Abstract: A prosthetic valve may be used to repair a diseased or otherwise damaged heart valve such as the mitral valve. The prosthetic valve may include atraumatic anchor tabs which may be radiopaque or echogenic. A cinching mechanism may also be coupled to the prosthetic valve to control radial expansion of the prosthetic valve. The cinching mechanism may include a wire lasso or a belt. The prosthetic valve may include an expandable frame which has a reduced number of strut connection nodes to allow a lower profile collapsed configuration and tighter crimping. The commissure posts of the prosthetic valve may extend beyond an edge of the ventricular skirt portion of the device.

Abstract: A prosthesis delivery catheter has an inner distal capsule shaft and a distal capsule configured to house the prosthesis. An anchor catheter with an anchor hub is slidably disposed over the inner distal capsule shaft. An elbow catheter is slidably disposed over the anchor catheter, and a peg plate assembly is adjacent the anchor hub. The peg plate assembly has a plurality of protruding pegs and a plate which form a closed configuration with the pegs abutting the plate, and an open configuration where a gap is between the pegs and plate allowing release of a tether.

Abstract: A prosthetic delivery system may include a plurality of concentric shafts and an actuator mechanism for actuating one or more of the concentric shafts. A stop mechanism may be coupled to the actuator mechanism. The stop mechanism prevents advancement or retraction of at least some of the shafts beyond a predetermined position unless the stop mechanism is released. A second stop mechanism may be included in the system for controlling another of the shafts. A plurality of filaments may be coupled to a prosthesis carried by the delivery system and actuation of the filaments may be used to control deployment or retrieval of the prosthesis.

Abstract: A prosthetic delivery system may include a plurality of concentric shafts and an actuator mechanism for actuating one or more of the concentric shafts. A stop mechanism may be coupled to the actuator mechanism. The stop mechanism prevents advancement or retraction of at least some of the shafts beyond a predetermined position unless the stop mechanism is released. A second stop mechanism may be included in the system for controlling another of the shafts. A plurality of filaments may be coupled to a prosthesis carried by the delivery system and actuation of the filaments may be used to control deployment or retrieval of the prosthesis.

Abstract: An introducer sheath includes an elongate shaft having a proximal end, a distal end and a lumen extending therebetween. An actuatable hemostasis valve in a hub is adjacent the proximal end of the elongate shaft and may be used to prevent blood from escaping from the elongate shaft. The introducer sheath may also have a a self-expanding funnel adjacent the distal end of the elongate shaft.

Abstract: A prosthetic valve may be used to repair a diseased or otherwise damaged heart valve such as the mitral valve. The prosthetic valve may include atraumatic anchor tabs which may be radiopaque or echogenic. A cinching mechanism may also be coupled to the prosthetic valve to control radial expansion of the prosthetic valve. The cinching mechanism may include a wire lasso or a belt. The prosthetic valve may include an expandable frame which has a reduced number of strut connection nodes to allow a lower profile collapsed configuration and tighter crimping. The commissure posts of the prosthetic valve may extend beyond an edge of the ventricular skirt portion of the device.

Abstract: A prosthesis delivery catheter has an inner distal capsule shaft and a distal capsule configured to house the prosthesis. An anchor catheter with an anchor hub is slidably disposed over the inner distal capsule shaft. An elbow catheter is slidably disposed over the anchor catheter, and a peg plate assembly is adjacent the anchor hub. The peg plate assembly has a plurality of protruding pegs and a plate which form a closed configuration with the pegs abutting the plate, and an open configuration where a gap is between the pegs and plate allowing release of a tether.

Abstract: A prosthetic valve may be used to repair a diseased or otherwise damaged heart valve such as the mitral valve. The prosthetic valve may include atraumatic anchor tabs which may be radiopaque or echogenic. A cinching mechanism may also be coupled to the prosthetic valve to control radial expansion of the prosthetic valve. The cinching mechanism may include a wire lasso or a belt. The prosthetic valve may include an expandable frame which has a reduced number of strut connection nodes to allow a lower profile collapsed configuration and tighter crimping. The commissure posts of the prosthetic valve may extend beyond an edge of the ventricular skirt portion of the device.

Abstract: An introducer sheath includes an elongate shaft having a proximal end, a distal end and a lumen extending therebetween. An actuatable hemostasis valve in a hub is adjacent the proximal end of the elongate shaft and may be used to prevent blood from escaping from the elongate shaft. The introducer sheath may also have a a self-expanding funnel adjacent the distal end of the elongate shaft.

Abstract: A prosthetic valve may be used to repair a diseased or otherwise damaged heart valve such as the mitral valve. The prosthetic valve may include atraumatic anchor tabs which may be radiopaque or echogenic. A cinching mechanism may also be coupled to the prosthetic valve to control radial expansion of the prosthetic valve. The cinching mechanism may include a wire lasso or a belt. The prosthetic valve may include an expandable frame which has a reduced number of strut connection nodes to allow a lower profile collapsed configuration and tighter crimping. The commissure posts of the prosthetic valve may extend beyond an edge of the ventricular skirt portion of the device.

Abstract: A prosthetic delivery system may include a plurality of concentric shafts and an actuator mechanism for actuating one or more of the concentric shafts. A stop mechanism may be coupled to the actuator mechanism. The stop mechanism prevents advancement or retraction of at least some of the shafts beyond a predetermined position unless the stop mechanism is released. A second stop mechanism may be included in the system for controlling another of the shafts. A plurality of filaments may be coupled to a prosthesis carried by the delivery system and actuation of the filaments may be used to control deployment or retrieval of the prosthesis.