon Michael SHORE, Kejia WU, Joanne TAN
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Patent number: 11807658Abstract: Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.Type: GrantFiled: March 17, 2022Date of Patent: November 7, 2023Assignee: ORIC PHARMACEUTICALS, INC.Inventors: Xiaohui Du, John Eksterowicz, Valeria R. Fantin, Daqing Sun, Qiuping Ye, Jared Moore, Tatiana Zavorotinskaya, Brian R. Blank, Yosup Rew, Kejia Wu, Liusheng Zhu, Johnny Pham, Hiroyuki Kawai
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Publication number: 20230250134Abstract: Polypeptide inhibitors of SARS-COV-2 are disclosed comprising an amino acid sequence at least 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to the amino acid sequence selected from the group consisting of SEQ ID NOS: 1-17, 19-21, 23-34 and 100-101, and their use for treating and limiting development of SARS-COV-2 infection.Type: ApplicationFiled: May 25, 2021Publication date: August 10, 2023Inventors: Longxing CAO, Brian COVENTRY, Inna GORESHNIK, Lauren MILLER, David BAKER, Lisa KOZODOY, John BOWEN, Lauren CARTER, James Brett CASE, Michael DIAMOND, Natasha EDMAN, Andrew HUNT, Michael Christopher JEWETT, Cassandra Jean OGOHARA, Young-jun PARK, Rashmi RAVICHANDRAN, Lance Joseph STEWART, David VEESLER, Bastian VOGELI, Alexandra C. WALLS, Kejia WU, Scott BOYKEN, George UEDA
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Publication number: 20230131747Abstract: Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.Type: ApplicationFiled: October 31, 2022Publication date: April 27, 2023Inventors: Xiaohui DU, John EKSTEROWICZ, Valeria R. FANTIN, Daqing SUN, Qiuping YE, Jared MOORE, Tatiana ZAVOROTINSKAYA, Brian R. BLANK, Yosup REW, Kejia WU, Liusheng ZHU, Johnny PHAM, Hiroyuki KAWAI, Chien-Hung YEH
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Publication number: 20220411459Abstract: Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.Type: ApplicationFiled: October 29, 2020Publication date: December 29, 2022Inventors: Xiaohui DU, John EKSTEROWICZ, Valeria R. FANTIN, Daqing SUN, Qiuping YE, Jared MOORE, Tatiana ZAVOROTINSKAYA, Brian R. BLANK, Yosup REW, Kejia WU, Liusheng ZHU, Johnny PHAM, Hiroyuki KAWAI, Chien-Hung YEH
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Patent number: 11530236Abstract: Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.Type: GrantFiled: October 29, 2020Date of Patent: December 20, 2022Assignee: ORIC PHARMACEUTICALS, INC.Inventors: Xiaohui Du, John Eksterowicz, Valeria R. Fantin, Daqing Sun, Qiuping Ye, Jared Moore, Tatiana Zavorotinskaya, Brian R. Blank, Yosup Rew, Kejia Wu, Liusheng Zhu, Johnny Pham, Hiroyuki Kawai, Chien-Hung Yeh
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Publication number: 20220331343Abstract: Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.Type: ApplicationFiled: July 15, 2020Publication date: October 20, 2022Inventors: Xiaohui DU, John EKSTEROWICZ, Valeria R. FANTIN, Daqing SUN, Qiuping YE, Jared MOORE, Tatiana ZAVOROTINSKAYA, Brian R. BLANK, Hiroyuki KAWAI, Chien-Hung YEH, Yosup REW, Kejia WU, Johnny PHAM
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Publication number: 20220220147Abstract: Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.Type: ApplicationFiled: March 17, 2022Publication date: July 14, 2022Inventors: Xiaohui DU, John EKSTEROWICZ, Valeria R. FANTIN, Daqing SUN, Qiuping YE, Jared MOORE, Tatiana ZAVOROTINSKAYA, Brian R. BLANK, Yosup REW, Kejia WU, Liusheng ZHU, Johnny PHAM, Hiroyuki KAWAI
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Patent number: 11325938Abstract: Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.Type: GrantFiled: October 23, 2020Date of Patent: May 10, 2022Assignee: ORIC PHARMACEUTICALS, INC.Inventors: Xiaohui Du, John Eksterowicz, Valeria R. Fantin, Daqing Sun, Qiuping Ye, Jared Moore, Tatiana Zavorotinskaya, Brian R. Blank, Yosup Rew, Kejia Wu, Liusheng Zhu, Johnny Pham, Hiroyuki Kawai
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Publication number: 20220079924Abstract: Described herein are glucocorticoid receptor modulators and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer and hypercortisolism.Type: ApplicationFiled: October 9, 2019Publication date: March 17, 2022Inventors: Xiaohui DU, John EKSTEROWICZ, Valeria R. FANTIN, Yosup REW, Daqing SUN, Qiuping YE, Haiying ZHOU, Hiroyuki KAWAI, Jared MOORE, Johnny PHAM, Kejia WU, Liusheng ZHU
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Patent number: 11130778Abstract: Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.Type: GrantFiled: March 17, 2021Date of Patent: September 28, 2021Assignee: ORIC PHARMACEUTICALS, INC.Inventors: Xiaohui Du, John Eksterowicz, Valeria R. Fantin, Daqing Sun, Qiuping Ye, Jared Moore, Tatiana Zavorotinskaya, Brian R. Blank, Yosup Rew, Kejia Wu, Liusheng Zhu, Johnny Pham, Hiroyuki Kawai, Chien-Hung Yeh
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Publication number: 20210214387Abstract: Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.Type: ApplicationFiled: March 17, 2021Publication date: July 15, 2021Inventors: Xiaohui DU, John EKSTEROWICZ, Valeria R. FANTIN, Daqing SUN, Qiuping YE, Jared MOORE, Tatiana ZAVOROTINSKAYA, Brian R. BLANK, Yosup REW, Kejia WU, Liusheng ZHU, Johnny PHAM, Hiroyuki KAWAI, Chien-Hung YEH
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Patent number: 11028120Abstract: Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.Type: GrantFiled: December 8, 2020Date of Patent: June 8, 2021Assignee: ORIC PHARMACEUTICALS, INC.Inventors: Xiaohui Du, John Eksterowicz, Valeria R. Fantin, Daqing Sun, Qiuping Ye, Jared Moore, Tatiana Zavorotinskaya, Brian R. Blank, Yosup Rew, Kejia Wu, Liusheng Zhu, Johnny Pham, Hiroyuki Kawai, Chien-Hung Yeh
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Publication number: 20210130389Abstract: Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.Type: ApplicationFiled: October 29, 2020Publication date: May 6, 2021Inventors: Xiaohui DU, John EKSTEROWICZ, Valeria R. FANTIN, Daqing SUN, Qiuping YE, Jared MOORE, Tatiana ZAVOROTINSKAYA, Brian R. BLANK, Yosup REW, Kejia WU, Liusheng ZHU, Johnny PHAM, Hiroyuki KAWAI, Chien-Hung YEH
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Publication number: 20210130390Abstract: Described herein are CD73 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of cancer, infections, and neurodegenerative diseases.Type: ApplicationFiled: December 8, 2020Publication date: May 6, 2021Inventors: Xiaohui DU, John EKSTEROWICZ, Valeria R. FANTIN, Daqing SUN, Qiuping YE, Jared MOORE, Tatiana ZAVOROTINSKAYA, Brian R. BLANK, Yosup REW, Kejia WU, Liusheng ZHU, Johnny PHAM, Hiroyuki KAWAI, Chien-Hung YEH