Patents by Inventor Kelledy Manson

Kelledy Manson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140213479
    Abstract: Methods and compositions for detecting immune responses and antigen-specific cells are described herein.
    Type: Application
    Filed: April 8, 2014
    Publication date: July 31, 2014
    Applicant: The United States of America, as represented by the Secretary, Department of Health and Human Serv
    Inventor: Kelledy Manson
  • Patent number: 8703484
    Abstract: The invention provides a method for detecting an antigen-specific hematopoietic cell in a biological sample, wherein the method comprises (a) providing a biological sample comprising a hematopoietic cell of a first species; (b) providing a target cell of a second species, wherein the second species is different from the first species, wherein the second species is a macaque species, and wherein the target cell comprises an antigen; (c) contacting the target cell with the sample; and (d) detecting an immune activation marker or activity in the sample, wherein an increase in expression of the immune activation marker or activity in the sample, relative to a control, is an indication that the sample comprises an antigen-specific hematopoietic cell; and wherein a cell identical to the target cell but lacking the antigen does not stimulate expression of the immune activation marker or activity in hematopoietic cells of the first species.
    Type: Grant
    Filed: May 5, 2006
    Date of Patent: April 22, 2014
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventor: Kelledy Manson
  • Publication number: 20090023174
    Abstract: Methods and compositions for detecting immune responses and antigen-specific cells are described herein.
    Type: Application
    Filed: May 5, 2006
    Publication date: January 22, 2009
    Applicant: Government of the United States of America, represented by the Secretary, Department of Health
    Inventor: Kelledy Manson