Patents by Inventor Kejian Yang

Kejian Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11932564
    Abstract: A system for extracting carbon source from sewage sludge in sewer pipes through online organic and inorganic component separation includes an outer system box, where the outer system box is provided therein with a system body; the system body includes a deodorization module, a pre-treatment module, and a cyclone separation module that are sequentially connected from top to bottom; an upper side wall of the cyclone separation module is provided with an oversize residue pressing module; and the pre-treatment module, the cyclone separation module, and the oversize residue pressing module are electrically connected to a control module. The present disclosure achieves online and on-site quick treatment of the sewage sludge in the sewer pipe, and solves common practical problems arising in the existing centralized treatment and disposal method of sewage sludge in the sewer pipe.
    Type: Grant
    Filed: August 8, 2022
    Date of Patent: March 19, 2024
    Assignee: NORTH CHINA MUNICIPAL ENGINEERING DESIGN & RESEARCH INSTITUTE CO., LTD
    Inventors: Yongli Sun, Xingcan Zheng, Pengfeng Li, Min Yang, Kejian Sui
  • Publication number: 20180193448
    Abstract: Methods and kits for immunizing animals (e.g. mammals) against viral antigens, including herpes-simplex virus type 2 are provided. The protective immune response elicited by the methods and kits is characterized by robust humoral, cellular, and mucosal immunity. In particular, a heterologous immunization method comprising a priming DNA vaccine encoding an antigen and a boosting protein vaccine, in which the protein form of the antigen is encapsulated in liposomes is provided. Methods of preventing primary acute, latent and recurrent viral infections, such as that caused by HSV-2 virus, and methods of providing passive protective immunity against a viral pathogen such as HSV-2 virus to a mammal are also disclosed.
    Type: Application
    Filed: August 11, 2017
    Publication date: July 12, 2018
    Inventors: Kejian YANG, Dennis L. GUBERSKI
  • Publication number: 20180008695
    Abstract: The invention provides methods and kits for inducing a therapeutic immunity in animals (e.g. mammals) against viral antigens, including herpes-simplex virus type 2. In particular, the invention provides a method of treating animals with an established HSV-2 infection by administering a therapeutic vaccine comprising a priming dose of a nucleic acid encoding an HSV-2 antigen, an initial or first boosting dose comprising the protein form of the antigen encapsulated in liposomes, and one or more subsequent boosting doses comprising both the nucleic acid encoding the HSV-2 antigen and the liposomal-encapsulated protein antigen.
    Type: Application
    Filed: September 22, 2017
    Publication date: January 11, 2018
    Inventors: Kejian YANG, Dennis L. GUBERSKI
  • Publication number: 20170258894
    Abstract: The invention provides methods and kits for immunizing animals (e.g. mammals) against viral antigens, including herpes-simplex virus type 2. The protective immune response elicited by the methods and kits of the invention is characterized by robust humoral, cellular, and mucosal immunity. In particular, the invention provides a heterologous immunization method comprising a priming DNA vaccine encoding an antigen and a boosting protein vaccine, in which the protein form of the antigen is encapsulated in liposomes. Methods of preventing primary acute, latent and recurrent viral infections, such as that caused by HSV-2 virus, and methods of providing passive protective immunity against a viral pathogen such as HSV-2 virus to a mammal are also disclosed.
    Type: Application
    Filed: October 21, 2016
    Publication date: September 14, 2017
    Inventors: Kejian YANG, Dennis L. GUBERSKI
  • Patent number: 9566325
    Abstract: The invention provides methods and kits for inducing a therapeutic immunity in animals (e.g. mammals) against viral antigens, including herpes-simplex virus type 2. In particular, the invention provides a method of treating animals with an established HSV-2 infection by administering a therapeutic vaccine comprising a priming dose of a nucleic acid encoding an HSV-2 antigen, an initial or first boosting dose comprising the protein form of the antigen encapsulated in liposomes, and one or more subsequent boosting doses comprising both the nucleic acid encoding the HSV-2 antigen and the liposomal-encapsulated protein antigen.
    Type: Grant
    Filed: January 7, 2014
    Date of Patent: February 14, 2017
    Assignee: BIOMEDICAL RESEARCH MODELS, INC.
    Inventors: Kejian Yang, Dennis L. Guberski
  • Publication number: 20140193483
    Abstract: The invention provides methods and kits for inducing a therapeutic immunity in animals (e.g. mammals) against viral antigens, including herpes-simplex virus type 2. In particular, the invention provides a method of treating animals with an established HSV-2 infection by administering a therapeutic vaccine comprising a priming dose of a nucleic acid encoding an HSV-2 antigen, an initial or first boosting dose comprising the protein form of the antigen encapsulated in liposomes, and one or more subsequent boosting doses comprising both the nucleic acid encoding the HSV-2 antigen and the liposomal-encapsulated protein antigen.
    Type: Application
    Filed: January 7, 2014
    Publication date: July 10, 2014
    Applicant: Biomedical Research Models, Inc.
    Inventors: Kejian YANG, Dennis L. Guberski
  • Publication number: 20130195961
    Abstract: Methods and kits for immunizing animals (e.g. mammals) against viral antigens, including herpes-simplex virus type 2 are provided. The protective immune response elicited by the methods and kits is characterized by robust humoral, cellular, and mucosal immunity. In particular, a heterologous immunization method comprising a priming DNA vaccine encoding an antigen and a boosting protein vaccine, in which the protein form of the antigen is encapsulated in liposomes is provided. Methods of preventing primary acute, latent and recurrent viral infections, such as that caused by HSV-2 virus, and methods of providing passive protective immunity against a viral pathogen such as HSV-2 virus to a mammal are also disclosed.
    Type: Application
    Filed: March 9, 2011
    Publication date: August 1, 2013
    Inventors: Kejian Yang, Dennis I. Guberski
  • Publication number: 20120027841
    Abstract: The invention provides methods and kits for immunizing animals (e.g. mammals) against viral antigens, including herpes-simplex virus type 2. The protective immune response elicited by the methods and kits of the invention is characterized by robust humoral, cellular, and mucosal immunity. In particular, the invention provides a heterologous immunization method comprising a priming DNA vaccine encoding an antigen and a boosting protein vaccine, in which the protein form of the antigen is encapsulated in liposomes. Methods of preventing primary acute, latent and recurrent viral infections, such as that caused by HSV-2 virus, and methods of providing passive protective immunity against a viral pathogen such as HSV-2 virus to a mammal are also disclosed.
    Type: Application
    Filed: March 9, 2011
    Publication date: February 2, 2012
    Applicant: Biomedical Research Models, Inc.
    Inventors: Kejian YANG, Dennis L. Guberski
  • Publication number: 20080267963
    Abstract: The invention relates to methods and reagents for immunizing and treating individual with cancer to elicit specific cellular and humoral immune-responses against specific cancer cell surface antigens, including those cancer cell surface antigens expressed only in cancer cells and in non-cancer cells normally located in one or more immune-privileged sites or tissues of the individual. The invention provides methods of using specifically prepared immunogen in fresh or lyophilized liposome, proper routes of administration of the immunogen, proper doses of the immunogen, and specific combinations of heterologous immunization including DNA priming in one administration route followed by liposome-mediated protein antigen boost in a different route to tailor the immune responses in respects of enhancing cell mediated immune response, cytokine secretion, humoral immune response, especially skewing T helper responses to be Th1 or a balanced Th1 and Th2 type.
    Type: Application
    Filed: October 27, 2005
    Publication date: October 30, 2008
    Applicant: Biomedical Research Model, Inc.
    Inventors: Edward H. Kislauskis, Kejian Yang, Barbara J. Whalen
  • Publication number: 20060035853
    Abstract: The invention relates to methods and reagents for immunizing animals to elicit specific cellular and humoral immune-responses against specific antigens, such as viral antigens, including HBsAg antigen. The invention provides methods of using specifically prepared immunogen in fresh or lyophilized liposome, proper routes of administration of the immunogen, proper doses of the immunogen, and specific combinations of heterologous immunization including DNA priming in one administration route followed by liposome-mediated protein antigen boost in a different route to tailor the immune responses in respects of enhancing cell mediated immune response, cytokine secretion, humoral immune response, immune protection and selective skewing of T helper responses to be Th1, Th2, or a mixed or balanced Th response.
    Type: Application
    Filed: January 7, 2005
    Publication date: February 16, 2006
    Applicants: Biomedical Research Models, Inc., Oral Vaccine Technologies , Inc,
    Inventors: Kejian Yang, Barbara Whalen, Edward Kislauskis, Dennis Guberski